Springer vienna springer sep 2012 (38 resultados)

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -neoessity for making it. Yet, clearly, the problem of development is largely one of filling 'the vacuum between determinant and character' (DARLINGTON 1951). Nowadays the chromosome theory can be presented in much greater detail and with utter confidence, but its two main features remain the same. However, while the role of the chromosomes in heredity and development has been appreciated for a long time, the manner in which they perform their genetic and epigenetic functions has become amenable to critical investigation only in recent years. There is, therefore, still an unmistakable tendency to think of chromosomes in terms of the discrete threads of cell division and, in keeping with this conception, the chromosome cycle is gen erally considered in relation to the microscopically visible changes in morphology which occur during the mechanically active phases of mitosis and meiosis. Chromosome phenotype, however, changes not only during division but throughout the cell cycle. The changes which occur during interphase are, of course, scarcely revealed in morphological modifications of the restless 'resting' nucleus. Consequently they are less obvious and correspondingly less amenable to investigation. This accounts for the concentration on the countable karyotype, with its visible properties of pairing and pycnosity, and the measurable movements of separation and segregation. 136 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Progress in basic and clinical immunology within the last two decades has provided profound insight into the immune system and its role in preventing endogenous and exogenous damage. In contrast, disbalances within this system can result in autoimmune disorders which may affect diverse organs and result in distinct clinical pictures. In many of these, however, the individual etiopathogenetic mechanisms are poorly understood and even more their clinical symptoms are hard to treat.The book offers insight into basic mechanisms of autoimmune disorders. It includes neurological, gastrointestinal, ophthalmological and skin diseases as well as current and future therapeutic options including immunomodulatory drugs and different vaccination strategies. By addressing diverse organ systems, both singular and shared features are elaborated. Thus an exchange of ideas is intended across research on single organ systems within a truly interdisciplinary setting. 196 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Sl'colld International Symposium on Basic Environmental Problems of Man in Space was held 14-18 June 1965 at Unesco House, Paris. It was or ganized by thf' International Astronautical Federation and the International Academy of Astronautics with the support and cooperation of Unesco, the International Atomic EUl'rgy Agency, the World Health Organization, the World MeteOl'ological Ol'ganization. and the International Telecommunication Union. Thc Sympmliulll was devotcd to four main problem areas, viz. (1) ecophysi ology, (2) psychophysiology and engineering psychology, (3) special man machine probh~ms. and (4-) biot,echnology. A total of 30 papers-all by special invitation--wpl'(' PI'PRf'lltl'd during ) half-day working sessions. Eight ofthe papers were from the P,S,A' S fl'Olll the U,S,S,R. , and 14from other countries. The pres entations includcd foUl' ~,!pneral review papers. The working languages were English, Russian. ami Fl't'Ilch, This volul1H' contaiwl aH the papers of the Symposium and also reports the discussionK foHowing individual papers. Papers in the Russian language appeal' in full also in English, Abstracts appear in all three languages, trans lations being ~;upplipd by eOUl'tesy of Unesco. For the reporting of discussions the following sysü'lll wal' used, Each person asking a question or making a comment from the flool' was given a 'question and answer' form immediately after he had finished sppaking. Thc questioner and the session speaker were asked to writp down thpir qtlPstions. answers or comments at their earliest conwnience and to 'PÜII'1l thp completed form the same day if possible. 540 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -text 148 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The Sl'colld International Symposium on Basic Environmental Problems of Man in Space was held 14-18 June 1965 at Unesco House, Paris. It was or ganized by thf' International Astronautical Federation and the International Academy of Astronautics with the support and cooperation of Unesco, the International Atomic EUl'rgy Agency, the World Health Organization, the World MeteOl'ological Ol'ganization. and the International Telecommunication Union. Thc Sympmliulll was devotcd to four main problem areas, viz. (1) ecophysi ology, (2) psychophysiology and engineering psychology, (3) special man machine probh~ms. and (4-) biot,echnology. A total of 30 papers-all by