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  • Ton De De Jong

    Idioma: Inglés

    Publicado por Springer US, Springer New York Mai 2009, 2009

    ISBN 10: 0387895116 ISBN 13: 9780387895116

    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania

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    Taschenbuch. Condición: Neu. Neuware -This volume presents a short review study of the potential relationships between cognitive neuroscience and educational science. Conducted by order of the Dutch Programme Council for Educational Research of the Netherlands Organization for Scienti c Research (NWO; cf. the American NSF), the review aims to identify: (1) how educational principles, mechanisms, and theories could be extended or re ned based on ndings from cognitive neuroscience, and (2) which neuroscience prin- ples, mechanisms, or theories may have implications for educational research and could lead to new interdisciplinary research ventures. The contents should be seen as the outcome of the ¿Explorations in Learning and the Brain¿ project. In this project, we started with a ¿quick scan¿ of the lite- ture that formed the input for an expert workshop that was held in Amsterdam on March 10¿11,2008. This expert workshopidenti ed additional relevant themesand issues that helped us to update the ¿quick scan¿ into this nal document. In this way the input from the participants of the expert workshop (listed in Appendix A) has greatly in uenced the present text. We are therefore grateful to the participants for their scholarly and enthusiastic contributions. The content of the current volume, however, is the full responsibility of the authors.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 92 pp. Englisch.

  • Jeffrey Conklin

    Idioma: Inglés

    Publicado por Springer US, Springer US Mai 2009, 2009

    ISBN 10: 0387882928 ISBN 13: 9780387882925

    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania

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    EUR 149,79

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    Buch. Condición: Neu. Neuware -While reflux disease, achalasia, esophageal spasm, gastroparesis and IBS include some of the most common disorders in all disease categories, the understanding of their pathophysiology has remained elusive. The field of clinical gastrointestinal motility has for decades relied on the measurement of intestinal movements for diagnosis and management of these difficult and enigmatic disorders of gut function. Although computers have increased the speed with which we can measure the movements of the gut, the devices to measure this movement have not changed in over 20 years. In the last 2 years, a new technologic breakthrough has taken place in the measurement of intestinal movement. The technology is called high resolution manometry. Rather than the old 4 and 8 channels systems of measuring pressure, high resolution employs 36 closely spaced solid state pressure transducers. By using this technology, the resolution of gut motor activity is incredible. This allows for better ways of viewing motility using color as pressure. This technology makes for beautiful images of gut motility that we have never seen before. We have made diagnoses that would never have been appreciated with the old technology. High resolution manometry is taking over conventional manometry worldwide and represents a dramatic leap in a long time stagnant area.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 104 pp. Englisch.

  • Yevgeni Koucheryavy

    Idioma: Inglés

    Publicado por Springer Us Mai 2009, 2009

    ISBN 10: 0387855726 ISBN 13: 9780387855721

    Librería: AHA-BUCH GmbH, Einbeck, Alemania

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    EUR 162,42

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    Buch. Condición: Neu. Neuware - The current book provides a final report of activity performed by the COST 290 Action, ''Traffic and QoS Management in Wireless Multimedia Networks,'' which ran from March 10, 2004, until June 3, 2008. After an introduction to the COST framework and the Action's survey time-frame and activities, the main part of the book addresses a number of technical issues, which are structured into several chapters. All those issues have been carefully investigated by the COST 290 community during the course of the project - the information presented in this book can be regarded as ultimate for each particular topic; every open research issue addressed in the book is described carefully, corresponding existing studies are analyzed and results achieved by the COST 290 community are presented and compared, and further research directions are defined and analyzed. Because the book covers a wide area of research addressing issues of modern wired and wireless networking at different layers, starting from the physical layer up to the application layer, it can be recommended to be used by researchers and students to obtain a comprehensive analysis on particular research topics including related areas, to obtain broad and ultimate referencing, and to be advised on current open issues. COST 290 is one of the Actions of the European COST Program. Founded in 1971, COST is an intergovernmental framework for European Cooperation in the field of Scientific and Technical Research, allowing the coordination of nationally funded research on a European level.

