murali gopalakrishnan (1 resultados)

Hardcover. Condición: Near Fine. 1st Edition. Hardcover, xii + 479 pages, NOT ex-library. Weight over 1060g. Minor handling wear, book is clean, with unmarked text, free of inscriptions and stamps, firmly bound. Issued without a dust jacket. -- The book provides an in-depth exploration of voltage-gated ion channels, which play crucial roles in various physiological processes and are significant targets for drug discovery. It covers the fundamental principles of ion channel biology, the methodologies employed in studying these channels, and the latest advancements in targeting them for therapeutic purposes. -- Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development. For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.