special invitation--wpl'(' PI'PRf'lltl'd during ) half-day working sessions. Eight ofthe papers were from the P,S,A' S fl'Olll the U,S,S,R. , and 14from other countries. The pres entations includcd foUl' ~,!pneral review papers. The working languages were English, Russian. ami Fl't'Ilch, This volul1H' contaiwl aH the papers of the Symposium and also reports the discussionK foHowing individual papers. Papers in the Russian language appeal' in full also in English, Abstracts appear in all three languages, trans lations being ~;upplipd by eOUl'tesy of Unesco. For the reporting of discussions the following sysü'lll wal' used, Each person asking a question or making a comment from the flool' was given a 'question and answer' form immediately after he had finished sppaking. Thc questioner and the session speaker were asked to writp down thpir qtlPstions. answers or comments at their earliest conwnience and to 'PÜII'1l thp completed form the same day if possible.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 540 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Most organic molecules retain their integrity when dissolved, and even though in such cases the effects exerted by solvents are, in the language of the coordination chemist, of the 'outer sphere' kind, the choice of solvent can be critical to the successful outcome of an operation or preparation. Solubilities of reactants and products must be taken into account, and even if the organic principals in the reactions retain their integrity, many of the reagents are electrolytes, and their state of aggregation will affect their reactivity. In testifying to the importance of understanding solute-solvent interactions I draw attention to a large class of inorganic species for which the involvement in the chemical and physical properties by the solvent is even more deeply seated. It is comprised by the large body of metal atoms in low oxidation states for which solvent molecules intervene as reagents. At the same time, because the ions carry charges, the effects arising from outer sphere interactions are usually greater than they are for neutral molecules. To cite an example: when FeCb(s) is dissolved in water to form a dilute - say O. OlO- solution there is a complete reorganization of the coordination sphere of the cation. Whereas in the solid each cation is surrounded by six chloride ions, in the solution the dominant form is [Fe(H20)6]3+ followed by [Fe(H20)sCI]2+, [Fe(H20)4CI2]+, etc. in rapidly decreasing abundance. 236 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As an addition to the European postgraduate training system for young neurosurgeons we began to publish in 1974 this series of Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association of Neurosurgical Societies. This series was first discussed in 1972 at a combined meeting of the Italian and German Neurosurgical Societies in Taormina, the founding fathers of the series being Jean Brihaye, Bernard Pertuiset, Fritz Loew and of European co Hugo Krayenbtihl. Thus were established the principles operation which have been born from the European spirit, flourished in the European Association, and have throughout been associated with this series. The fact that the English language is well on the way to becoming the international medium at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contributions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publi cation of any volume. Our series is not intended to compete with the publications of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fields and constitute the first part of each volume. 272 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is well known that estrogen is 'somehow' a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen's neuroprotective activities in the brain with a special emphasis on neurodegenerative disorders such as Alzheimer's Disease. The focus is (1) to describe the biochemical, molecular, and cellular basis of the protective activity of estrogen and (2) to transfer this knowledge into the hospitals by discussing preventive and therapeutic approaches such as estrogen replacement therapy for post-menopausal women.Besides up-to-date information on estrogen and the brain, this book explains in a highly understandable manner molecular and cellular techniques by which basic data have been collected. The reader, which may include the professional specialist as well as the interested non-specialist, will also gain insight into the scientific transfer process of knowledge from basic science to the clinical situation and therefore 'from bench to bed'. 