  • Robert Mason

    Idioma: Inglés

    Publicado por Springer US, Springer US Mai 2009, 2009

    ISBN 10: 0387939571 ISBN 13: 9780387939575

    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania

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    Buch. Condición: Neu. Neuware -Mercury, primarily because of its existence and bioaccumulation as methylmercury in aquatic organisms, is a concern for the health of higher trophic level organisms, or to their consumers. This is the major factor driving current research in mercury globally and in environmental regulation, and is the driver for the current UNEP Global Partnership for Mercury Transport and Fate Research (UNEP F&T) initiative. The overall focus of the UNEP F&T report is to assess the relative importance of different processes/mechanisms affecting the transfer of mercury (Hg) from emission sources to aquatic and terrestrial receptors and provide possible source-receptor relationships. This transfer occurs through atmospheric transport, chemical transformations and subsequent deposition, and involves the intermittent recycling between reservoirs that occurs prior to ultimate removal of Hg from the atmosphere. Understanding the sources, the global Hg transport and fate, and the impact of human activity on the biosphere, requires improved knowledge of Hg movement and transformation in the atmosphere. An improved understanding of Hg emission sources, fate and transport is important if there is to be a focused and concerted effort to set priorities and goals for Hg emission management and reduction at the national, regional and global levels; and to develop and implement such policies and strategies. To achieve this, a series of coordinated scientific endeavors focused on the estimation of sources, measurement and validation of concentrations and processes, and modeling, coupled with interpretation of the results within a policy framework, is likely to be required.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 660 pp. Englisch.

  • Libro 78 de 180: Cancer Treatment and Research

    Hau C. Kwaan

    Idioma: Inglés

    Publicado por Springer US, Springer US Mai 2009, 2009

    ISBN 10: 0387799613 ISBN 13: 9780387799612

    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania

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    Buch. Condición: Neu. Neuware -Coagulation in Cancer informs professionals working in the field of cancer about the pathophysiologic mechanisms of cancer-related thrombosis and bleeding. It provides assistance in recognizing the various bleeding and clotting disorders associated with cancer and includes current recommendations for the management of hemorrhage, and prevention and treatment of thrombosis in the patient with malignancy. This volume is a valuable addition to the literature on cancer and coagulation.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 356 pp. Englisch.

  • Wolfgang Minker

    Idioma: Inglés

    Publicado por Springer US, Springer New York Mai 2009, 2009

    ISBN 10: 0387764844 ISBN 13: 9780387764849

    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania

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    Buch. Condición: Neu. Neuware -Over the last decade a number of research areas have contributed to the concept of advanced intelligent environments, these include ubiquitous computing, pervasive computing, embedded intelligence, intelligent user interfaces, human factors, intelligent buildings, mobile communications, domestic robots, intelligent sensors, artistic and architectural design and ambient intelligence. Undeniably, multimodal spoken language dialogue interaction is a key factor in ensuring natural interaction and therefore of particular interest for advanced intelligent environments. The book covers all the key topics in the field of intelligent environments from a variety of leading researchers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 312 pp. Englisch.

  • Michael T. Arts

    Idioma: Inglés

    Publicado por Springer New York, Springer US Mai 2009, 2009

    ISBN 10: 0387886079 ISBN 13: 9780387886077

    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania

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    Buch. Condición: Neu. Neuware -Evidence now suggests that the roles of essential fatty acids as growth promoters and as indices of health and nutrition are fundamentally similar in freshwater and marine ecosystems. Lipids in Aquatic Ecosystems integrates this divergent literature into a coordinated, digestible form.Chapters are organized so as to discuss and synthesize the flow of lipids from lower to higher trophic levels, up to and including humans. Linkages between the production, distribution and pathways of these essential compounds within the various levels of the aquatic food webs, and their ultimate uptake by humans and other terrestrial organisms, are highlighted throughout the book. This book will be of interest to researchers and resource managers working with aquatic ecosystems.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 400 pp. Englisch.

  • Katsuhiko Mikoshiba

    Idioma: Inglés

    Publicado por Springer US, Springer New York Mai 2009, 2009

    ISBN 10: 0387303383 ISBN 13: 9780387303383

    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania

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    EUR 213,99

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    Buch. Condición: Neu. Neuware -This volume of the Handbook of Neurochemistry and Molecular Biology focuses on molecular events involved in synapse formation, synaptic plasticity and ongoing neural activity. The volume explores axonal growth cones, synapse development, and mechanisms of LTP and LTD, and calcium dynamics. Particular attention is given to function and trafficking of membrane proteins including various ion channels, aquaporines, gap junctions.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 648 pp. Englisch.

