springer us sep 1993 (34 resultados)

Buch. Condición: Neu. Neuware - A Guide to VHDL, Second Edition is intended for the working engineer who needs to develop, document, simulate, and synthesize a design using the VHDL language. It is for system and chip designers who are working with VHDL CAD tools, and who have some experience programming in Fortran, Pascal, or C and have used a logic simulator. A Guide to VHDL, Second Edition includes a number of paper exercises and computer lab experiments. If a compiler/simulator is available to the reader, then the lab exercises included in the chapters can be run to reinforce the learning experience. For practical purposes, this book keeps simulator-specific text to a minimum, but does use the Synopsys VHDL Simulator command language in a few cases. A Guide to VHDL, Second Edition is designed as a primer and its contents are appropriate for an introductory course in VHDL. The VHDL language was updated in 1992 with some minor improvements. In most cases, the language is upward compatible. Although this book is based primarily on the VHDL 1987 standard, this new second edition indicates the significant changes in the 1992 language to assist the designer in writing upwardly compatible code.

Buch. Condición: Neu. Neuware -BiCMOS Technology and Applications, Second Edition provides a synthesis of available knowledge about the combination of bipolar and MOS transistors in a common integrated circuit - BiCMOS. In this new edition all chapters have been updated and completely new chapters on emerging topics have been added. In addition, BiCMOS Technology and Applications, Second Edition provides the reader with a knowledge of either CMOS or Bipolar technology/design a reference with which they can make educated decisions regarding the viability of BiCMOS in their own application.BiCMOS Technology and Applications, Second Edition is vital reading for practicing integrated circuit engineers as well as technical managers trying to evaluate business issues related to BiCMOS. As a textbook, this book is also appropriate at the graduate level for a special topics course in BiCMOS. A general knowledge in device physics, processing and circuit design is assumed. Given the division of the book, it lends itself well to a two-part course; one on technology and one on design. This will provide advanced students with a good understanding of tradeoffs between bipolar and MOS devices and circuits.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 422 pp. Englisch.

Buch. Condición: Neu. Neuware -Many mites possess extremely intricate life styles in close association with plant and animal hosts. Their polymorphism has made classification a challenge, and their ability to reproduce both sexually and asexually has made efforts to control their populations difficult. This, however, has given rise to theories to explain the origin and function of sexual reproduction in general. In numbers of species and geographic distribution, mites may even surpass the insects. In soils, they are a major component in the system for cycling nutrients. Unlike insects, they have invaded the marine environment. These and a number of other topics are explored in Mites. Because of their extremely small size, mites have been ignored during the development of major evolutionary and ecological theories. Yet mites routinely violate fundamental concepts such as heterochrony, sexual selection, the evolution of sex ratio, and ontogeny. Recent research methodologies have made it practical for the first time to perform experimental work with mites, and since they offer short generation times and rapid research results, they are excellent model systems. Mites announces these results and should appeal to professionals in entomology, acarology, ecology, population genetics, and evolutionary biology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 384 pp. Englisch.

Buch. Condición: Neu. Neuware -In May 1986, the Association for Behavior Analysis (ABA) established a task force on the right to effective behavioral treatment. The mandate of this task force was to identify and delineate specific rights as they apply to behavioral treatment. Impetus for this project came in part from the controversy over the use of aversive procedures, which some held had no place in treatment and, with evolution of the treatment process, were no longer necessary. In con trast, others cited evidence that programs based on positive reinforcement alone were sometimes not effective in treating severe problems. These re searchers and practitioners desired to ensure that clients and guardians be permitted to choose treatments that included punishment procedures when assessments warranted their use. The first editor approached Ogden Lindsley, president of ABA, about establishing a task force to examine this isuse. The ABA council decided to broaden the mandate to include an examination of clients' right to effective behavioral treatment in general. The first editor was asked to chair the task force and appointed Saul Axelrod, Jon S. Bailey, Judith E. Favell, Richard M. Foxx, and 0. Ivar Lovaas as members. Brian A. Iwata was appointed liaison by the ABA council.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 412 pp. Englisch.