252 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book summarizes the research of more than a decade. Its early motivation dates back to the eighties and to the memorable talks Dr. C. Moglestue (FHG Freiburg) gave on his Monte-Carlo solutions of the Boltzmann transport equation at the NASECODE conferences in Ireland. At that time numerical semiconductor device modeling basically implied the application of the drift-diffusion model. On the one hand, those talks clearly showed the potential of the Monte-Carlo model for an accurate description of many important transport issues that cannot adequately be addressed by the drift-diffusion approximation. On the other hand, they also clearly demonstrated that at that time only very few experts were able to extract useful results from a Monte-Carlo simulator. With this background, Monte-Carlo research activities were started in 1986 at the University of Aachen (RWTH Aachen), Germany. Different to many other Monte-Carlo research groups, the Monte-Carlo research in Aachen took place in an environment of active drift-diffusion and hydrodynamic model development. 280 pp. Englisch.…

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The central subject of the book is the generalization of Loewy's decomposition - originally introduced by him for linear ordinary differential equations - to linear partial differential equations. Equations for a single function in two independent variables of order two or three are comprehensively discussed. A complete list of possible solution types is given. Various ad hoc results available in the literature are obtained algorithmically. The border of decidability for generating a Loewy decomposition are explicitly stated. The methods applied may be generalized in an obvious way to equations of higher order, in more variables or systems of such equations. 248 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this first volume of the series Update in Plastic Surgery, internationally acknowledged experts give an up-to-date view of the clinical possibilities in plastic surgery which result from video-assisted microsurgery with the endoscope. Advantages and disadvantages are discussed, and reasons are presented why it can be assumed that this technique will be the standard in plastic surgery within a few years. 156 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -It is well known that estrogen is 'somehow¿ a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen¿s neuroprotective activities in the brain with a special emphasis on neurodegenerative disorders such as Alzheimer¿s Disease. The focus is (1) to describe the biochemical, molecular, and cellular basis of the protective activity of estrogen and (2) to transfer this knowledge into the hospitals by discussing preventive and therapeutic approaches such as estrogen replacement therapy for post-menopausal women.Besides up-to-date information on estrogen and the brain, this book explains in a highly understandable manner molecular and cellular techniques by which basic data have been collected. The reader, which may include the professional specialist as well as the interested non-specialist, will also gain insight into the scientific transfer process of knowledge from basic science to the clinical situation and therefore 'from bench to bed¿.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 252 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book summarizes the research of more than a decade. Its early motivation dates back to the eighties and to the memorable talks Dr. C. Moglestue (FHG Freiburg) gave on his Monte-Carlo solutions of the Boltzmann transport equation at the NASECODE conferences in Ireland. At that time numerical semiconductor device modeling basically implied the application of the drift-diffusion model. On the one hand, those talks clearly showed the potential of the Monte-Carlo model for an accurate description of many important transport issues that cannot adequately be addressed by the drift-diffusion approximation. On the other hand, they also clearly demonstrated that at that time only very few experts were able to extract useful results from a Monte-Carlo simulator. With this background, Monte-Carlo research activities were started in 1986 at the University of Aachen (RWTH Aachen), Germany. Different to many other Monte-Carlo research groups, the Monte-Carlo research in Aachen took place in an environment of active drift-diffusion and hydrodynamic model development.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 280 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Most organic molecules retain their integrity when dissolved, and even though in such cases the effects exerted by solvents are, in the language of the coordination chemist, of the 'outer sphere' kind, the choice of solvent can be critical to the successful outcome of an operation or preparation. Solubilities of reactants and products must be taken into account, and even if the organic principals in the reactions retain their integrity, many of the reagents are electrolytes, and their state of aggregation will affect their reactivity. In testifying to the importance of understanding solute-solvent interactions I draw attention to a large class of inorganic species for which the involvement in the chemical and physical properties by the solvent is even more deeply seated. It is comprised by the large body of metal atoms in low oxidation states for which solvent molecules intervene as reagents. At the same time, because the ions carry charges, the effects arising from outer sphere interactions are usually greater than they are for neutral molecules. To cite an example: when FeCb(s) is dissolved in water to form a dilute - say O. OlO- solution there is a complete reorganization of the coordination sphere of the cation. Whereas in the solid each cation is surrounded by six chloride ions, in the solution the dominant form is [Fe(H20)6]3+ followed by [Fe(H20)sCI]2+, [Fe(H20)4CI2]+, etc. in rapidly decreasing abundance.