  • Libro 79 de 180: Cancer Treatment and Research

    Claas Ulrich

    Idioma: Inglés

    Publicado por Springer US, Springer New York Mai 2009, 2009

    ISBN 10: 0387785736 ISBN 13: 9780387785738

    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania

    Calificación del vendedor: 5 de 5 estrellas Valoración 5 estrellas, Más información sobre las valoraciones de los vendedores

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    Buch. Condición: Neu. Neuware -Organ transplantation has been performed for almost 40 years with steadily increasing success regarding long-time survival of the graft, as well as quality of life for the patient. However, graft tolerance only can be achieved via induction and maintenance of an impaired immunological surveillance. An increase of skin cancers as a consequence of the lowered cellular immunoresponse seems to parallel the overall increased long-time survival rate of organ transplant recipients. Against the background of chronic immunosuppression known risk factors like the amount of sun exposure prior and post transplantation, oncogenic viruses as well as the genetic background, and place of residence (latitude) are strongly related with the increased skin cancer incidence.The increasing incidence of non-melanoma skin cancer, paralleling a prolonged survival of patients after organ transplantation, represents a significant reason for morbidity and long-term morbidity in organ transplant recipients worldwide. The incidence of non-melanoma skin cancer in liver-, kidney- and heart transplant recipients varies from 1.5 to 22 %, 2 to 24 % and 6 to 34 % afterSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 516 pp. Englisch.

  • Pietro Alessandrini

    Idioma: Inglés

    Publicado por Springer Us Mai 2009, 2009

    ISBN 10: 0387980776 ISBN 13: 9780387980775

    Librería: AHA-BUCH GmbH, Einbeck, Alemania

    Calificación del vendedor: 5 de 5 estrellas Valoración 5 estrellas, Más información sobre las valoraciones de los vendedores

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    EUR 247,94

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    Buch. Condición: Neu. Neuware - The editors and contributors tackle a timely subject, and present rigorous research and analysis to demonstrate counter-intuitive results. In so doing, they reinforce the connections between organization and policy in the banking industry and its impact on entrepreneurship, through lending and credit to small and medium-sized businesses. The editors present a carefully organized manuscript that presents both literature reviews and the results of original empirical research that will be of interest to academics and professionals in finance, economics, and policy. The authorship and coverage are global. One of the authors, Michele Fratiani, has close ties to Springer, by virtue of his being a founding editor of Open Economies Review and co-editor of the book series, European and Transatlantic Studies.

  • Libro 27 de 42: Advances in Database Systems

    Sharma Chakravarthy

    Idioma: Inglés

    Publicado por Springer Us Mai 2009, 2009

    ISBN 10: 0387710027 ISBN 13: 9780387710020

    Librería: AHA-BUCH GmbH, Einbeck, Alemania

    Calificación del vendedor: 5 de 5 estrellas Valoración 5 estrellas, Más información sobre las valoraciones de los vendedores

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    EUR 247,94

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    Buch. Condición: Neu. Neuware - In recent years, a new class of applications has come to the forefront { p- marily due to the advancement in our ability to collect data from multitudes of devices, and process them e ciently. These include homeland security - plications, sensor/pervasive computing applications, various kinds of mo- toring applications, and even traditional applications belonging to nancial, computer network management, and telecommunication domains. These - plications need to process data continuously (and as long as data is available) from one or more sources. The sequence of data items continuously gen- ated by sources is termed a data stream. Because of the possible never-ending nature of a data stream, the amount of data to be processed is likely to be unbounded. In addition, timely detection of interesting changes or patterns or aggregations over incoming data is critical for many of these applications. Furthermore, the data arrival rates may uctuate over a period of time and may be bursty at times. For most of these applications, Quality of Service (or QoS) requirements, such as response time, memory usage, and throughput are extremely important. These application requirements make it infeasible to simply load the incoming data streams into a persistent store and process them e ectively using currently available database management techniques.

