benet leslie (15 resultados)

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Hardcover. Condición: Good. No Jacket. 0917330110. Hardcover, from closed pharmaceutical company library, light edge and corner wear. 252 pages, index, illustrated with charts and tables. Sections include: Body Perfusuion; Hepatic and Metabolic Function; Protein Binding; Renal Function. Contents clean, tight and bright. Book.

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Taschenbuch. Condición: Neu. Pharmacokinetics | A Modern View | Leslie Z. Benet (u. a.) | Taschenbuch | 548 S. | Englisch | 2011 | Springer | EAN 9781461297253 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

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Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - InhaltsangabeSidney Riegelman, the Man, His Work and His Impact.- 1. Sidney Riegelman - The Wisconsin Years.- 2. Sidney Riegelman - Friend and Colleague.- 3. Signey Riegelman - The Educator.- 4. Sidney Riegelman - The Scientist.- 5. Sidney Riegelman - His Contributions to Public Policy in Pharmacy and the Pharmaceutical Sciences.- 6. Sidney Riegelman - Contributions at the Clinical Interface.- Biopharmaceutics - Drug Delivery.- 7. Personal Experiences in the Early Days of Biopharmacy and Pharmacokinetics.- 8. Modern Pharmaceutical Dosage Forms.- 9. Specificity of Esterases and Effect of Structure of Prodrug Esters of Acylated Acetaminophen on Hydrolytic Reactivity.- 10. Transdermal Absorption: A Unique Opportunity for Drug Delivery.- 11. Pharmacokinetics and Pharmaceutical Technology.- 12. Bioavailability and Pharmacokinetics in Drug Development.- Pharmacokinetics - Concepts, Theory and Application.- 13. Clearance - Models, Validation and Implications.- 14. Estimation of an Effective Half-Life.- 15. Pharmacokinetic Aspects of Nonlinear Drug-Protein Binding.- 16. Unusual Pharmacokinetics.- Pharmacokinetics and Drug Metabolism.- 17. Assessment and Prediction of In Vivo Oxidative Drug Metabolizing Activity.- 18. Pharmacokinetic and Pharmacological Aspects of Polymorphic Drug Oxidation in Man.- 19. Problems in Correlating In Vitro and In Vivo Studies of Drug Metabolism.- 20. Integral Procedures in Pharmacokinetics and Their Application to the Parameter Determination of Appearing Metabolites.- 21. Pharmacokinetics at the Interface Between Pharmacology and Physiology.- Pharmacokinetics - Drug Dosing and Drug Effects.- 22. Methods for Drug Dosage Individualization: Past, Present and Future.- 23. Treatment of Depression - Pharmacokinetic and Pharmacogenetic Considerations.- 24. Kinetics of Drug Action.- Pharmacokinetics and Biopharmaceutics of Chemotherapeutic and Immunosuppressive Agents.- 25. Cancer Drug Delivery Systems: Macromolecular Prodrugs of Mitomycin C.- 26. Organ Variation in Tissue to Plasma Partition Coefficients of Adriamycin, Daunomycin and Actinomycin-D: Correlation to Tissue DNA Concentrations.- 27. Clinical Pharmacokinetics in the Therapeutic Management of Cancer Patients with Methotrexate and Adriamycin.- 28. The Immunopharmacokinetics of Prednisone/ Prednisolone.- Communications.- 1. The Interpretation of In Vivo Mean Dissolution Time Data.- 2. Application of Statistical Moment Analysis to the Evaluation of Controlled Release Formulations.- 3. Concept of Time-Averaged Total Clearance and Mean Residence Time in Michaelis-Menten Elimination Systems.- 4. A General Method of Optimizing Individual Drug Dosage.- 5. Estimation of Population Pharmacokinetic Parameters with the Computer System NONMEM: Patients Treated with Lidocaine and Mexiletine.- 6. Considerations of Linear Regression with Errors in Both Variables as Applied to Clinical Pharmacokinetics.- 7. Intestinal Drug Metabolism - Presystemic and Systemic Mechanisms and Implications.- 8. Pharmacokinetics of Aspirin: Total and Presystemic Clearance by Rats and Hydrolysis in Blood of Rats and Humans.- 9. Do Plasma Concentrations of Acetaminophen and Its Conjugated Metabolites Reflect Concentrations in Various Tissues .- 10. Interspecies Variations in Pharmacokinetics: A Perspective.- 11. Nonrenal Elimination, Extensive Renal Tubular Reabsorption and Secretion of Creatinine in Humans and Animals.- 12. Phenobarbital Pharmacokinetics with Particular Emphasis on the Treatment of Overdosed Patients.- 13. Renal Elimination in Alcoholic Cirrhosis.- 14. Altered Disposition of Naproxen by Cirrhotic and by Elderly Individuals.- 15. Drug-Drug Interactions: Protean Manifestations.- 16. Kinetics and Antiarrhythmic Effect of Dihydroquinidine.- 17. Quinidine-N-Oxide: Structure and Pharmacokinetics of a New Quinidine Metabolite.- 18. Phenobarbital Inductions of Quinidine Plasma Protein Binding in Dogs and Its Effect on Quinidine D.

