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The Renin-Angiotensin System: Current Research Progress in The Pancreas: The RAS in the Pancreas: 690 (Advances in Experimental Medicine and Biology) - Tapa blanda
Sinopsis
Highlighting the role local renin-angiotensin systems (RAS) play in pancreatic disease, this review presents the latest research advances in the field. These findings suggest both preventative measures and treatment for pancreatic disease.
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The human pancreas has vital roles in the regulation of glucose homeostasis and digestion and its dysfunction leads to pancreatic disease as diabetes and pancreatitis. Recent researches have highlighted the novel roles of a local renin-angiotensin system (RAS) in the pancreas and its clinical relevances; its inapprporiate activation leads to pancreatic endocrine and exocrine disease, notably type 2 diabetes. As such, manipulation of the overactive RAS may improve pancreatic islet cell function, cell mass and insulin sensitivity, as well as enhancing the growth and differentiation of pancreatic stem cells. Blockade of the RAS may be protective against pancreatitis and pancreatic cancer. The research outcome of current progress on the RAS in the pancreas should provide an alternative approach to preventing and treating, as well as curing pancreatic disease. This book discusses the progress of research on the renin-angiotensin system in the pancreas from the science to the bedside, providing a timely review of this expanding area. It consists of ten interrelated chapters covering subjects as: Structure, physiology and disease of the pancreas Biochemistry and physiology of the pancreatic renin-angiotensin system RAS in diabetes, stem cells and pancreatitisThis book is of special value to basic and clinical scientists, clinicians, graduate students, as well as novices in this field.
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Renin-angiotensin System : Current Research Progress in the Pancreas - the Ras in the Pancreas
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The Renin-Angiotensin System: Current Research Progress in The Pancreas (Paperback)
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Paperback. Condición: new. Paperback. The human pancreas consists of two organs in one: the exocrine gland made up of pancreatic acinar cells and duct cells that produce digestive enzymes and sodium bicarbonate, respectively; the endocrine gland made up of four islet cells, namely alpha-, beta-, delta- and PP-cells that produce glucagon, insulin, somatostatin and pancreatic polypeptide, respectively. While the physiological role of exocrine p- creas is to secrete digestive enzyme responsible for our normal digestion, absorption and assimilation of nutrients, the endocrine pancreas is to secrete islet peptide h- mones maintaining our glucose homeostasis. The pancreatic functions are nely regulated by neurocrine, endocrine, paracrine and/or intracrine mechanisms. Thus, dysregulation of these pathways should have signi cant impacts on our health and disease. Nevertheless, the underlying mechanisms by which pancreatic functions are regulated remain poorly understood. Recent basic science and clinical studies con rm myriad physiological and pathophysiological roles of the tissue renin-angiotensin systems (RAS).Of parti- lar interest is the recent identi cation of a local and functional RAS in the pancreas, which in uences both its exocrine and endocrine function. Its role in the pat- genesis of pancreatic diseases including diabetes and pancreatitis is increasingly recognized, as is the therapeutic potential of RAS antagonism: RAS blockade l- its disease progression of type 2 diabetes mellitus and impaired glucose tolerance, and may also protect against pancreatic in ammation. Highlighting the role local renin-angiotensin systems (RAS) play in pancreatic disease, this review presents the latest research advances in the field. These findings suggest both preventative measures and treatment for pancreatic disease. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Nº de ref. del artículo: 9789400733329
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The Renin-Angiotensin System: Current Research Progress in The Pancreas: The RAS in the Pancreas (Advances in Experimental Medicine and Biology, 690)
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The Renin-Angiotensin System: Current Research Progress in The Pancreas: The RAS in the Pancreas (Advances in Experimental Medicine and Biology, 690)
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The Renin-Angiotensin System: Current Research Progress in The Pancreas
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Springer Netherlands Nov 2012, 2012
ISBN 10: 9400733321
ISBN 13: 9789400733329
