academic press jan 2012 (8 resultados)

Buch. Condición: Neu. Neuware - Flaviviruses are a diverse group of small RNA enveloped viruses, many of which are important human and animal pathogens. The best known include dengue virus, yellow fever virus, Japanese encephalitis virus, and West Nile virus. These viruses are endemic in many tropical and sub-tropical regions of the world. Dengue virus alone infects over 100 million people annually. In recent years, research on flaviviruses has progressed at a remarkable rate, leading to significant advances in our understanding of virus biology. This should ultimately lead to the development of better vaccine and antiviral strategies. This up-to-date and cutting-edge anthology contains contributions from the leading experts in the flavivirus field. Chapters are balanced by contributions from established investigators who have dedicated their careers to flavivirus research with those from newcomers who have recently made significant contributions to the flavivirus field. The book is divided into two sections: Molecular Virology and Virus Prevention. The first section on Molecular Virology covers: virion structure \* virus replication \* the NS1 glycoprotein \* the NS3 protein \* the NS5 protein \* innate immunity and flavivirus infection \* host responses to flavivirus infection \* flavivirus fitness and transmission. The Virus Prevention section includes: vaccines \* antibody therapy \* small molecule antiviral development \* flavivirus diagnostics \* vector-virus interactions \* vector control. The book represents an important update of flavivirus research and will serve as a reference to flavivirus researchers at the graduate level and beyond. It is a recommended text for all virology libraries.

Buch. Condición: Neu. Neuware - The vast majority of extremophiles are microbes, mainly archaea and bacteria, but also some eukaryotes. These microbes live under chemical and physical extremes that are usually lethal to cellular molecules, yet they manage to survive and even thrive. Extremophiles have important practical uses. They are a valuable source of industrially-important enzymes, and recent research has revealed novel mechanisms and biomolecular structures with a broad range of potential applications in biotechnology, biomining, and bioremediation. It is likely that biotechnology has only scratched the surface in its search for new organisms of practical use. This book highlights the current and topical areas of research in this rapidly growing field. Expert researchers from around the world provide the latest insights into the mechanisms these fascinating organisms use to survive. The topics covered include the ability of acidophiles to maintain a neutral intracellular pH, the way that psychrophiles 'loosen up' their proteins at low temperatures, and other equally ingenious adaptations and metabolic strategies that extremophiles use to survive and flourish under extreme conditions. The book also covers the established biotechnological uses of extremophiles and the most recent and novel applications, including the exploitation of these organisms for enzyme production, as well as their potential use in the generation of sustainable energy and in the oil industry. Aimed at research scientists, students, microbiologists, and biotechnologists, this book will be essential reading. It is a recommended reference text for anyone who is interested in the microbiology of these organisms, as well as for those interested in bioprospecting, biomining, biofuels, and extremozymes.

Buch. Condición: Neu. Neuware - Non-coding RNAs potentially play an active role in modulating gene transcription and epigenetic states. Several genes in differentiated cells may be under some form of RNA-based transcriptional and epigenetic regulatory control. This form of regulation may be controlled by selective pressures and influence the adaptability of the cell. The concept that RNA can control epigenetic states impacts our understanding of the basic fabric of the cell and may have therapeutic potential. Many studies have been carried out on the modulation of gene transcription by non-coding RNAs. This book, written by a group of distinguished scientists, represents an important overview and summary of the field to date. The 13 chapters are organized into three sections: a) Non-coding RNAs: Form, Function and Diversity; b) Non-coding RNAs: Gene Regulation and Epigenetics; and c) Non-coding RNAs: Disease and Therapeutics. This up-to-date volume is an essential book for those working in the area and represents a major information resource on current research in the fast-moving fields of epigenetics, the regulation of gene expression, and RNA research.

Buch. Condición: Neu. Neuware - The Encyclopedia of Applied Ethics, Second Edition, Four Volume Set addresses both the physiological and the psychological aspects of human behavior. Carefully crafted, well written, and thoroughly indexed, the encyclopedia helps users - whether they are students just beginning formal study of the broad field or specialists in a branch of psychology - understand the field and how and why humans behave as we do. The work is an all-encompassing reference providing a comprehensive and definitive review of the field. A broad and inclusive table of contents ensures detailed investigation of historical and theoretical material as well as in-depth analysis of current issues. Several disciplines may be involved in applied ethics: one branch of applied ethics, for example, bioethics, is commonly explicated in terms of ethical, legal, social, and philosophical issues. Editor-in-Chief Ruth Chadwick has put together a group of leading contributors ranging from philosophers to practitioners in the particular fields in question, to academics from disciplines such as law and economics. The 376 chapters are divided into 4 volumes, each chapter falling into a subject category including Applied Ethics; Bioethics; Computers and Information Management; Economics/Business; Environmental Ethics; Ethics and Politics; Legal; Medical Ethics; Philosophy/Theories; Social; and Social/Media. Concise entries (ten pages on average) provide foundational knowledge of the field Each article will features suggested readings pointing readers to additional sources for more information, a list of related websites, a 5-10 word glossary and a definition paragraph, and cross-references to related articles in the encyclopedia Newly expanded editorial board and a host of international contributors from the US, Australia, Belgium, Canada, France, Germany, Ireland, Israel, Japan, Sweden, and the United Kingdom The 376 chapters are divided into 4 volumes, each chapter falling into a subject category including Applied Ethics; Bioethics; Computers and Information Management; Economics/Business; Environmental Ethics; Ethics and Politics; Legal; Medical Ethics; Philosophy/Theories; Social; and Social/Media.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Winner of the 2012 Helen and Stan Vine Canadian Jewish Book Award in Holocaust Literature. A survivor of concentration camps and the Death March, Eli Pfefferkorn looks back on his Holocaust and post-Holocaust experiences to compare patterns of human behavior in extremis with those of ordinary life. What he finds is that the concentration camp Muselmann, who has lost his hunger for life and is thus shunned by his fellow inmates on the soup line, bears an eerie resemblance to an office employee who has fallen from grace and whose coworkers avoid spending time with him at the water cooler. Though the circumstances are unfathomably far apart, the human response to their situations is triggered by self-preservation rather than by calculated evil. By juxtaposing these two separate worlds, Pfefferkorn demonstrates that ultimately the human condition has not changed significantly since Cain slew Abel and the Athenians sentenced Socrates. 244 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is the first-ever roadmap to successful offshore wind installation. It provides a ready reference for wind project managers, teaching them how to deal with complications on-site, as well as for financers, who can utilize the text as an easy guide to asking the pivotal questions of petitioning wind project developers. These developers' planning stages will be improved by the book's expert advice on how to avoid wasting money by scoping out and mitigating potential problems up-front. Wind turbine manufacturers will benefit from insights into design optimization to support cheaper installation and hauling, thereby incurring lower project costs, and helping developers establish a quicker route to profitability. The book sheds light not just on HOW to solve a particular installation difficulty, but delves into WHY the problem may best be solved in that way.Enables all stakeholders to achieve cheaper, faster and safer offshore wind project realizationExplains the different approaches to executing on- and offshore projects, highlighting the economic impacts of the various financial and operational choicesProvides practical, proven advice on how tough challenges can be overcome, using real-life examples from the author's experiences to illustrate key issues 352 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The field of Genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge gained from genetics research. Advances in Genetics continually publishes important, timely reviews from leaders in the field that cover a broad range of topics of interest to geneticists and their colleagues in affiliated disciplines. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that bring together industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. Englisch.