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The Renin-Angiotensin System: Current Research Progress in The Pancreas : The RAS in the Pancreas: 690 (Advances in Experimental Medicine and Biology) - Tapa dura
Sinopsis
PART I: THE PANCREAS.- 1. Overview of the Pancreas.- 1.1. Structure of the pancreas.- 1.2. Development of the pancreas.- 1.3. Molecular hierarchy of pancreatic development.- 2. Physiology of the Pancreas.- 2.1. Exocrine-endocrine axis.- 2.2. Pancreatic acinar cells.- 2.3. Pancreatic duct cells.- 2.4. Pancreatic islet cells.- 3. Common Pancreatic Disease.- 3.1. Pancreatitis.- 3.2. Cystic fibrosis.- 3.3. Pancreatic cancer.- 3.4. Diabetes mellitus.- PART II: THE RENIN-ANGIOTENSIN SYSTEM (RAS).- 4. Circulating RAS.- 4.1. Definition of circulating RAS4.3. Angiotensinogen.- 4.3. Angiotensin-generating enzymes.- 4.4. Angiotensin and (pro)renin receptors.- 5. Local RAS.- 5.1. Definition of the local RAS.- 5.2. Local RAS in carotid body5.3. Local RAS in liver.- 5.4. Local RAS in intestine.- 6. Pancreatic RAS.- 6.1. Acinar cell RAS.- 6.2. Ductal cell RAS.- 6.3. Stellate cell RAS.- 6.4. Islet cell RAS.- PART III: RESEARCH PROGRESS OF THE RAS IN PANCREAS.- 7. Basic Techniques for Pancreatic Research.- 7.1. Cell models.- 7.2. Animal models.- 7.3. Islet and acinar cell isolation.- 7.4. Islet transplantation.- 7.5. Expression and functional studies.- 8. Current Research of the RAS in Diabetes Mellitus .- 8.1. Basic studies of the RAS in T2DM.- 8.2. Clinical studies of the RAS in T2DM.- 8.3. Current research on the RAS-vitamin D-T2DM axis.- 8.4. Current research on the RAS-GLP1-T2DM axis.- 9. Current Research of the RAS in Pancreatic Stem Cells.- 9.1. Source of pancreatic stem cells.- 9.2. Current research on pancreatic stem cells.- 9.3. Current research of the RAS on stem cells.- 9.4. Current research of the RAS on pancreatic stem cells.- 9.5. Limitations and future directions.- 10. Current Research of the RAS in Pancreatitis and Pancreatic Cancer .- 10.1. Basic studies of the RAS in pancreatitis.- 10.2. Current in vivo research of the RAS on pancreatitis.- 10.3. Current in vitro research of the RAS on pancreatitis.- 10.4. Current research of the RAS on pancreatic cancer.- Subject Index.- Epilogue by Per-Ola Carlsson (Sweden) and Jan Danser (Netherlands).
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De la contraportada
The human pancreas has vital roles in the regulation of glucose homeostasis and digestion and its dysfunction leads to pancreatic disease as diabetes and pancreatitis. Recent researches have highlighted the novel roles of a local renin-angiotensin system (RAS) in the pancreas and its clinical relevances; its inapprporiate activation leads to pancreatic endocrine and exocrine disease, notably type 2 diabetes. As such, manipulation of the overactive RAS may improve pancreatic islet cell function, cell mass and insulin sensitivity, as well as enhancing the growth and differentiation of pancreatic stem cells. Blockade of the RAS may be protective against pancreatitis and pancreatic cancer. The research outcome of current progress on the RAS in the pancreas should provide an alternative approach to preventing and treating, as well as curing pancreatic disease. This book discusses the progress of research on the renin-angiotensin system in the pancreas from the science to the bedside, providing a timely review of this expanding area. It consists of ten interrelated chapters covering subjects as: Structure, physiology and disease of the pancreas Biochemistry and physiology of the pancreatic renin-angiotensin system RAS in diabetes, stem cells and pancreatitisThis book is of special value to basic and clinical scientists, clinicians, graduate students, as well as novices in this field.