  • Mieso Denko

    Idioma: Inglés

    Publicado por Springer Us Mai 2009, 2009

    ISBN 10: 0387898271 ISBN 13: 9780387898278

    Librería: AHA-BUCH GmbH, Einbeck, Alemania

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    Buch. Condición: Neu. Neuware - Autonomic Computing and Networking presents introductory and advanced topics on autonomic computing and networking with emphasis on architectures, protocols, services, privacy & security, simulation and implementation testbeds. Autonomic computing and networking are new computing and networking paradigms that allow the creation of self-managing and self-controlling computing and networking environments using techniques such as distributed algorithms and context-awareness to dynamically control networking functions without human interventions. Autonomic networking is characterized by recovery from failures and malfunctions, agility to changing networking environment, self-optimization and self-awareness. The self-control and management features can help to overcome the growing complexity and heterogeneity of exiting communication networks and systems. The realization of fully autonomic heterogeneous networking introduces several research challenges in all aspects of computing and networking and related fields.

  • Ton De De Jong

    Idioma: Inglés

    Publicado por Springer US Mai 2009, 2009

    ISBN 10: 0387895116 ISBN 13: 9780387895116

    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania

    Calificación del vendedor: 5 de 5 estrellas Valoración 5 estrellas, Más información sobre las valoraciones de los vendedores

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents a short review study of the potential relationships between cognitive neuroscience and educational science. Conducted by order of the Dutch Programme Council for Educational Research of the Netherlands Organization for Scienti c Research (NWO; cf. the American NSF), the review aims to identify: (1) how educational principles, mechanisms, and theories could be extended or re ned based on ndings from cognitive neuroscience, and (2) which neuroscience prin- ples, mechanisms, or theories may have implications for educational research and could lead to new interdisciplinary research ventures. The contents should be seen as the outcome of the 'Explorations in Learning and the Brain' project. In this project, we started with a 'quick scan' of the lite- ture that formed the input for an expert workshop that was held in Amsterdam on March 10-11,2008. This expert workshopidenti ed additional relevant themesand issues that helped us to update the 'quick scan' into this nal document. In this way the input from the participants of the expert workshop (listed in Appendix A) has greatly in uenced the present text. We are therefore grateful to the participants for their scholarly and enthusiastic contributions. The content of the current volume, however, is the full responsibility of the authors. 92 pp. Englisch.

  • Jeffrey Conklin

    Idioma: Inglés

    Publicado por Springer US Mai 2009, 2009

    ISBN 10: 0387882928 ISBN 13: 9780387882925

    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania

    Calificación del vendedor: 5 de 5 estrellas Valoración 5 estrellas, Más información sobre las valoraciones de los vendedores

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    EUR 149,79

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    Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -While reflux disease, achalasia, esophageal spasm, gastroparesis and IBS include some of the most common disorders in all disease categories, the understanding of their pathophysiology has remained elusive. The field of clinical gastrointestinal motility has for decades relied on the measurement of intestinal movements for diagnosis and management of these difficult and enigmatic disorders of gut function. Although computers have increased the speed with which we can measure the movements of the gut, the devices to measure this movement have not changed in over 20 years. In the last 2 years, a new technologic breakthrough has taken place in the measurement of intestinal movement. The technology is called high resolution manometry. Rather than the old 4 and 8 channels systems of measuring pressure, high resolution employs 36 closely spaced solid state pressure transducers. By using this technology, the resolution of gut motor activity is incredible. This allows for better ways of viewing motility using color as pressure. This technology makes for beautiful images of gut motility that we have never seen before. We have made diagnoses that would never have been appreciated with the old technology. High resolution manometry is taking over conventional manometry worldwide and represents a dramatic leap in a long time stagnant area. 104 pp. Englisch.

  • Wolfgang Minker

    Idioma: Inglés

    Publicado por Springer US Mai 2009, 2009

    ISBN 10: 0387764844 ISBN 13: 9780387764849

    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania

    Calificación del vendedor: 5 de 5 estrellas Valoración 5 estrellas, Más información sobre las valoraciones de los vendedores

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    Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Over the last decade a number of research areas have contributed to the concept of advanced intelligent environments, these include ubiquitous computing, pervasive computing, embedded intelligence, intelligent user interfaces, human factors, intelligent buildings, mobile communications, domestic robots, intelligent sensors, artistic and architectural design and ambient intelligence. Undeniably, multimodal spoken language dialogue interaction is a key factor in ensuring natural interaction and therefore of particular interest for advanced intelligent environments. It will therefore represent one focus of the proposed book. The book will cover all key topics in the field of intelligent environments from a variety of leading researchers. It will bring together several perspectives in research and development in the area. 312 pp. Englisch.