Buch. Condición: Neu. Neuware -The current volume focuses on behavioral similarities and differences within individual animals, larger populations, and species as a whole. Research from ecological, social ontogenetic, physiological, and other perspectives is presented to explicate specific behaviors, as well as to provide a more profound understanding of how behavior work influences thought about evolutionary processes.

Buch. Condición: Neu. Neuware -The first international symposium on the subject 'The Physics and Chemistry of Si02 and the Si-Si02 Interface,' organized in association with the Electrochemical Society, Inc. , was held in Atlanta, Georgia on May 15- 20, 1988. This symposium contained sixty papers and was so successful that the sponsoring divisions decided to schedule it on a regular basis every four years. Thus, the second symposium on 'The Physics and Chemistry of Si02 and the Si02 Interface was held May 18-21, 1992 in St. Louis, Missouri, again sponsored by the Electronics and Dielectrics Science and Technology Divisions of The Electrochemical Society. This volume contains manuscripts of most of the fifty nine papers presented at the 1992 symposium, and is divided into eight chapters - approximating the organization of the symposium. Each chapter is preceded with an introduction by the session organizers. It is appropriate to provide a general assessment of the current status and understanding of the physics and chemistry of Si02 and the Si02 interface before proceeding with a brief overview of the individual chapters. Semiconductor devices have continued to scale down in both horizontal and vertical dimensions. This has resulted in thinner gate and field oxides as well as much closer spacing of individual device features. As a result, surface condition, native oxide composition, and cleaning and impurity effects now provide a much more significant contribution to the properties of oxides and their interfaces.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 524 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -Molecular approaches have opened new windows on a host of ecological and evolutionary disciplines, ranging from population genetics and behavioral ecology to conservation biology and systematics.Molecular Markers, Natural History and Evolution summarizes the multi-faceted discoveries about organisms in nature that have stemmed from analyses of genetic markers provided by polymorphic proteins and DNAs. The first part of the book introduces rationales for the use of molecular markers, provides a history of molecular phylogenetics, and describes a wide variety of laboratory methods and interpretative tools in the field. The second and major portion of the book provides a cornucopia of biological applications for molecular markers, organized along a scale from micro-evolutionary topics (such as forensics, parentage, kinship, population structure, and intra-specific phylogeny) to macro-evolutionary themes (including species relationships and the deeper phylogenetic structure in the tree of life). Unlike most prior books in molecular evolution, the focus is on organismal natural history and evolution, with the macromolecules being the means rather than the ends of scientific inquiry. Written as an intellectual stimulus for the advanced undergraduate, graduate student, or the practicing biologist desiring a wellspring of research ideas at the interface of molecular and organismal biology, this book presents material in a manner that is both technically straightforward, yet rich with concepts and with empirical examples from the world of nature.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 528 pp. Englisch.

Buch. Condición: Neu. Neuware - In response to the increasing interest in developing photonic switching fabrics, this book gives an overview of the many technologies from a systems designer's perspective. Optically transparent devices, optical logic devices, and optical hardware are all discussed in detail and set into a systems context. Comprehensive, up-to-date, and profusely illustrated, the work will provide a foundation for the field, especially as broadband services are more fully developed.

Buch. Condición: Neu. Neuware - In this volume of Methods in Pharmacology we have brought together experts in the field of ion channels to provide the reader with an in-depth view of current biochemical and electrophysiological methods. The focus is on cation-selective ion channels (voltage controlled Of ligand controlled) that are of special pharmacological interest. The con tents are divided into three sections that exemplify {I) molecular and biochemical characterization of ion channels, (II) functional analysis of ion channels (after recon stitution or expression, or in cells), and (III) specific methods and tools. The editors thank the contributors for their cooperation in assembling this volume. We are convinced that the reader will enjoy the chapters, written by leading scientists in their respective disciplines, as much as we did. Hartmut Glossmann Jarg Striessnig Innsbruck, Austria vii Contents I MOLECULAR AND BIOCHEMICAL CHARACTERIZA nON OF ION CHANNELS 1 Purification and Pharmacological Analysis of the Omega-Conotoxin 3 GVIA Receptor from Rat Brain Maureen W McEnery 2 Molecular Characterization of the Charybdotoxin-Sensitive, 41 High-Conductance, Calcium-Activated Potassium Channel Margarita Garda-Calvo, Gregory J. Kaczorowski, and Maria L. Garda 3 Characterization of the Sulfonylurea-Sensitive ATP-Modulated 61 Potassium Channel Henri Bernardi and Michel Lazdunski II FUNCTIONAL ANALYSIS OF ION CHANNELS 4 Xenopus Oocytes as an Expression System for Ion Channels 79 Alan L. Goldin ix x Contents 5 Reconstitution of Muscle Calcium Channel Function in Bilayer 99 Membranes: From the First Steps to Results Dieter J. Pelzer, Terence F.