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The Renin-Angiotensin System: Current Research Progress in the Pancreas: The Ras in the Pancreas
Publicado por
SPRINGER NATURE, 2010
ISBN 10: 9048190592
ISBN 13: 9789048190591
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Librería: Buchpark, Trebbin, Alemania
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The Renin-Angiotensin System: Current Research Progress in The Pancreas
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Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A topical, timely and focussed book in the field A book written by a single author who contributes significantly to the fieldA selected compilation of TEN selected chapters that critically appraise the contemporary research advance in the field A critical . Nº de ref. del artículo: 5822494
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The Renin-Angiotensin System: Current Research Progress in The Pancreas: The RAS in the Pancreas (Advances in Experimental Medicine and Biology, Vol. ... in Experimental Medicine and Biology, 690)
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The Renin-Angiotensin System: Current Research Progress in the Pancreas: The Ras in the Pancreas
Publicado por
SPRINGER NATURE Sep 2010, 2010
ISBN 10: 9048190592
ISBN 13: 9789048190591
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Tapa dura
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
Calificación del vendedor: 5 de 5 estrellas
Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The human pancreas has vital roles in the regulation of glucose homeostasis and digestion and its dysfunction leads to pancreatic disease as diabetes and pancreatitis. Recent researches have highlighted the novel roles of a local renin-angiotensin system (RAS) in the pancreas and its clinical relevances; its inapprporiate activation leads to pancreatic endocrine and exocrine disease, notably type 2 diabetes. As such, manipulation of the overactive RAS may improve pancreatic islet cell function, cell mass and insulin sensitivity, as well as enhancing the growth and differentiation of pancreatic stem cells. Blockade of the RAS may be protective against pancreatitis and pancreatic cancer. The research outcome of current progress on the RAS in the pancreas should provide an alternative approach to preventing and treating, as well as curing pancreatic disease. This book discusses the progress of research on the renin-angiotensin system in the pancreas from the science to the bedside, providing a timely review of this expanding area. It consists of ten interrelated chapters covering subjects as: -Structure, physiology and disease of the pancreas-Biochemistry and physiology of the pancreatic renin-angiotensin system-RAS in diabetes, stem cells and pancreatitisThis book is of special value to basic and clinical scientists, clinicians, graduate students, as well as novices in this field. 208 pp. Englisch. Nº de ref. del artículo: 9789048190591
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Renin-Angiotensin System : Current Research Progress in the Pancreas: The RAS in the Pancreas
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The Renin-Angiotensin System: Current Research Progress in the Pancreas : The Ras in the Pancreas
Librería: AHA-BUCH GmbH, Einbeck, Alemania
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Buch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - The human pancreas has vital roles in the regulation of glucose homeostasis and digestion and its dysfunction leads to pancreatic disease as diabetes and pancreatitis. Recent researches have highlighted the novel roles of a local renin-angiotensin system (RAS) in the pancreas and its clinical relevances; its inapprporiate activation leads to pancreatic endocrine and exocrine disease, notably type 2 diabetes. As such, manipulation of the overactive RAS may improve pancreatic islet cell function, cell mass and insulin sensitivity, as well as enhancing the growth and differentiation of pancreatic stem cells. Blockade of the RAS may be protective against pancreatitis and pancreatic cancer. The research outcome of current progress on the RAS in the pancreas should provide an alternative approach to preventing and treating, as well as curing pancreatic disease. This book discusses the progress of research on the renin-angiotensin system in the pancreas from the science to the bedside, providing a timely review of this expanding area. It consists of ten interrelated chapters covering subjects as: -Structure, physiology and disease of the pancreas-Biochemistry and physiology of the pancreatic renin-angiotensin system-RAS in diabetes, stem cells and pancreatitisThis book is of special value to basic and clinical scientists, clinicians, graduate students, as well as novices in this field. Nº de ref. del artículo: 9789048190591
Cantidad disponible: 2 disponibles
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The Renin-Angiotensin System: Current Research Progress in The Pancreas: The RAS in the Pancreas (Advances in Experimental Medicine and Biology, Vol. ... in Experimental Medicine and Biology, 690)
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The Renin-Angiotensin System
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The Renin-Angiotensin System: Current Research Progress in The Pancreas: The RAS in the Pancreas (Advances in Experimental Medicine and Biology, Vol. ... in Experimental Medicine and Biology, 690)
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