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -InhaltsangabeSidney Riegelman, the Man, His Work and His Impact.- 1. Sidney Riegelman - The Wisconsin Years.- 2. Sidney Riegelman - Friend and Colleague.- 3. Signey Riegelman - The Educator.- 4. Sidney Riegelman - The Scientist.- 5. Sidney Riegelman - His Contributions to Public Policy in Pharmacy and the Pharmaceutical Sciences.- 6. Sidney Riegelman - Contributions at the Clinical Interface.- Biopharmaceutics - Drug Delivery.- 7. Personal Experiences in the Early Days of Biopharmacy and Pharmacokinetics.- 8. Modern Pharmaceutical Dosage Forms.- 9. Specificity of Esterases and Effect of Structure of Prodrug Esters of Acylated Acetaminophen on Hydrolytic Reactivity.- 10. Transdermal Absorption: A Unique Opportunity for Drug Delivery.- 11. Pharmacokinetics and Pharmaceutical Technology.- 12. Bioavailability and Pharmacokinetics in Drug Development.- Pharmacokinetics - Concepts, Theory and Application.- 13. Clearance - Models, Validation and Implications.- 14. Estimation of an Effective Half-Life.- 15. Pharmacokinetic Aspects of Nonlinear Drug-Protein Binding.- 16. Unusual Pharmacokinetics.- Pharmacokinetics and Drug Metabolism.- 17. Assessment and Prediction of In Vivo Oxidative Drug Metabolizing Activity.- 18. Pharmacokinetic and Pharmacological Aspects of Polymorphic Drug Oxidation in Man.- 19. Problems in Correlating In Vitro and In Vivo Studies of Drug Metabolism.- 20. Integral Procedures in Pharmacokinetics and Their Application to the Parameter Determination of Appearing Metabolites.- 21. Pharmacokinetics at the Interface Between Pharmacology and Physiology.- Pharmacokinetics - Drug Dosing and Drug Effects.- 22. Methods for Drug Dosage Individualization: Past, Present and Future.- 23. Treatment of Depression - Pharmacokinetic and Pharmacogenetic Considerations.- 24. Kinetics of Drug Action.- Pharmacokinetics and Biopharmaceutics of Chemotherapeutic and Immunosuppressive Agents.- 25. Cancer Drug Delivery Systems: Macromolecular Prodrugs of Mitomycin C.- 26. Organ Variation in Tissue to Plasma Partition Coefficients of Adriamycin, Daunomycin and Actinomycin-D: Correlation to Tissue DNA Concentrations.- 27. Clinical Pharmacokinetics in the Therapeutic Management of Cancer Patients with Methotrexate and Adriamycin.- 28. The Immunopharmacokinetics of Prednisone/ Prednisolone.- Communications.- 1. The Interpretation of In Vivo Mean Dissolution Time Data.- 2. Application of Statistical Moment Analysis to the Evaluation of Controlled Release Formulations.- 3. Concept of Time-Averaged Total Clearance and Mean Residence Time in Michaelis-Menten Elimination Systems.- 4. A General Method of Optimizing Individual Drug Dosage.- 5. Estimation of Population Pharmacokinetic Parameters with the Computer System NONMEM: Patients Treated with Lidocaine and Mexiletine.- 6. Considerations of Linear Regression with Errors in Both Variables as Applied to Clinical Pharmacokinetics.- 7. Intestinal Drug Metabolism - Presystemic and Systemic Mechanisms and Implications.- 8. Pharmacokinetics of Aspirin: Total and Presystemic Clearance by Rats and Hydrolysis in Blood of Rats and Humans.- 9. Do Plasma Concentrations of Acetaminophen and Its Conjugated Metabolites Reflect Concentrations in Various Tissues .- 10. Interspecies Variations in Pharmacokinetics: A Perspective.- 11. Nonrenal Elimination, Extensive Renal Tubular Reabsorption and Secretion of Creatinine in Humans and Animals.- 12. Phenobarbital Pharmacokinetics with Particular Emphasis on the Treatment of Overdosed Patients.- 13. Renal Elimination in Alcoholic Cirrhosis.- 14. Altered Disposition of Naproxen by Cirrhotic and by Elderly Individuals.- 15. Drug-Drug Interactions: Protean Manifestations.- 16. Kinetics and Antiarrhythmic Effect of Dihydroquinidine.- 17. Quinidine-N-Oxide: Structure and Pharmacokinetics of a New Quinidine Metabolite.- 18. Phenobarbital Inductions of Quinidine Plasma Protein Binding in Dogs and Its Effec.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Sidney Riegelman, the Man, His Work and His Impact.