Buch. Condición: Neu. Neuware - The hybridoma technique for producing monoclonal antibodies developed by Drs. Kohler and Millstein in 1975 revolutionized the field of tumor immunology. It is now clear that there are antigens associated with or restricted to human neoplasms that have biologic significance. Monoclonal antibodies have already been demonstrated to have great immunodiagnostic value, and it is anticipated that they will become a component of our therapeutic armamentarium. Most investigators in the field, however, feel the true potential of monoclonal antibodies in cancer therapy remains to be determined. Clearly the most encouraging results have been witnessed in the treatment of hematologic malignancies. This volume of Cancer Treatment and Research explores the current state of the art of immunoconjugate therapy of hematologic malignancies. The first chapter, authored by Drs. Rosen and Kuzel, reviews the current status of radioimmunotherapy of lymphoma. Results of clinical investigations utilizing radiolabeled immunoconjugates in B-cell lymphomas, T-cell lym phomas, and Hodgkin's disease are discussed. In addition, obstacles to effective antibody therapy are highlighted and toxicities are summarized. Chapter 2, written by Drs. Sgouros and Scheinberg, critiques the treat ment of leukemia with radiolabeled monoclonal antibodies. In this chapter, the unique features of leukemia that make it particularly suitable for radio immunotherapy are discussed, an overview of selected clinical trials is presented, and a treatment planning approach to radioimmunotherapy in corporating biologic and physical parameters is reviewed.

Buch. Condición: Neu. Neuware - This book is a compilation of the research which was presented during the NATO-Advanced Research Workshop (ARW) entitled 'Advances in Bacterial Paracrystalline Surface Layers' held in London, Ontario, Canada during September 27 to 30, 1992. The organizing committee consisted of the two Workshop directors, S. F. Kaval and T. J. Beveridge, and H. König, U. B. Sleytr and T. J. Trust; their summary statements about the significance and success of the NATO-ARWare in Chapter 37 of this book. This was the third international workshop on bacterial S-layers and it demonstrated unequivocally how rapidly research is progressing. The Workshop was made possible by financial support from the North Atlantic Treaty Organization (NATO), the Medical Research Council of Canada (MRC), the Natural Seiences and Engineering Research Council of Canada (NSERC), and the Canadian Bacterial Diseases Network (CBDN) which is a Canadian National Centre of Excellence (NCE). We are very grateful for the support from all of these agencies since their financial aid made it possible to bring to London, Canada a truly international group of S-layer experts. We encouraged the attendance and participation of graduate fellows and research associates, and their presentations students, postdoctoral was an intense three constitute the 'Poster' section of this book. The NATO-ARW day workshop held at a delightful secluded location (Spencer Hall) so that the delegates had both formal and informal occasions to interact and evolve new ideas.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Following the publication of the Handbook of the Brief Psychotherapies (Wells & Giannetti, 1990), the editors began to conceptualize the idea of a collection of case studies encompassing a number of the commonly en countered clinical problems that have been treated with such ap proaches. The Casebook of the Brief Psychotherapies is the result. The Case book details clinical interventions with client populations as diverse as substance abusers, torture victims, the physically handicapped and other exceptional groups, and the economically disadvantaged with emotional and behavioral problems, as well as individuals experiencing sexual dysfunction or eating disorders. In addition, topics such as be reavement, depression, anger, and many crucial aspects of marital and family therapy are discussed by eminent clinical practitioners. Although the cases draw heavily upon cognitive behavioral and strategic structural formulations, psychodynamic, interpersonal, and experiential ap proaches are also included. The Casebook is clinically oriented, with a minimum of theory. Am ple case material and commentary allow the reader to experience direct ly the application of brief therapy to specific client problems. What emerges from this compendium of approaches and problems is a tap estry of action-oriented, problem-solving, skill-building, rational ap proaches to therapy that balance the client's ability to change with the demands and limits of time. 416 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Corrected printingSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 232 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Following the publication of the Handbook of the Brief Psychotherapies (Wells & Giannetti, 1990), the editors began to conceptualize the idea of a collection of case studies encompassing a number of the commonly en countered clinical problems that have been treated with such ap proaches. The Casebook of the Brief Psychotherapies is