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 236 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Endoscopic microsurgery is a developing technique in plastic surgery. There are many advantages over traditional methods: improved access to difficult and hidden areas, better mobility, one optical instrument for endoscopic dissection and the microsurgical part, reduced overall costs, and a possibility to develop new procedures supported by the use of the endoscope.In the first volume of the series 'Update in Plastic Surgery¿ internationally acknowledged experts give an up-to-date view of the clinical possibilities in plastic surgery which result from video-assisted microsurgery with the endoscope. Advantages and disadvantages are discussed, and reasons are presented why it can be assumed that this technique will be the standard in plastic surgery within a few years.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 156 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As an addition to the European postgraduate training system for young neurosurgeons we began to publish in 1974 this series of Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association of Neurosurgical Societies. This series was first discussed in 1972 at a combined meeting of the Italian and German Neurosurgical Societies in Taormina, the founding fathers of the series being Jean Brihaye, Bernard Pertuiset, Fritz Loew and Hugo KrayenbtihI. Thus were established the principles of European co operation which have been born from the European spirit, flourished in the European Association, and have throughout been associated with this series. The fact that the English language is well on the way to becoming the international medium at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contributions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publi cation of any volume. Our series is not intended to compete with the publications of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fields and constitute the first part of each volume. 300 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As an addition to the European postgraduate training system for young neurosurgeons we began to publish in 1974 this series of Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association of Neurosurgical Societies. This series was first discussed in 1972 at a combined meeting of the Italian and German Neurosurgical Societies in Taormina, the founding fathers of the series being Jean Brihaye, Bernard Pertuiset, Fritz Loew and Hugo Krayenbiihl. Thus were established the principles of European co operation which have been born from the European spirit, flourished in the European Association, and have throughout been associated with this series. The fact that the English language is well on the way to becoming the international medium at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contributions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publi cation of any volume. Our series is not intended to compete with the publications of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fields and constitute the first part of each volume. 332 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Protists are fascinating organisms that have diversified and protozoologists. For example, phycologists use the evolutionarily to inhabit most of the biosphere. Their term 'basal body' while protozoologists use 'kine tosome'; mycologists were indifferent and used both cytoskeleton is the primary reason that such a diver sification is possible. Microtubules provided freedom terms! from the constraint of prokaryotic cell walls and they As knowledge increased, it became more and more were organized in various cytoskeletal configurations. apparent that the organisms studied in the classical The nine pairs plus two flagellum, a major component fields did not fit into monophyletic lineages. And when of many protistan cytoskeletons, gave a new meaning efforts were made to organize the protists into a phy to the word motility beginning at least one thousand logenetic classification, it became strikingly apparent million years ago. Associated with the development of that we needed a common vocabulary. Until such a the flagellum were new contractile and noncontractile common vocabulary exists, it will remain difficult to proteins that are necessary for control and manipu compare studies by scientists from different fields, it lation of the flagella. As the new protists ventured out will be difficult to identify homologous structures into new habitats and filled new niches, they evolved among protists, and the historical barriers created by new ways of sensing their surrounding environment. individual fields of mycology, phycology and proto Phototactic responses became tightly coupled with the zoology will remain. 