  • Libro 78 de 180: Cancer Treatment and Research

    Hau C. Kwaan

    Idioma: Inglés

    Publicado por Springer US Mai 2009, 2009

    ISBN 10: 0387799613 ISBN 13: 9780387799612

    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania

    Calificación del vendedor: 5 de 5 estrellas Valoración 5 estrellas, Más información sobre las valoraciones de los vendedores

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    Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Coagulation in Cancer informs professionals working in the field of cancer about the pathophysiologic mechanisms of cancer-related thrombosis and bleeding. It provides assistance in recognizing the various bleeding and clotting disorders associated with cancer and includes current recommendations for the management of hemorrhage, and prevention and treatment of thrombosis in the patient with malignancy. This volume is a valuable addition to the literature on cancer and coagulation. 356 pp. Englisch.

  • Robert Mason

    Idioma: Inglés

    Publicado por Springer US Mai 2009, 2009

    ISBN 10: 0387939571 ISBN 13: 9780387939575

    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania

    Calificación del vendedor: 5 de 5 estrellas Valoración 5 estrellas, Más información sobre las valoraciones de los vendedores

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    Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Mercury, primarily because of its existence and bioaccumulation as methylmercury in aquatic organisms, is a concern for the health of higher trophic level organisms, or to their consumers. This is the major factor driving current research in mercury globally and in environmental regulation, and is the driver for the current UNEP Global Partnership for Mercury Transport and Fate Research (UNEP F&T) initiative. The overall focus of the UNEP F&T report is to assess the relative importance of different processes/mechanisms affecting the transfer of mercury (Hg) from emission sources to aquatic and terrestrial receptors and provide possible source-receptor relationships. This transfer occurs through atmospheric transport, chemical transformations and subsequent deposition, and involves the intermittent recycling between reservoirs that occurs prior to ultimate removal of Hg from the atmosphere. Understanding the sources, the global Hg transport and fate, and the impact of human activity on the biosphere, requires improved knowledge of Hg movement and transformation in the atmosphere. An improved understanding of Hg emission sources, fate and transport is important if there is to be a focused and concerted effort to set priorities and goals for Hg emission management and reduction at the national, regional and global levels; and to develop and implement such policies and strategies. To achieve this, a series of coordinated scientific endeavors focused on the estimation of sources, measurement and validation of concentrations and processes, and modeling, coupled with interpretation of the results within a policy framework, is likely to be required. 660 pp. Englisch.

  • Daoliang Li

    Idioma: Inglés

    Publicado por Springer Us Mai 2009, 2009

    ISBN 10: 1441902120 ISBN 13: 9781441902122

    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania

    Calificación del vendedor: 5 de 5 estrellas Valoración 5 estrellas, Más información sobre las valoraciones de los vendedores

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    Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The papers in this volume comprise the refereed proceedings of the Second IFIP International Conference on Computer and Computing Technologies in Agriculture (CCTA2008), in Beijing, China, 2008. The conference on the Second IFIP International Conference on Computer and Computing Technologies in Agriculture (CCTA 2008) is cooperatively sponsored and organized by the China Agricultural University (CAU), the National Engineering Research Center for Information Technology in Agriculture (NERCITA), the Chinese Society of Agricultural Engineering (CSAE) , International Federation for Information Processing (IFIP), Beijing Society for Information Technology in Agriculture, China and Beijing Research Center for Agro-products Test and Farmland Inspection, China. The related departments of China's central government bodies like: Ministry of Science and Technology, Ministry of Industry and Information Technology, Ministry of Education and the Beijing Municipal Natural Science Foundation, Beijing Academy of Agricultural and Forestry Sciences, etc. have greatly contributed and supported to this event. The conference is as good platform to bring together scientists and researchers, agronomists and information engineers, extension servers and entrepreneurs from a range of disciplines concerned with impact of Information technology for sustainable agriculture and rural development. The representatives of all the supporting organizations, a group of invited speakers, experts and researchers from more than 15 countries, such as: the Netherlands, Spain, Portugal, Mexico, Germany, Greece, Australia, Estonia, Japan, Korea, India, Iran, Nigeria, Brazil, China, etc. 4612 pp. Englisch.

