The Inflammasome: Methods and Protocols: 1040 (Methods in Molecular Biology) - Tapa blanda

 
9781493960118: The Inflammasome: Methods and Protocols: 1040 (Methods in Molecular Biology)
Tapa blanda
ISBN 10: 1493960113 ISBN 13: 9781493960118
Editorial: Humana, 2016

Sinopsis

Inflammasomes have a seemingly simple architecture. A sensor molecule of the NLR or PYHIN protein family recruits the common adapter molecule apoptosis-associated speck-like protein containing a CARD (ASC). Even so, inflammasome activation is highly regulated at multiple steps and precise details of how inflammasomes are activated at the molecular level remain largely unknown. In The Inflammasome: Methods and Protocols, expert researchers in the field detail methods and protocols to study multiple aspects of inflammasome function. These methods include the generation of inflammasome stimuli, perturbance of cellular homeostasis, assessment of ASC speck formation, monitoring of caspase-1 activity and processing, activation of IL-1β cytokines, and analysis of inflammasome assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

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De la contraportada

 Inflammasomes have a seemingly simple architecture. A sensor molecule of the NLR or PYHIN protein family recruits the common adapter molecule apoptosis-associated speck-like protein containing a CARD (ASC). Even so, inflammasome activation is highly regulated at multiple steps and precise details of how inflammasomes are activated at the molecular level remain largely unknown. In The Inflammasome: Methods and Protocols, expert researchers in the field detail methods and protocols to study multiple aspects of inflammasome function. These methods include the generation of inflammasome stimuli, perturbance of cellular homeostasis, assessment of ASC speck formation, monitoring of caspase-1 activity and processing, activation of IL-1ß cytokines, and analysis of inflammasome assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

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Editorial
Humana
Año de publicación
2016
Idioma
Inglés
ISBN 10 
1493960113
ISBN 13 
9781493960118
Encuadernación
Tapa blanda
Número de páginas
240
Editor
De Nardo Christine M., Latz Eicke
Contacto del fabricante
ProductSafety@springernature.com
ProductSafety@springernature.com

Poststr. 9
Darmstadt
64293
Alemania

Otras ediciones populares con el mismo título

9781627035224: The Inflammasome: Methods and Protocols: 1040 (Methods in Molecular Biology, 1040)

Edición Destacada

ISBN 10:  1627035222 ISBN 13:  9781627035224
Editorial: Humana, 2013
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