180 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Biological sensors are usually remarkably small, sensitive and efficient. It is highly desirable to design corresponding artificial sensors for scientific, industrial and commercial purposes.This book is designed to fill an urgent need for interdisciplinary exchange between biologists studying sensors in the natural world and engineers and physical scientists developing artificial sensors. Contributions from leading scientists in this area, whether engineers or biologists, are written to be accessible to readers from these and other disciplines. The main topics cover mechanical sensors, visual sensors and vision and chemosensors. Readers will obtain a fuller understanding of the nature and performance of natural sensors as well as enhanced appreciation for the current status and the potential applicability of artificial microsensors.Friedrich G. Barth was awarded the 'Karl-Ritter-von-Frisch-Medaille' at the 2003 Annual Conference of the German Zoological Society in Halle, Germany. 420 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Based on sophisticated clinical descriptions and characteristic symptom patters occurring during the long-term course of psychiatric diseases, Leonhards classification requires that all the clinical features fit for a diagnosis to be made. Always using his own life-long case studies, Leonhard divided the endogenous psychoses into five main nosological groups: on the one hand, the prognostically favourable unipolar affective psychoses, bipolar affective psychoses and cycloid psychoses, and, on the other hand, the prognostically unfavourable unsystematic and systematic schizophrenia. In the meantime, the reliability and validity of this classification have been confirmed by scientific studies and early results provide guidelines for the different origins and varied therapeutic approaches for the specific disease profiles. 432 pp. Englisch.…

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Computational methodologies and modeling play an increasing role for investigating mechanisms, and for diagnosis and therapy of human diseases. This progress gave rice to computational medicine, an interdisciplinary field at the interface of computer science and medicine. The main focus of computational medicine lies in the development of data analysis methods and mathematical modeling and computational simulation techniques specifically addressing medical problems. In this book we present a number of computational medicine topics spanning several scales: from molecular to cell to organ and organism. First, state-of-the-art IT infrastructure for biomedical research is presented. Then four hierarchical scales are shown: 1) At the molecular level tools are reviewed for the analysis of genome variations, gene expression data, protein sequence data, proteomics, metabolomics, and 3D structural data; 2) At the cellular level approaches in oncology and artherosclerosis are highlighted; 3) At the organ level computational anatomy tools are described; and 4) at the organism level multi-scale modeling approach with special focus on oncology is presented. 216 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Biological sensors are usually remarkably small, sensitive and efficient. It is highly desirable to design corresponding artificial sensors for scientific, industrial and commercial purposes.This book is designed to fill an urgent need for interdisciplinary exchange between biologists studying sensors in the natural world and engineers and physical scientists developing artificial sensors. Contributions from leading scientists in this area, whether engineers or biologists, are written to be accessible to readers from these and other disciplines. The main topics cover mechanical sensors, visual sensors and vision and chemosensors. Readers will obtain a fuller understanding of the nature and performance of natural sensors as well as enhanced appreciation for the current status and the potential applicability of artificial microsensors.Friedrich G. Barth was awarded the 'Karl-Ritter-von-Frisch-Medaille¿ at the 2003 Annual Conference of the German Zoological Society in Halle, Germany.