the result. The Case book details clinical interventions with client populations as diverse as substance abusers, torture victims, the physically handicapped and other exceptional groups, and the economically disadvantaged with emotional and behavioral problems, as well as individuals experiencing sexual dysfunction or eating disorders. In addition, topics such as be reavement, depression, anger, and many crucial aspects of marital and family therapy are discussed by eminent clinical practitioners. Although the cases draw heavily upon cognitive behavioral and strategic structural formulations, psychodynamic, interpersonal, and experiential ap proaches are also included. The Casebook is clinically oriented, with a minimum of theory. Am ple case material and commentary allow the reader to experience direct ly the application of brief therapy to specific client problems. What emerges from this compendium of approaches and problems is a tap estry of action-oriented, problem-solving, skill-building, rational ap proaches to therapy that balance the client's ability to change with the demands and limits of time. 416 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -When we see a jumbo jet at the airport, we sometimes wonder how such a huge, heavy plane can fly high in the sky. To the extent that we think in a static way, it is certainly not understandable. In such a manner, dynamics yields behavior quite different from statics. When we want to prepare an iron nitride, for example, one of the most orthodox ways is to put iron in a nitrogen atmosphere under pressures higher than the dissociation pressure of the iron nitride at temperatures sufficiently high to let the nitrogen penetrate into the bulk iron. This is the way thermodynamics tells us to proceed, which requires an elaborate, expensive high-pressure apparatus, sophisticated techniques, and great efforts. However, if we flow ammonia over the iron, even under low pressures, we can easily prepare the nitride-provided the hydrogen pressure is sufficiently low. Since the nitrogen desorption rate is the determining step of the ammonia decomposition on the iron surface, the virtual pressure of nitrogen at the surface can reach an extremely high level (as is generally accepted) because, in such a dynamic system, the driving force of the ammonia decomposition reaction pushes the nitrogen into the bulk iron to form the nitride. Thus, dynamics is an approach considerably different from statics. 376 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Many mites possess extremely intricate life styles in close association with plant and animal hosts. Their polymorphism has made classification a challenge, and their ability to reproduce both sexually and asexually has made efforts to control their populations difficult. This, however, has given rise to theories to explain the origin and function of sexual reproduction in general. In numbers of species and geographic distribution, mites may even surpass the insects. In soils, they are a major component in the system for cycling nutrients. Unlike insects, they have invaded the marine environment. These and a number of other topics are explored in Mites. Because of their extremely small size, mites have been ignored during the development of major evolutionary and ecological theories. Yet mites routinely violate fundamental concepts such as heterochrony, sexual selection, the evolution of sex ratio, and ontogeny. Recent research methodologies have made it practical for the first time to perform experimental work with mites, and since they offer short generation times and rapid research results, they are excellent model systems. Mites announces these results and should appeal to professionals in entomology, acarology, ecology, population genetics, and evolutionary biology. 384 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -BiCMOS Technology and Applications, Second Edition provides a synthesis of available knowledge about the combination of bipolar and MOS transistors in a common integrated circuit - BiCMOS. In this new edition all chapters have been updated and completely new chapters on emerging topics have been added. In addition, BiCMOS Technology and Applications, Second Edition provides the reader with a knowledge of either CMOS or Bipolar technology/design a reference with which they can make educated decisions regarding the viability of BiCMOS in their own application. BiCMOS Technology and Applications, Second Edition is vital reading for practicing integrated circuit engineers as well as technical managers trying to evaluate business issues related to BiCMOS. As a textbook, this book is also appropriate at the graduate level for a special topics course in BiCMOS. A general knowledge in device physics, processing and circuit design is assumed. Given the division of the book, it lends itself well to a two-part course; one on technology and one on design. This will provide advanced students with a good understanding of tradeoffs between bipolar and MOS devices and circuits. 