The Interface Between Innate and Acquired Immunity: 266 (Current Topics in Microbiology and Immunology, 266) - Tapa dura

 
9783540428947: The Interface Between Innate and Acquired Immunity: 266 (Current Topics in Microbiology and Immunology, 266)
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ISBN 10: 3540428941 ISBN 13: 9783540428947
Editorial: Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 2002

Sinopsis

The topics of this volume include regulation of the helper T cell subset involved in inflammatory responses versus the subset of helper T cells involved in promoting B cells responses in humoral immunity, the regulation of T cell activity in inflammatory and autoimmune disease by the tumor necrosis factor superfamily of receptors and their ligands, the wide array of inhibitory and activating receptor that regulate natural killer cell function, phylogeny of Ig gene superfamily members linked to the major histocompatibility gene complex, the IgFc receptor family and a newly discovered family of Fc receptor homologs, the role of complement in linking innate and adaptive immunity, and manipulation of the potential for plants to protect themselves by innate and adaptive responses to viruses.

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Reseña del editor

All multicellular organisms may possess innate immunity mediated by defense mechanisms with which the organism is born. In recent years much has been learned about the diversity of innate immune mechanisms. A large array of naturally produced antimicrobial peptides has been de­ fined. A variety of cell surface receptors that recognize common patterns displayed by infectious organisms have been identified along with the intracellular pathways that these receptors use to activate cellular defense functions. Cell surface receptors on natural killer (NK) cells have been shown to sense microbial invasion in neighboring cells, thereby setting into motion their elimination by cy­ totoxic mechanisms. Other receptors have been found to facilitate phagocytosis and intracellular killing of microbes by phagocytic cells. These and other natural defense mechanisms have traditionally been viewed as the first line of body defense in vertebrate species that also possess the capacity for acquired or adaptive immunity. Sharks and all of the other jawed vertebrates generate large repertoires of T and B lymphocyte clones that display different antigen­ specific receptors in the form ofT cell receptors (TCR) and immunoglobulins (Ig) that allow them to recognize and respond to antigens in collaboration with antigen-present­ ing cells. Memory T and B cells are then generated to allow faster and heightened cellular and humoral immune re­ sponses on secondary antigen encounter. In recent years it has also become obvious that innate immune responses can directly influence adaptive immune responses in ways that will enhance body defense.

Reseña del editor

The topics of this volume include regulation of the helper T cell subset involved in inflammatory responses versus the subset of helper T cells involved in promoting B cells responses in humoral immunity, the regulation of T cell activity in inflammatory and autoimmune disease by the tumor necrosis factor superfamily of receptors and their ligands, the wide array of inhibitory and activating receptor that regulate natural killer cell function, phylogeny of Ig gene superfamily members linked to the major histocompatibility gene complex, the IgFc receptor family and a newly discovered family of Fc receptor homologs, the role of complement in linking innate and adaptive immunity, and manipulation of the potential for plants to protect themselves by innate and adaptive responses to viruses.

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Año de publicación
2002
Idioma
Inglés
ISBN 10 
3540428941
ISBN 13 
9783540428947
Encuadernación
Tapa dura
Número de páginas
131
Editor
Cooper M.D., Koprowski H.
Contacto del fabricante
ROXIO
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Friedrich-Karl-Str. 9
Hamburg
22391
Alemania

Otras ediciones populares con el mismo título

9783662047019: The Interface Between Innate and Acquired Immunity

Edición Destacada

ISBN 10:  3662047012 ISBN 13:  9783662047019
Editorial: Springer, 2012
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