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The human pancreas has vital roles in the regulation of glucose homeostasis and digestion and its dysfunction leads to pancreatic disease as diabetes and pancreatitis. Recent researches have highlighted the novel roles of a local renin-angiotensin system (RAS) in the pancreas and its clinical relevances; its inapprporiate activation leads to pancreatic endocrine and exocrine disease, notably type 2 diabetes. As such, manipulation of the overactive RAS may improve pancreatic islet cell function, cell mass and insulin sensitivity, as well as enhancing the growth and differentiation of pancreatic stem cells. Blockade of the RAS may be protective against pancreatitis and pancreatic cancer. The research outcome of current progress on the RAS in the pancreas should provide an alternative approach to preventing and treating, as well as curing pancreatic disease. This book discusses the progress of research on the renin-angiotensin system in the pancreas from the science to the bedside, providing a timely review of this expanding area. It consists of ten interrelated chapters covering subjects as: -Structure, physiology and disease of the pancreas-Biochemistry and physiology of the pancreatic renin-angiotensin system-RAS in diabetes, stem cells and pancreatitisThis book is of special value to basic and clinical scientists, clinicians, graduate students, as well as novices in this field. 224 pp. Englisch. Nº de ref. del artículo: 9789400733329
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The Renin-Angiotensin System: Current Research Progress in The Pancreas
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Springer Netherlands, 2012
ISBN 10: 9400733321
ISBN 13: 9789400733329
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Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A topical, timely and focussed book in the field A book written by a single author who contributes significantly to the fieldA selected compilation of TEN selected chapters that critically appraise the contemporary research advance in the field A critical . Nº de ref. del artículo: 5826375
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Renin-angiotensin System : Current Research Progress in the Pancreas - the Ras in the Pancreas
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The Renin-Angiotensin System: Current Research Progress in The Pancreas: The RAS in the Pancreas (Advances in Experimental Medicine and Biology, 690)
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The Renin-angiotensin System: Current Research Progress in the Pancreas. The Ras in the Pancreas.
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Condición: New. Highlighting the role local renin-angiotensin systems (RAS) play in pancreatic disease, this review presents the latest research advances in the field. These findings suggest both preventative measures and treatment for pancreatic disease. Series: Advances in Experimental Medicine and Biology. Num Pages: 208 pages, biography. BIC Classification: MBGR; MFG; MJGD; MJH. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 12. Weight in Grams: 349. . 2012. Paperback. . . . . Nº de ref. del artículo: V9789400733329
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The Renin-Angiotensin System: Current Research Progress in The Pancreas
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Springer Netherlands, Springer Netherlands Nov 2012, 2012
ISBN 10: 9400733321
ISBN 13: 9789400733329
Nuevo
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Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The human pancreas consists of two organs in one: the exocrine gland made up of pancreatic acinar cells and duct cells that produce digestive enzymes and sodium bicarbonate, respectively; the endocrine gland made up of four islet cells, namely alpha-, beta-, delta- and PP-cells that produce glucagon, insulin, somatostatin and pancreatic polypeptide, respectively. While the physiological role of exocrine p- creas is to secrete digestive enzyme responsible for our normal digestion, absorption and assimilation of nutrients, the endocrine pancreas is to secrete islet peptide h- mones maintaining our glucose homeostasis. The pancreatic functions are nely regulated by neurocrine, endocrine, paracrine and/or intracrine mechanisms. Thus, dysregulation of these pathways should have signi cant impacts on our health and disease. Nevertheless, the underlying mechanisms by which pancreatic functions are regulated remain poorly understood. Recent basic science and clinical studies con rm myriad physiological and pathophysiological roles of the tissue renin-angiotensin systems (RAS). Of parti- lar interest is the recent identi cation of a local and functional RAS in the pancreas, which in uences both its exocrine and endocrine function. Its role in the pat- genesis of pancreatic diseases including diabetes and pancreatitis is increasingly recognized, as is the therapeutic potential of RAS antagonism: RAS blockade l- its disease progression of type 2 diabetes mellitus and impaired glucose tolerance, and may also protect against pancreatic in ammation.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 224 pp. Englisch. Nº de ref. del artículo: 9789400733329
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