Bioconductor Case Studies (Use R!)

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9780387772394: Bioconductor Case Studies (Use R!)

Book by Hahne Florian Huber Wolfgang Gentleman Robert Falc

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From the reviews:

"This work has extended R substantially and is an important tool for research. … All the code, including solutions to the exercises, is available for downloading on the Web and-this is well worth mentioning-it runs straight out of the box…. The book describes various analysis, provides the code for them and discusses the output. This makes for an easy read and anyone who works through the book will gain confidence that they can carry out analysis on their own data. The discussion of analysis is generally sound and practical. In particular the interpretation of the results of clustering is more sensible then you often see…. This book is strongly recommended for learning more about Bioconductor." (Antony Unwin, Journal of Statistical Software, January 2009, Volume 29, Book Review 1).

"The readership of this book will be specialized but the text deserves to be read more widely within the statistics and computer science communities as there is much to interest the inquiring mind. … Exercises for private study and their solutions are provided as an integral part of the text. "(C.M. O’Brien, International Statistical Review, 2009, 77, 1)

“One of the great advantages of the R language is its dynamic nature, where code and other resources are continuously generated in order to address novel analytical challenges. Microarray gene expression data present such a challenge, and the Bioconductor project has risen over the years to become the foremost central repository of R-implemented approaches for such data. However, while individual packages within Bioconductor are usually well documented, it is often hard to know which packages to use in what circumstances, especially when tools from several packages are best used in concert. This text aims to fill that void by offering a collection of case studies derived from the authors’ own Bioconductor courses, covering the topics of processing raw intensities; correcting for background noise and variation across chips; differential expression analysis; machine learning for clustering and classification; graph creation; and gene set enrichment. …All in all, this text is an excellent, well-written reference for many of the common tasks that arise during the analysis of microarray gene expression datasets, as implemented by Bioconductor. It is well worth the modest sum required for its purchase.” (The American Statistician, May 2010, Vol. 64, No. 2)

Reseña del editor:

Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include: (1) import and preprocessing of data from various sources; (2) statistical modeling of differential gene expression; (3) biological metadata; (4) application of graphs and graph rendering; (5) machine learning for clustering and classification problems; (6) gene set enrichment analysis.

Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table.

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Hahne, Florian, Huber, Wolfgang, Gentlem
Editorial: Springer (2017)
ISBN 10: 0387772391 ISBN 13: 9780387772394
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Florian Hahne, Wolfgang Huber, Robert Gentleman
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ISBN 10: 0387772391 ISBN 13: 9780387772394
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Descripción Springer-Verlag New York Inc., United States, 2008. Paperback. Estado de conservación: New. 2008.. 234 x 155 mm. Language: English . Brand New Book ***** Print on Demand *****. Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include: (1) import and preprocessing of data from various sources; (2) statistical modeling of differential gene expression; (3) biological metadata; (4) application of graphs and graph rendering; (5) machine learning for clustering and classification problems; (6) gene set enrichment analysis. Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table. Nº de ref. de la librería AAV9780387772394

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Florian Hahne, Wolfgang Huber, Robert Gentleman
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ISBN 10: 0387772391 ISBN 13: 9780387772394
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Descripción Springer-Verlag New York Inc., United States, 2008. Paperback. Estado de conservación: New. 2008.. 234 x 155 mm. Language: English . Brand New Book ***** Print on Demand *****.Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include: (1) import and preprocessing of data from various sources; (2) statistical modeling of differential gene expression; (3) biological metadata; (4) application of graphs and graph rendering; (5) machine learning for clustering and classification problems; (6) gene set enrichment analysis. Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table. Nº de ref. de la librería AAV9780387772394

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Florian Hahne, Wolfgang Huber, Robert Gentleman
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ISBN 10: 0387772391 ISBN 13: 9780387772394
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Descripción Springer-Verlag New York Inc., United States, 2008. Paperback. Estado de conservación: New. 2008.. 234 x 155 mm. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include: (1) import and preprocessing of data from various sources; (2) statistical modeling of differential gene expression; (3) biological metadata; (4) application of graphs and graph rendering; (5) machine learning for clustering and classification problems; (6) gene set enrichment analysis. Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table. Nº de ref. de la librería LIE9780387772394

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Florian Hahne
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Descripción Springer-Verlag New York Inc., 2008. PAP. Estado de conservación: New. New Book.Shipped from US within 10 to 14 business days.THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Nº de ref. de la librería IP-9780387772394

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FLORIAN HAHNE
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Descripción Springer, 2008. Paperback. Estado de conservación: NEW. 9780387772394 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Nº de ref. de la librería HTANDREE0274513

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Florian Hahne; Wolfgang Huber; Robert Gentleman
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