422 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As this is the first general textbook for the field published in over twenty years, the editors have taken great care to make sure coverage is comprehensive. Diagenesis of organic matter, kerogens, exploration for fossil fuels, and many other subjects are discussed in detail to provide faculty and students with a thorough introduction to organic geochemistry. 896 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In May 1986, the Association for Behavior Analysis (ABA) established a task force on the right to effective behavioral treatment. The mandate of this task force was to identify and delineate specific rights as they apply to behavioral treatment. Impetus for this project came in part from the controversy over the use of aversive procedures, which some held had no place in treatment and, with evolution of the treatment process, were no longer necessary. In con trast, others cited evidence that programs based on positive reinforcement alone were sometimes not effective in treating severe problems. These re searchers and practitioners desired to ensure that clients and guardians be permitted to choose treatments that included punishment procedures when assessments warranted their use. The first editor approached Ogden Lindsley, president of ABA, about establishing a task force to examine this isuse. The ABA council decided to broaden the mandate to include an examination of clients' right to effective behavioral treatment in general. The first editor was asked to chair the task force and appointed Saul Axelrod, Jon S. Bailey, Judith E. Favell, Richard M. Foxx, and 0. Ivar Lovaas as members. Brian A. Iwata was appointed liaison by the ABA council. 412 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The potato (Solanum tuberosum L. ) tuber is a major food source in many countries of the world, and subsequently potato has been the target of a good deal of effort directed at engineering disease and herbicide tolerance, and improvements in various crop characteristics. Consequently investigations into the regulation of gene expression in tubers is relevant to these endeavours, as tubers are the main target organ for modification of gene expression. We have been interested in the regulation of genes in tubers for these reasons. Morphologically tubers are modified stems, which have enlarged radially by limited cell division and substantial expansion. At the molecular level, tuber development is characterised by a massive increase in starch deposition and the synthesis of a limited number of abundant proteins. These include proteinase inhibitors and a 40kd group of proteins called patatin, which are acyl hydrolases. Together these proteins account for over 50% of tuber proteins (reviewed by Bevan, 1991). The synthesis of these proteins has parallels to the synthesis of other somatic storage proteins, especially the VSP proteins of soybean. In both potato and soybean, removal of the sink for these proteins (tubers and pods, respectively) causes deposition in other tissues (Staswick, 1990). It is hypothesised that transcriptional control of the genes encoding these proteins is regulated in part by source-sink relationships of metabolites or other factors. In the case of VSPs, both amino acid levels and jasmonic acid play a major regulatory role (Staswick et aI. 240 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -When we see a jumbo jet at the airport, we sometimes wonder how such a huge, heavy plane can fly high in the sky. To the extent that we think in a static way, it is certainly not understandable. In such a manner, dynamics yields behavior quite different from statics. When we want to prepare an iron nitride, for example, one of the most orthodox ways is to put iron in a nitrogen atmosphere under pressures higher than the dissociation pressure of the iron nitride at temperatures sufficiently high to let the nitrogen penetrate into the bulk iron. This is the way thermodynamics tells us to proceed, which requires an elaborate, expensive high-pressure apparatus, sophisticated techniques, and great efforts. However, if we flow ammonia over the iron, even under low pressures, we can easily prepare the nitride-provided the hydrogen pressure is sufficiently low. Since the nitrogen desorption rate is the determining step of the ammonia decomposition on the iron surface, the virtual pressure of nitrogen at the surface can reach an extremely high level (as is generally accepted) because, in such a dynamic system, the driving force of the ammonia decomposition reaction pushes the nitrogen into the bulk iron to form the nitride. Thus, dynamics is an approach considerably different from statics. 