  • M. Vázquez

    Idioma: Inglés

    Publicado por Springer New York, Springer US Mai 2009, 2009

    ISBN 10: 0387927891 ISBN 13: 9780387927893

    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania

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    Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The Sun is nowadays observed using di erent techniques that provide an almost instantaneous 3-D map of its structure. Of particular interest is the studyofthevariabilityinthesolaroutputproducedbythedissipationofm- netic energy on di erent spatial and temporal scales ¿ the so-called magnetic activity. The 11-year cycle is the main feature describing this phenomenon. Apart from its intrinsic scienti c interest, this topic is worth studying because of the interaction of such processes with the terrestrial environment. A eet of space and ground-based observatories are currently monitoring the behaviour of our star on a daily basis. However, solar activity varies not only on this decadal time-scale, as has been attested mainly through two methods: (a) records of the number of sunspots observed on the solar surface from 1610, and (b) the records of 14 10 cosmogenic isotopes, such as Cand Be, measured in tree-rings and i- cores, respectively. The study of the long-term behaviour of solar activity may be comp- mented by the study of historical accounts describing phenomena directly or indirectly related to solar activity. Numerous scienti c and non-scienti c d- uments have reported these events and we can make use of them as a proxy of solar activity in past times.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 400 pp. Englisch.

  • James Mohler

    Idioma: Inglés

    Publicado por Springer New York, Springer US Mai 2009, 2009

    ISBN 10: 0387691774 ISBN 13: 9780387691770

    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania

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    Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Androgens are critical regulators of prostate differentiation and function, as well as prostate cancer growth and survival. Therefore, androgen ablation is the preferred systemic treatment for disseminated prostate cancer. Androgen action is exerted in target tissues via binding the androgen receptor (AR), a nuclear receptor transcription factor.Historically, the gene expression program mediated by the AR has been poorly understood. However, recent gene expression profiling and more traditional single-gene characterization studies have revealed many androgen-regulated genes that are important mediators of androgen action in both normal and malignant prostate tissue. This book will focus on the androgen-regulated gene expression program, and examine how recently identified androgen-regulated genes are likely to contribute to the development and progression of prostate cancer. Recent studies that have attempted to unravel how these genes are deregulated in androgen depletion independent prostate cancer will be includedSpringer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 836 pp. Englisch.

  • Libro 79 de 180: Cancer Treatment and Research

    Claas Ulrich

    Idioma: Inglés

    Publicado por Springer US Mai 2009, 2009

    ISBN 10: 0387785736 ISBN 13: 9780387785738

    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania

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    Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Organ transplantation has been performed for almost 40 years with steadily increasing success regarding long-time survival of the graft, as well as quality of life for the patient. However, graft tolerance only can be achieved via induction and maintenance of an impaired immunological surveillance. An increase of skin cancers as a consequence of the lowered cellular immunoresponse seems to parallel the overall increased long-time survival rate of organ transplant recipients. Against the background of chronic immunosuppression known risk factors like the amount of sun exposure prior and post transplantation, oncogenic viruses as well as the genetic background, and place of residence (latitude) are strongly related with the increased skin cancer incidence.The increasing incidence of non-melanoma skin cancer, paralleling a prolonged survival of patients after organ transplantation, represents a significant reason for morbidity and long-term morbidity in organ transplant recipients worldwide. The incidence of non-melanoma skin cancer in liver-, kidney- and heart transplant recipients varies from 1.5 to 22 %, 2 to 24 % and 6 to 34 % after 516 pp. Englisch.

  • Katsuhiko Mikoshiba

    Idioma: Inglés

    Publicado por Springer US Mai 2009, 2009

    ISBN 10: 0387303383 ISBN 13: 9780387303383

    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania

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    Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume of the Handbook of Neurochemistry and Molecular Biology focuses on molecular events involved in synapse formation, synaptic plasticity and ongoing neural activity. The volume explores axonal growth cones, synapse development, and mechanisms of LTP and LTD, and calcium dynamics. Particular attention is given to function and trafficking of membrane proteins including various ion channels, aquaporines, gap junctions. 648 pp. Englisch.