Gosling e m (15 resultados)

Soft cover. Condición: Near Fine. 1st Edition. First Edition, First Printing of this Collection of 11 Short Stories. Featured are The 1944 Bullet by Jeffry Scott, A Fondness for Steam by Edward D Hoch, Passion Flower by Jo Bannister, The Case of the Runaway Husband by Tom Tolnay, The Saturday Shopper by Paula Gosling, The Jury Box by Jon L Breen, A Delicate Balance by Judith Lea Koretsky, Skeleton in the Cupboard by Tony Wilmot, Death on the Reach by Claire M Caterer, Gains and Losses by Michael Z Lewin and Iceman by Peter Turnbull. In Near Fine Condition.…

Soft cover. Condición: Good. paperback, large 8vo, x,65pp, owner's name on endpaper, edges slightly browned, contents clean and tight, Good condition. ISBN: 0333258258.

Encuadernación de tapa blanda. Condición: Aceptable. R802906. Ed. Paraninfo - 80pp Códigos ponderacos, procedimientos prácticos, etc. CA. G109125.

tapa blanda. Condición: 2ª Mano - Aceptable. 2ª Mano. Thomson Paraninfo,S.A. 1981. Firma de anterior propietario , Marcas de cello por forro, Portada sobada. Moteado en cantos y guardas. Libro.

Broché. Condición: Etat satisfaisant. in-8 Description :169 pp. Collection "Science de l'homme". Poinçons "SP" sur le 4ème plat et les dernières pages. Ouvrage jauni. Couverture défraichie. Langue : Français Nb de volumes : 1.

paperback. Condición: New. Language:Chinese.Paperback. Publisher: China Electric Power Press. This book describes in detail the syntax. type. value. and.

Condición: New.

Condición: As New. Unread book in perfect condition.

Condición: New. pp. x + 443, Maps, Index.

1st Edition. FIRST EDITION OF A NUMBER OF IMPORTANT PAPERS. ALSO INCLUDED: Armenteros, R.; Barker, K. H. "Decay of Neutral V-Particles" WITH Mackay, D. M., Calculating Machines and Human Thought WITH Bragg, W. L. Elimination of the Unwanted Image in Diffraction Microscopy WITH Martyn, D. G. The Theory of Magnetic Storms and Auroras. CONDITION & DETAILS: London: Macmillian & Sons. Complete volume. 4to (10.25.x 7.5 inches; 256 x 186mm). 1076 pp. & lv name and title index. Ex-libris bearing only discrete stamps on the flyleaf, pastedown and title page; no spine markings whatsoever. Bound in blue cloth, gilt-lettered at the spine. Solidly and tightly bound; light rubbing at the edges. Very clean inside and out. Very good condition.…