376 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book has the modest aim of bringing together methodological, theo retical, and empirical studies that bear on the phylogenetic placement of primates and their relatives, and continues a tradition started by Phylogeny of the Primates: A Multidisciplinary Approach (edited by W. P. Luckett and F. S. Szalay; Plenum Press, 1975) and The Comparative Biology and Evolutionary Rela tionships of Tree Shrews (edited by W. P. Luckett, Plenum Press, 1980). Although there are several recent compendia of studies of primate relationships, most of these are exclusively concerned with the internal arrangement of clades within the order, not with the place of primates and their relatives on the eutherian cladogram. Evolutionary theory predicts that primates must be more closely related to some non primate mammals than to others, but a continuing problem has been to find reliable procedures for recovering historical relationships among taxa. Before the 1970s, higher-level relationships among primates and euthe rian mammals that might be closely related to them were rarely treated in detail. Outstanding exceptions, like Le Gros Clark's Antecedents of Man, were just that-exceptions. (Clark himself essentially stopped with making a case for tree shrews; he did not, for example, explore whether bats and colugos were also related to primates. ) In the 1970s and 1980s, the rise of cladistic techniques and advances in molecular methods began to transform primate systematics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 400 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The potato (Solanum tuberosum L. ) tuber is a major food source in many countries of the world, and subsequently potato has been the target of a good deal of effort directed at engineering disease and herbicide tolerance, and improvements in various crop characteristics. Consequently investigations into the regulation of gene expression in tubers is relevant to these endeavours, as tubers are the main target organ for modification of gene expression. We have been interested in the regulation of genes in tubers for these reasons. Morphologically tubers are modified stems, which have enlarged radially by limited cell division and substantial expansion. At the molecular level, tuber development is characterised by a massive increase in starch deposition and the synthesis of a limited number of abundant proteins. These include proteinase inhibitors and a 40kd group of proteins called patatin, which are acyl hydrolases. Together these proteins account for over 50% of tuber proteins (reviewed by Bevan, 1991). The synthesis of these proteins has parallels to the synthesis of other somatic storage proteins, especially the VSP proteins of soybean. In both potato and soybean, removal of the sink for these proteins (tubers and pods, respectively) causes deposition in other tissues (Staswick, 1990). It is hypothesised that transcriptional control of the genes encoding these proteins is regulated in part by source-sink relationships of metabolites or other factors. In the case of VSPs, both amino acid levels and jasmonic acid play a major regulatory role (Staswick et aI.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Biological markers (biomarkers) are useful tools for understanding the nature and extent of human exposure and risk from environmental toxicants. Biomarkers are classified into three basic categories: exposure, effect, or susceptibility. A marker of exposure is the product of the interaction between a target cell or molecule and a foreign substance (NAS, 1989). These markers can be used to determine the biologically effective dose necessary to elicit a particular physiological change in an organism. A marker of effect is a biochemical or physiological change in an organism that can predict the onset of adverse health effects resulting from a given exposure. Lastly, markers of susceptibility act as indicators of an inherent or acquired tendency of an organism to experience an adverse health effect (NAS, 1989). These markers are already used to detect a variety of diseases and show great promise for developing a better understanding of the mechanicisms of disease. Additionally, biomarkers can be used to establish a more rational basis for quantitative risk extrapolation between species, as weIl as to obtain more precise estimates of the time of critical exposure. These markers can also prove helpful in identifying potentially damaging exposures before the onset of adverse health effects. Biomarkers serve as a valuable exposure assessment tool because they take into account exposure from all routes and integrate exposure from all sources. They have the potential to yield better risk estimates than current monitoring and modeling protocols. In lune 1992, Dr. Travis and Dr.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 300 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -As this is the first general textbook for the field published in over twenty years, the editors have taken great care to make sure coverage is comprehensive. Diagenesis of organic matter, kerogens, exploration for fossil fuels, and many other subjects are discussed in detail to provide faculty and students with a thorough introduction to organic geochemistry.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 896 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The current volume focuses on behavioral similarities and differences within individual animals, larger populations, and species as a whole. Research from ecological, social ontogenetic, physiological, and other perspectives is presented to explicate specific behaviors, as well as to provide a more profound understanding of how behavior work influences thought about evolutionary processes. 