Jijun hao (1 resultados)

Hardcover. Condición: Very Good. 1st Edition. Hardcover, xii + 219 pages, NOT ex-library. A gentle diagonal corner crease on p.43. Else clean and bright throughout with unmarked text, free of inscriptions and stamps, firmly bound. Boards show moderate shelfwear, a few short scratches. Published without a dust jacket. -- Contents: 1 Wnt Signaling in Regulation of Stem Cells [Overview; Wnt Signaling in Embryonic Stem Cells & in Cardiovascular Progenitor Cells and Cardiomyocyte Differentiation & in Mesenchymal Stem Cells & in Hematopoiesis and Hematopoietic Stem Cells & in Neural Stem Cells & in Endothelial-Mesenchymal Transition] 2 Directed Cardiomyogenesis of Pluripotent Stem Cells [Brief Review of Heart Development; Introduction to Pluripotent Stem Cells; Cardiomyocyte Differentiation] 3 Chemical Genetics in Cardiomyocyte Generation [iPSC Generation; Chemical Genetics Approach in iPSC Generation; Heart Regeneration; Chemical Genetics Approach in Heart Regeneration; Cardiac Cell Transdifferentiation] 4 Challenges and New Directions for Cardiac Reprogramming [Strategies for Heart Repair; Direct Reprogramming Approaches; Current Challenges] 5 Comparative Analysis of Adult Stem Cell Niches [Adult Stem Cells; Adult Stem Cell Niches; Hair Follicle Stem Cell (HFSC) Niche; Intestinal Stem Cell (ISC) Niche; Hematopoietic Stem Cell (HSC) Niche; Neural Stem Cell (NSC) Niche; Comparison between Tissue-Specific Adult Stem Cell Niches; Future Challenges] 6 Chemicals and Stem Cells in the Promotion of Regeneration [Biologics in Regenerative Medicine; Chemicals and Biomaterials for Healing; Stem-Cell Therapy] 7 Chemically Induced Pluripotent Stem Cells (CiPSCs): A Potential Chemical Biological Breakthrough in Reprogramming? [Searching for the Perfect Platform; Defining the Advantages of Small Molecules in Reprogramming; Understanding the Disadvantages of Using Small Molecules; Breakthrough: The CiPSC Paradigm] 8 An Introduction to Cellular Reprogramming: The Plasticity of Cell Fates and Identities [Defining Cell Potency; Types of Pluripotent Cell; Defining Pluripotency; Molecular Basis of Pluripotency; Cellular Reprogramming: Altering the Epigenetic State; Cellular Reprogramming: Primary Regulatory Pathways; Reprogramming Methods; Applications and Future Trends] 9 Chemicals Facilitating Reprogramming [Chemicals Modulating Epigenetic Barriers; Chemicals Targeting Signaling Pathways; Chemicals Promoting Lineage Reprogramming] 10 Chemicals Facilitating Reprogramming: Targeting the SAM Binding Site to Identify Novel Methyltransferase Inhibitors [DNA Methyltransferases, Inhibition, and Reprogramming; DNMT Inhibitors; Histone Methyltransferases, Inhibition, and Reprogramming; Inhibitors of Lysine Methyltransferases; Identification of DNMT1 Inhibitor Candidates Using Virtual Screening; Targeting the SAM Binding Site to Identify Novel HMT Inhibitors] 11 Biomaterials for Directed Differentiation [Natural Biomaterials; Synthetic Biomaterials (Polyesters; Polyethylene Glycol)] 12 Practicalities to Translation from the Clinic to the Market [Commercialization Comparison with Small Molecules, Medical Devices, and Biologics; Historical Review and Case Studies (Dermagraft; Provenge); Commercialization Challenges and How to Overcome Them; Translation from the Bench to the Clinic: Key Considerations]; Index.…