rook graham (40 resultados)

Hardcover. Condición: Very Good. Estado de la sobrecubierta: Very Good. First Edition. Publisher's hardback in very good condition: firm, square and tight with no snags or splits, just a trifle rubbed. Complete with original dustjacket: in decent shape, just slightly rubbed and moderately edge-worn. Contents sound and clean; no pen-marks, just a Medical College bookplate at the endpaper. Thus a tidy book in presentable condition.

Paperback. Condición: New. Addenbrooke's Hospital has strongly influenced both the development of medical practice and the social history of Cambridge. This authoritative and absorbing account of the hospital traces in detail its history and development, from its benefaction in 1719 by John Addenbrooke, through its early years of expansion, reforms and modernisation and over the period of the two world wars. With the use of rare and previously unseen archive material, including the original minutes, the authors have produced a careful, authoritative and fascinating account of the history and development of one of Britain's most famous hospitals. Embellished with evocative and often rare documentary illustrations, this book will be of the greatest interest and value to all those associated with Addenbrooke's: clinicians, nursing and administrative staff, students and patients, as well as to anyone with an interest in the social and medical history of Cambridge.

Hardback. Condición: nrFine. Estado de la sobrecubierta: VG+ DW. 1st Edition. DW spine is sunned (title still legible).

Paperback. Condición: New. Addenbrooke's Hospital has strongly influenced both the development of medical practice and the social history of Cambridge. This authoritative and absorbing account of the hospital traces in detail its history and development, from its benefaction in 1719 by John Addenbrooke, through its early years of expansion, reforms and modernisation and over the period of the two world wars. With the use of rare and previously unseen archive material, including the original minutes, the authors have produced a careful, authoritative and fascinating account of the history and development of one of Britain's most famous hospitals. Embellished with evocative and often rare documentary illustrations, this book will be of the greatest interest and value to all those associated with Addenbrooke's: clinicians, nursing and administrative staff, students and patients, as well as to anyone with an interest in the social and medical history of Cambridge.

Pp. Condición: Sehr gut. XII, 305 S. : Ill., graph. Darst. ; 24 cm Die Kernaussage: Moderne Lebensbedingungen reduzieren die Exposition gegenüber Mikroorganismen mit Folgen für die Regulation des Immunsystems und die Zunahme chronisch-entzündlicher Erkrankungen. Die Pämisse: Rook beschreibt, dass der Übergang vom Jäger-Sammler-Leben zu modernen Industriegesellschaften die Mikrobenexposition drastisch reduziert hat. Dies führt zu Fehlregulationen des Immunsystems und damit zu einem Anstieg von: allergischen Erkrankungen, Autoimmunerkrankungen, entzündlichen Darmerkrankungen, Atherosklerose, Depressionen mit entzündlicher Komponente, möglicherweise, Alzheimer und Parkinson. Die Hygienehypothese wird in einen evolutionären Kontext gestellt: Der menschliche Organismus ist an eine Umwelt angepasst, in der dauerhafte mikrobielle Stimulation normal war. Das moderne Mikroben-Defizit erzeugt evolutionär unpassende Immunreaktionen. Der Autor verbindet bei seinem Denkweg mikrobiologische Evolutionsgeschichte, Immunologie, Epidemiologie, klinische Beispiele aus vielen Organsystemen, therapeutische Perspektiven. Sprache: Englisch Gewicht in Gramm: 855.

Condición: New.

Hardcover. Condición: new. Hardcover. This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the hygiene hypothesis by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Hardcover. Condición: Brand New. 424 pages. 9.25x6.10x0.87 inches. In Stock.

Condición: As New. Unread book in perfect condition.

Taschenbuch. Condición: Neu. Evolution, Biodiversity and a Reassessment of the Hygiene Hypothesis | Graham A. W. Rook (u. a.) | Taschenbuch | Progress in Inflammation Research | x | Englisch | 2023 | Springer | EAN 9783030910532 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Condición: New. In.

Buch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the 'hygiene hypothesis' by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation.

Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the 'hygiene hypothesis' by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation.

Condición: New. 1st ed. 2022 edition NO-PA16APR2015-KAP.

Condición: New. 1st ed. 2022 edition NO-PA16APR2015-KAP.

Condición: New.

Hardcover. Condición: Brand New. 424 pages. 9.25x6.10x0.87 inches. In Stock.

paperback. Condición: New. NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Hardcover. Condición: new. Hardcover. This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the hygiene hypothesis by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.

Condición: As New. Unread book in perfect condition.

Condición: New. This book takes an interdisciplinary approach in discussing the evidence for and against the so-called 'hygiene hypothesis'. It does so in the context of Darwinian medicine, which deploys our knowledge of evolution in an effort to cast light on human diseases. Series: Progress in Inflammation Research. Num Pages: 308 pages, 10 black & white tables, biography. BIC Classification: MJCJ; MJCM; MMFM. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 23. Weight in Grams: 885. . 2009. Hardback. . . . .

Buch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Man has moved rapidly from the hunter-gatherer environment to the living conditions of industrialised countries. The hygiene hypothesis suggests that the resulting reduced exposure to micro-organisms has led to disordered regulation of the immune system, and hence to increases in certain chronic inflammatory disorders, like allergic disorders, autoimmunity, inflammatory bowel disease, atherosclerosis, depression, some cancers and perhaps Alzheimer and Parkinson. This book discusses the evidence for and against in the context of Darwinian medicine, which uses knowledge of evolution to cast light on human diseases. The approach is interdisciplinary, looking at man's microbiological history, at the biology of the effects of microorganisms on the immune system, and at the implications for chronic inflammatory disorders in multiple organ systems. Finally, the authors describe progress in the exploitation of microorganisms or their components as novel prophylactics and treatments.

Hardcover. Condición: Brand New. 1st edition. 317 pages. 9.21x6.61x0.94 inches. In Stock.

Condición: New. This book takes an interdisciplinary approach in discussing the evidence for and against the so-called 'hygiene hypothesis'. It does so in the context of Darwinian medicine, which deploys our knowledge of evolution in an effort to cast light on human diseases. Series: Progress in Inflammation Research. Num Pages: 308 pages, 10 black & white tables, biography. BIC Classification: MJCJ; MJCM; MMFM. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 23. Weight in Grams: 885. . 2009. Hardback. . . . . Books ship from the US and Ireland.

Paperback. Condición: Brand New. 1st edition. 535 pages. 8.98x5.98x1.42 inches. In Stock. This item is printed on demand.

Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. This authoritative and absorbing account of Addenbrooke s Hospital tracing its history and development, from its early years of expansion, reforms and modernisation to the two world wars. This book will be of interest to clinicians, nursing and administrati.

Condición: new. Questo è un articolo print on demand.

Kartoniert / Broschiert. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Explains why we evolved a need for exposure to the microbiota of our mothers and of the natural environmentSummarises the physiological roles of these microbial exposures, and what goes wrong when they are missingResolves the confusion in t.

Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Explains why we evolved a need for exposure to the microbiota of our mothers and of the natural environmentSummarises the physiological roles of these microbial exposures, and what goes wrong when they are missingResolves the confusion in t.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the 'hygiene hypothesis' by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation. 424 pp. Englisch.