308 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The current volume focuses on behavioral similarities and differences within individual animals, larger populations, and species as a whole. Research from ecological, social ontogenetic, physiological, and other perspectives is presented to explicate specific behaviors, as well as to provide a more profound understanding of how behavior work influences thought about evolutionary processes. 308 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The first international symposium on the subject 'The Physics and Chemistry of Si02 and the Si-Si02 Interface,' organized in association with the Electrochemical Society, Inc. , was held in Atlanta, Georgia on May 15- 20, 1988. This symposium contained sixty papers and was so successful that the sponsoring divisions decided to schedule it on a regular basis every four years. Thus, the second symposium on 'The Physics and Chemistry of Si02 and the Si02 Interface was held May 18-21, 1992 in St. Louis, Missouri, again sponsored by the Electronics and Dielectrics Science and Technology Divisions of The Electrochemical Society. This volume contains manuscripts of most of the fifty nine papers presented at the 1992 symposium, and is divided into eight chapters - approximating the organization of the symposium. Each chapter is preceded with an introduction by the session organizers. It is appropriate to provide a general assessment of the current status and understanding of the physics and chemistry of Si02 and the Si02 interface before proceeding with a brief overview of the individual chapters. Semiconductor devices have continued to scale down in both horizontal and vertical dimensions. This has resulted in thinner gate and field oxides as well as much closer spacing of individual device features. As a result, surface condition, native oxide composition, and cleaning and impurity effects now provide a much more significant contribution to the properties of oxides and their interfaces. 524 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Molecular approaches have opened new windows on a host of ecological and evolutionary disciplines, ranging from population genetics and behavioral ecology to conservation biology and systematics. Molecular Markers, Natural History and Evolution summarizes the multi-faceted discoveries about organisms in nature that have stemmed from analyses of genetic markers provided by polymorphic proteins and DNAs. The first part of the book introduces rationales for the use of molecular markers, provides a history of molecular phylogenetics, and describes a wide variety of laboratory methods and interpretative tools in the field. The second and major portion of the book provides a cornucopia of biological applications for molecular markers, organized along a scale from micro-evolutionary topics (such as forensics, parentage, kinship, population structure, and intra-specific phylogeny) to macro-evolutionary themes (including species relationships and the deeper phylogenetic structure in the tree of life). Unlike most prior books in molecular evolution, the focus is on organismal natural history and evolution, with the macromolecules being the means rather than the ends of scientific inquiry. Written as an intellectual stimulus for the advanced undergraduate, graduate student, or the practicing biologist desiring a wellspring of research ideas at the interface of molecular and organismal biology, this book presents material in a manner that is both technically straightforward, yet rich with concepts and with empirical examples from the world of nature. 528 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Biological markers (biomarkers) are useful tools for understanding the nature and extent of human exposure and risk from environmental toxicants. Biomarkers are classified into three basic categories: exposure, effect, or susceptibility. A marker of exposure is the product of the interaction between a target cell or molecule and a foreign substance (NAS, 1989). These markers can be used to determine the biologically effective dose necessary to elicit a particular physiological change in an organism. A marker of effect is a biochemical or physiological change in an organism that can predict the onset of adverse health effects resulting from a given exposure. Lastly, markers of susceptibility act as indicators of an inherent or acquired tendency of an organism to experience an adverse health effect (NAS, 1989). These markers are already used to detect a variety of diseases and show great promise for developing a better understanding of the mechanicisms of disease. Additionally, biomarkers can be used to establish a more rational basis for quantitative risk extrapolation between species, as weIl as to obtain more precise estimates of the time of critical exposure. These markers can also prove helpful in identifying potentially damaging exposures before the onset of adverse health effects. Biomarkers serve as a valuable exposure assessment tool because they take into account exposure from all routes and integrate exposure from all sources. They have the potential to yield better risk estimates than current monitoring and modeling protocols. In lune 1992, Dr. Travis and Dr. 300 pp. Englisch.