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 420 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Protists are fascinating organisms that have diversified and protozoologists. For example, phycologists use the evolutionarily to inhabit most of the biosphere. Their term 'basal body' while protozoologists use 'kine tosome'; mycologists were indifferent and used both cytoskeleton is the primary reason that such a diver sification is possible. Microtubules provided freedom terms! from the constraint of prokaryotic cell walls and they As knowledge increased, it became more and more were organized in various cytoskeletal configurations. apparent that the organisms studied in the classical The nine pairs plus two flagellum, a major component fields did not fit into monophyletic lineages. And when of many protistan cytoskeletons, gave a new meaning efforts were made to organize the protists into a phy to the word motility beginning at least one thousand logenetic classification, it became strikingly apparent million years ago. Associated with the development of that we needed a common vocabulary. Until such a the flagellum were new contractile and noncontractile common vocabulary exists, it will remain difficult to proteins that are necessary for control and manipu compare studies by scientists from different fields, it lation of the flagella. As the new protists ventured out will be difficult to identify homologous structures into new habitats and filled new niches, they evolved among protists, and the historical barriers created by new ways of sensing their surrounding environment. individual fields of mycology, phycology and proto Phototactic responses became tightly coupled with the zoology will remain.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 180 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Lignans, by convention, are a group of natural products that are formed by linking two phenylpropanoid units (C C units) by oxidative coupling. Most importantly, in 6 3 a lignan, two (C C units) are bound through the central carbon of their side chains, 6 3 0 i. e. the 8 and 8 positions (1, 2). The occurrence of C C -dimers, linked at sites other 6 3 0 than the 8-8 positions, is also known and these compounds have been termed neolignans (3, 4). As these two groups of compounds have close structural as well as biosynthetic relationships, they are often associated together and incorporated under the general term 'lignan' (5). The diverse structural categorization of true lignans and of a few neolignans is presented in Fig. 1. Through the years, several review articles or books covering different facets of lignans, including their ch- istry (6, 7), biogenesis (8), synthesis (9), and biological activities (10) have been published. Enduring research for the investigation of secondary metabolites of plants has evidenced some compounds that are biogenetically related to true lignans or neolignans but bear some features not discerned in conventional lignans. These compounds or groups of compounds have been termed as 'non-conventional lignans', and include coumarinolignans, avonolignans, and stilbenolignans. The non-conventional lignans, like the conventional ones, have two C C units linked 6 3 together but have additional structural features to place them also under the category of coumarins, avonoids, or stilbenes. 280 pp. Englisch.…

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Computational methodologies and modeling play a growing role for investigating mechanisms, and for the diagnosis and therapy of human diseases. This progress gave rise to computational medicine, an interdisciplinary field at the interface of computer science and medicine. The main focus of computational medicine lies in the development of data analysis methods and mathematical modeling as well as computational simulation techniques specifically addressing medical problems. In this book, we present a number of computational medicine topics at several scales: from molecules to cells, organs, and organisms. At the molecular level, tools for the analysis of genome variations as well as cloud computing resources for medical genetics are reviewed. Then, an analysis of gene expression data and the application to the characterization of microbial communities are highlighted. At the protein level, two types of analyses for mass spectrometry data are reviewed: labeled quantitative proteomics and lipidomics, followed by protein sequence analysis and a 3D structure and drug design chapter. Finally, three chapters on clinical applications focus on the integration of biomolecular and clinical data for cancer research, biomarker discovery, and network-based methods for computational diagnostics.