9780199631377 - The Biology and Clinical Applications of Interleukin-2 (2 resultados)

Hardcover. Condición: Near Fine. No Jacket. 0199631379. Pictorial board hardcover, no creases or inscriptions. 144 pages, index, illustrated with charts, tables and diagrams. Presents the proceedings of the international symposium held at the University of Sheffield in 1989. The molecular structure of IL-2 and its receptor subunits provide a basis for understanding lymphocyte activation by IL-2 and the generation of effector cells capable of mediating cytotoxicity towards tumours. Discusses molecular aspects of cell signalling, allowing speculation of the in vivo pathways of activation likely to be important in determining clinical responses. Attention has focussed on the use of cytokines, particularly IL-2, for the treatment of cancer. The results from clinical trials using IL-2 and adoptive cellular therapy provide a clear account of the clinical progress, and of the problems encountered in attempting to improve the therapeutic benefit of IL-2. The importance of mechanisms which subverse IL-2 responses is also given. Contents clean, tight and bright. Book.

Hardcover. Condición: Very Good. 1st Edition.