First Signals (Paperback)

John Tyler Bonner

12 valoraciones de Goodreads

Idioma: inglés

Editorial: Princeton University Press, New Jersey, 2001

0691070385 / 9780691070384

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Paperback. The enormous recent success of molecular developmental biology has yielded a vast amount of new information on the details of development. So much so that we risk losing sight of the underlying principles that apply to all development. To cut through this thicket, John Tyler Bonner ponders a moment in evolution when development was at its most basic - the moment when signaling between cells began. Although multicellularity arose numerous times, most of those events happened many millions of years ago. Many of the details of development that we see today, even in simple organisms, accrued over a long evolutionary timeline, and the initial events are obscured. The relatively uncomplicated and easy-to-grow cellular slime molds offer a unique opportunity to analyze development at a primitive stage and perhaps gain insight into how early multicellular development might have started. Through slime molds, Bonner seeks a picture of the first elements of communication between cells. He asks what we have learned by looking at their developmental biology, including recent advances in our molecular understanding of the process.He then asks what is the most elementary way that polarity and pattern formation can be achieved. To find the answer, he uses models, including mathematical ones, to generate insights into how cell-to-cell cooperation might have originated. Students and scholars in the blossoming field of the evolution of development, as well as evolutionary biologists generally, will be interested in what Bonner has to say about the origins of multicellular development - and thus of the astounding biological complexity we now observe - and how best to study it. This work investigates a moment in evolution when development was at its most basic - the moment when signalling between cells began. Using slime mould as an example, the author seeks to analyze development at a primitive stage and gain an insight into how early multicellular development began. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. …

N° de ref. del artículo 9780691070384

Título
First Signals (Paperback)
Autor
John Tyler Bonner
Editorial
Princeton University Press, New Jersey
Año de publicación
2001
Estado
new
Encuadernación
Paperback
Idioma
inglés
ISBN 10
0691070385
ISBN 13
9780691070384
Edición
1ª Edición

CitiRetail

Stevenage, Reino Unido

Vendedor de 5 estrellas

Vendedor de IberLibro desde 29 de junio de 2022

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