First Edition. Offprint, 8vo (210 x 140mm), pp. 14, with two diagrams (including the double helix) and two illustrations from photographs. The three-paper offprint issue, of the primary record of the co-discovery of the molecular structure of DNA, the most transformative moment in twentieth-century biology. Stapled in self-wrappers as issued. Signed by Maurice Wilkins on the first page. Very lightly toned and a coulpe soft creases, near fine. Grolier Club, One Hundred Books Famous in Medicine, 99; Dibner, Heralds of Science, 200. Garrison-Morton 256.3; Judson, Eighth Day of Creation, pp. 145-56. Ex-Dr. Myron Printzmetal. The discovery of DNA's double helix structure emerged from an intense period of competitive collaboration between research teams at Cambridge and King's College London. Watson and Crick's theoretical breakthrough synthesized crucial experimental evidence from multiple sources: Erwin Chargaff's base composition rules demonstrating the 1:1 ratio of adenine to thymine and guanine to cytosine, X-ray crystallographic data revealing DNA's helical structure, and most critically, the precise measurements of backbone positioning and molecular dimensions. Their elegant model proposed complementary base pairing (A-T and C-G) held together by hydrogen bonds, immediately suggesting a mechanism for genetic replication where each strand could serve as a template for its complement. The accompanying papers by Wilkins, Stokes, and Wilson, and by Franklin and Gosling, provided essential experimental validation through X-ray diffraction analysis, creating a unified presentation of both theoretical insight and empirical evidence that established the foundation of molecular biology. The contentious history surrounding this discovery has generated enduring scholarly debate, particularly regarding the systematic marginalization of Rosalind Franklin's contributions. Franklin's meticulous X-ray crystallographic work, conducted with her graduate student Raymond Gosling, had independently determined many key structural features including the antiparallel orientation of DNA strands, the external positioning of phosphate groups, and precise helical parameters. Her famous "Photograph 51" provided definitive evidence of DNA's helical structure, while her systematic analysis of A-form and B-form DNA revealed critical dimensions that enabled Watson and Crick's model construction. As Brenda Maddox documents in "Rosalind Franklin: The Dark Lady of DNA," Franklin's data was shown to Watson and Crick without her knowledge through Maurice Wilkins, creating an ethical controversy that persists in discussions of scientific collaboration and gender bias. Franklin's death from ovarian cancer in 1958, four years before the Nobel Prize was awarded to Watson, Crick, and Wilkins, has intensified debates about recognition and the complex dynamics of mid-twentieth century scientific discovery, with many scholars arguing that her rigorous experimental approach was as fundamental to the breakthrough as the theoretical modeling that received greater acclaim. This publication represents the founding document of modern molecular biology, establishing the conceptual framework for understanding heredity, genetic replication, and the molecular basis of life itself. The discovery immediately suggested mechanisms for protein synthesis and genetic information transfer, creating the theoretical foundation for subsequent developments in genetic engineering, biotechnology, and genomic medicine. As Francis Crick later observed, the structure's elegant simplicitywith its complementary base pairing and antiparallel strandsprovided not merely a static model but a dynamic mechanism explaining how genetic information could be accurately copied and transmitted across generations. The offprint's scientific significance extends far beyond its immediate discovery, representing the moment when biology transformed from a primarily descriptive science into a molecular discipline capable of manipulating the fundamental mechanisms of life, establishing the intellectual foundation for the biotechnology revolution that continues to reshape medicine, agriculture, and our understanding of evolutionary processes seventy years after its publication.…

Soft cover. Condición: Very Good. 1st Edition. 7 pp. Original wrappers. Very Good. First Edition. SIGNED BY MAURICE WILKINS AND BY RAYMOND GOSLING, on the front wrapper. At a meeting of the Faraday Society in May 1950, Rudolf Signer "gave out samples of his best [DNA], and Wilkins took some home to King's. A few days later, he was preparing part of this DNA in highly viscous solution for the ultraviolet studies he was doing. Unexpectedly, he noticed that every time he touched the stuff with the tip of a glass rod and then drew the rod away, 'I had spun a very thin fibre of DNA, almost invisible, like a filament of spider web.' The fibres seemed so perfect and uniform that the molecules in them must have been neatly aligned alongside one another. Examined under a microscope, in polarized light, the fibres behaved as though they were made up of well-ordered crystals. So Wilkins took the fibres to a graduate student in the unit, Raymond Gosling, who was doing the crystallography with rams' sperm and had borrowed the use of an antiquated x-ray apparatus in a lead-lined basement of the chemistry department. Several dozen of Wilkins's fibres had to be bundled together, in a tiny tungsten-wire frame where they could be tightened like a violin bow, to constitute a large enough specimen for the soft focus of the x-ray tube. Wilkins and Gosling remembered that Bernal, fifteen years before, had got the first good x-ray patterns from protein crystals by keeping them wet. Accordingly, they maintained the DNA fibres at high humidity. They got striking patterns, with many spots, sharp and detailed, far better than ever before seen from DNA, and for the first time unmistakably from a substance in crystalline form. . . . That series of diffraction pictures taken in May or June of 1950 provided the one Wilkins showed at the meeting in Naples, a year later, that galvanized Watson's enthusiasm for DNA and x-ray crystallography" (Judson, Eighth Day of Creation, expanded ed., pp. 78-79). Olby, The Path to the Double Helix, pp. 332-335 (including an illustration taken from Wilkins and Gosling's paper). Maurice Wilkins shared the Nobel Prize in 1962 in Physiology or Medicine with Francis H. C. Crick and James D. Watson "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material.". Signed by Author(s).…

Condición: New. pp. x + 443 Illus., Maps This item is printed on demand.