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 216 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -I. Die Statistik in der Gegenwart. Die Statistik gehört zu den Wesensmerkmalen moderner Kultur. Wie das naturwissenschaftliche Weltbild bemüht ist, immer mehr qualitative Unterschiede in quantitative aufzu lösen, so suchen Wissenschaft und Politik im staatlichen, gesellschaftlichen und wirtschaftlichen Bereich den festen Boden der Zahl. In stolzer Würdigung der großen Bedeutung der Statistik für die Staatspolitik trägt das Gebäude des I talienischen Statistischen Zentral instituts die Inschrift: 'Numerus fundamentum rei publicae!' Wer planmäßig Massen lenken will, muß zuvor deren Größe und Zusammensetzung kennen! Ob es sich um die quantitative oder qualitative Beeinflussung des eigenen Volkes, um die Lenkung seiner Wirtschaft oder um die Förderung seines kulturel1en Lebens handelt, immer steht am Anfang des Weges in die Zukunft die Frage: Wie liegen die Dinge in der Gegenwart M ass e, Z ah I und Zu s t a n sind d für eine vorläufige Orientierung die drei Elemente der Statistik, welche die Gren zen des Begriffes, damit aber zugleich die Leistungsgrenzen dieser allgemeinen Meßkunst bestimmen. Es gibt nicht nur Lobsprüche auf die Statistik, wie die oben angeführte In schrift! So mancher Vorwurf wurde gegen sie erhoben und noch größer ist die Zahl derjenigen, die sie nicht beachten. Es mag wohl in der Natur ihrer Zahlensprache und ihres starren Tabellengewandes liegen, daß sich die Statistik nicht all gemeinen Interesses und allgemeiner Beliebtheit erfreut und daß es oft einer mühsamen Überwindung dieser Zahlenscheu bedarf, um hinter den Zahlen das pulsierende Leben mit all seinem Reiz des Wechsels und der Gleichförmigkeit zu finden. 296 pp. Deutsch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Das vorliegende Buch ist in erster Linie vorgesehen als Lehrbuch der Kristall kunde und Mineralogie beim Unterricht für die Studierenden der Mineralogie und Petrographie sowie für solche Studierenden der Chemie und Physik, die Mineralogie als Nebenfach lernen oder sich sonst für die Probleme des kristallinen Zustandes interessieren. Zugleich dürfte es nützlich sein für Fachleute sowie Vertreter der Nachbarwissenschaften, denen Einblicke in die moderne Kristall forschung. wünschenswert sind. Mit ihrem Ziel der Erforschung des kristallinen Zustandes gehört die Kristall kunde in die Chemie und Physik, aus praktischen Gründen ist sie jedoch der Mineralogie, der Erforschung der in der Natur vorkommenden und durch die natürlichen Vorgänge entstandenen Kristallarten einverleibt worden, und die Lehrbücher der Chemie und Physik behandeln die Kristalle meistens nur flüchtig. Ein Chemiker oder Physiker ist nicht so sehr interessiert an den Mineralen, den Kristallen als Naturprodukten, als an dem kristallinen Zustand selbst, und es ist für ihn belanglos, ob die Kristallarten Minerale oder Kunstprodukte sind. In diesem Buche werden bei der Behandlung der kristallgeometrischen, -physi kalischen und -chemischen Erscheinungen viele nichtmineralische Kristallarten als Beispiele erläutert. Ebenfalls werden auch Kunstprodukte angeführt im fünften Abschnitt, welcher der speziellen Mineralogie der üblichen Lehrbücher entspricht; doch stehen aus praktischen Gründen hier die Minerale im Vorder grunde. Aus diesen Hinweisen dürfte der Sondercharakter des Buches schon einigermaßen hervorgehen. 408 pp. Deutsch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Monopyrrolic Natural Compounds Including Tetramic Acid Derivatives (Albert Gossauer) Introduction / Pyrroles from Vertebrates / Pyrroles from Invertebrates / Pyrroles from Plants / Pyrroles from Fungi / Pyrroles from Bacteria / References 236 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The volumes of this classic series, now referred to simply as 'Zechmeister' after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline. 276 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Glycosmis is a clearly defined genus within the tribe Clauseneae of the Aurantioideae subfamily of the family Rutaceae comprising about 40 species (1). Its range of distribution is centered in south and southeast Asia (India, Sri Lanka, Myanmar, Thailand, Malaysia, Indonesia) and extends to south China and Taiwan as well as to New Guinea and north Australia. Exceptions are only cultivated species like the Chinese G. parvijiora (Sims) Little, formerly called G. citrifolia (Willd. ) Lindley, which became naturalized in tropical America and Africa (Angola) (1). The shrubs or small trees are unarmed and possess pinnate or simple leaves with translucent punctate glands emitting an aromatic odor when crushed. The axillary inflorescences are usually dispersed closed panicles with small white flowers. The fruits are mostly pink, reddish or white berries of about I cm in diameter with only one or two seeds. The genus name Glycosmis originates from the sweet smell of the flowers and the sweet taste of the fleshy pericarp of the fruits. A good field and herbarium character of the genus is that the buds of new leaves are usually covered with short rusty-red hairs. In spite of the good delimitation of Glycosmis from the other closely related Clauseneae genera Clausena, Micromelum, Murraya, and Merrillia and the already existing subrevisionary treatment by Stone (1), there are still many unresolved taxonomic problems at the species level. 268 pp. Englisch.…