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Añadir al carritoTaschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - The accumulation of white blood cells is a hallmark of inflammation. The penetra tion through the vessel walls and the infiltration around the inflammatory stimulus is a complex process which involves active adherence and directed migration of the inflammatory cells. Chemotactic factors stimulate both adherence and migration. Technical tools such as the Boyden chamber [1] made it possible to study leukocyte migration in vitro. This technique allows differentiation between migration direct ed towards a chemotactic stimulus and non-directed migration. Until a decade ago only two naturally occurring molecules had been clearly iden tified as potent chemotactic attractants of neutrophilic granulocytes. They were the split product of the fifth complement component C5a [2] and the arachidonic acid metabolite leukotriene B4 [3]. In 1986, a novel human monocyte-derived chemo taxin attracting neutrophilic granulocytes with a similar potency was found [4]. This report was quickly confirmed by several groups [5-8]. The new factor was purified, cloned and sequenced [9, 10]. The term 'interleukin 8' (IL-8) replaced the various names proposed previously [4-8]. Sequence data revealed that IL-8 belonged to a large family of chemotactic cytokines, now called 'chemokines' [11]. Four subfamilies were distinguished on the basis of the number and position of the first cysteine residues. They are desig nated accordingly as C, CC, CXC and CX C chemokines [11-13]. The number of 3 human chemokines identified so far is close to 40 [11-13].
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Añadir al carritoTaschenbuch. Condición: Neu. Chemokines and Skin | Kownatzki (u. a.) | Taschenbuch | Progress in Inflammation Research | xiii | Englisch | 2012 | Birkhäuser | EAN 9783034897976 | Verantwortliche Person für die EU: Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Idioma: Inglés
Publicado por Birkhäuser Basel Okt 2012, 2012
ISBN 10: 3034897979 ISBN 13: 9783034897976
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Añadir al carritoTaschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The accumulation of white blood cells is a hallmark of inflammation. The penetra tion through the vessel walls and the infiltration around the inflammatory stimulus is a complex process which involves active adherence and directed migration of the inflammatory cells. Chemotactic factors stimulate both adherence and migration. Technical tools such as the Boyden chamber [1] made it possible to study leukocyte migration in vitro. This technique allows differentiation between migration direct ed towards a chemotactic stimulus and non-directed migration. Until a decade ago only two naturally occurring molecules had been clearly iden tified as potent chemotactic attractants of neutrophilic granulocytes. They were the split product of the fifth complement component C5a [2] and the arachidonic acid metabolite leukotriene B4 [3]. In 1986, a novel human monocyte-derived chemo taxin attracting neutrophilic granulocytes with a similar potency was found [4]. This report was quickly confirmed by several groups [5-8]. The new factor was purified, cloned and sequenced [9, 10]. The term 'interleukin 8' (IL-8) replaced the various names proposed previously [4-8]. Sequence data revealed that IL-8 belonged to a large family of chemotactic cytokines, now called 'chemokines' [11]. Four subfamilies were distinguished on the basis of the number and position of the first cysteine residues. They are desig nated accordingly as C, CC, CXC and CX C chemokines [11-13]. The number of 3 human chemokines identified so far is close to 40 [11-13]. 156 pp. Englisch.
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Añadir al carritoCondición: New. Print on Demand pp. 156.
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Añadir al carritoKartoniert / Broschiert. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Chemokines: Attraction of dendritic cells and role in tumor immunobiology.- Chemokine receptors.- Regulation of gene expression of chemokines and their receptors.- Chemokines and T lymphocytes.- Chemokines and mast cells.- Chemokines and eosinophils.- CXC-c.
Idioma: Inglés
Publicado por Birkhäuser, Birkhäuser Okt 2012, 2012
ISBN 10: 3034897979 ISBN 13: 9783034897976
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Añadir al carritoTaschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Chemokines: Attraction of dendritic cells and role in tumor immunobiology.- Chemokine receptors.- Regulation of gene expression of chemokines and their receptors.- Chemokines and T lymphocytes.- Chemokines and mast cells.- Chemokines and eosinophils.- CXC-chemokines - autocrine growth factors for melanoma and epidermoid carcinoma cells.- Expression of chemokines in dermatoses.Springer Nature c/o IBS, Benzstrasse 21, 48619 Heek 156 pp. Englisch.