- 1. Sidney Riegelman - The Wisconsin Years.- 2. Sidney Riegelman - Friend and Colleague.- 3. Signey Riegelman - The Educator.- 4. Sidney Riegelman - The Scientist.- 5. Sidney Riegelman - His Contributions to Public Policy in Pharmacy and the Pharmaceutical Sciences.- 6. Sidney Riegelman - Contributions at the Clinical Interface.- Biopharmaceutics - Drug Delivery.- 7. Personal Experiences in the Early Days of Biopharmacy and Pharmacokinetics.- 8. Modern Pharmaceutical Dosage Forms.- 9. Specificity of Esterases and Effect of Structure of Prodrug Esters of Acylated Acetaminophen on Hydrolytic Reactivity.- 10. Transdermal Absorption: A Unique Opportunity for Drug Delivery.- 11. Pharmacokinetics and Pharmaceutical Technology.- 12. Bioavailability and Pharmacokinetics in Drug Development.- Pharmacokinetics - Concepts, Theory and Application.- 13. Clearance - Models, Validation and Implications.- 14. Estimation of an Effective Half-Life.- 15. Pharmacokinetic Aspects of Nonlinear Drug-Protein Binding.- 16. Unusual Pharmacokinetics.- Pharmacokinetics and Drug Metabolism.- 17. Assessment and Prediction of In Vivo Oxidative Drug Metabolizing Activity.- 18. Pharmacokinetic and Pharmacological Aspects of Polymorphic Drug Oxidation in Man.- 19. Problems in Correlating In Vitro and In Vivo Studies of Drug Metabolism.- 20. Integral Procedures in Pharmacokinetics and Their Application to the Parameter Determination of Appearing Metabolites.- 21. Pharmacokinetics at the Interface Between Pharmacology and Physiology.- Pharmacokinetics - Drug Dosing and Drug Effects.- 22. Methods for Drug Dosage Individualization: Past, Present and Future.- 23. Treatment of Depression - Pharmacokinetic and PharmacogeneticConsiderations.- 24. Kinetics of Drug Action.- Pharmacokinetics and Biopharmaceutics of Chemotherapeutic and Immunosuppressive Agents.- 25. Cancer Drug Delivery Systems: Macromolecular Prodrugs of Mitomycin C.- 26. Organ Variation in Tissue to Plasma Partition Coefficients of Adriamycin, Daunomycin and Actinomycin-D: Correlation to Tissue DNA Concentrations.- 27. Clinical Pharmacokinetics in the Therapeutic Management of Cancer Patients with Methotrexate and Adriamycin.- 28. The Immunopharmacokinetics of Prednisone/ Prednisolone.- Communications.- 1. The Interpretation of In Vivo Mean Dissolution Time Data.- 2. Application of Statistical Moment Analysis to the Evaluation of Controlled Release Formulations.- 3. Concept of Time-Averaged Total Clearance and Mean Residence Time in Michaelis-Menten Elimination Systems.- 4. A General Method of Optimizing Individual Drug Dosage.- 5. Estimation of Population Pharmacokinetic Parameters with the Computer System NONMEM: Patients Treated with Lidocaine and Mexiletine.- 6. Considerations of Linear Regression with Errors in Both Variables as Applied to Clinical Pharmacokinetics.- 7. Intestinal Drug Metabolism - Presystemic and Systemic Mechanisms and Implications.- 8. Pharmacokinetics of Aspirin: Total and Presystemic Clearance by Rats and Hydrolysis in Blood of Rats and Humans.- 9. Do Plasma Concentrations of Acetaminophen and Its Conjugated Metabolites Reflect Concentrations in Various Tissues .- 10. Interspecies Variations in Pharmacokinetics: A Perspective.- 11. Nonrenal Elimination, Extensive Renal Tubular Reabsorption and Secretion of Creatinine in Humans and Animals.- 12. Phenobarbital Pharmacokinetics with Particular Emphasis on the Treatment of Overdosed Patients.- 13. Renal Elimination in Alcoholic Cirrhosis.- 14.Altered Disposition of Naproxen by Cirrhotic and by Elderly Individuals.- 15. Drug-Drug Interactions: Protean Manifestations.- 16. Kinetics and Antiarrhythmic Effect of Dihydroquinidine.- 17. Quinidine-N-Oxide: Structure and Pharmacokinetics of a New Quinidine Metabolite.- 18. Phenobarbital Inductions of Quinidine Plasma Protein Binding in Dogs and Its Effect on Quinidine Disposition.- 19. Covalent Binding of QuinidiSpringer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 548 pp. Englisch.