springer us chapman and hall crc nov 2012 (80 resultados)

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Teach us to live that we may dread Unnecessary time in bed Get people up and we may save Our patients from an early grave. A most revealing paraphrase by Asher\* of a verse by Bishop Thomas Ken more than adequately summarizes the plight of the immobilized patient, who often lies dormant and de pressed for years on end. In this volume, Dr. Steinberg has offered the reader a unique opportunity to share his many years of experience in caring for the immobilized patient. His careful attempt to explore the pathophysiologic effects of immobilization on a number of organ systems, combined with a host of practical aspects with regard to patient care, is unique and refreshing. This text should command the re spect of any physician faced with the vicissitudes and frus trations of caring for the immobilized. The final chapter de tailing 'The Psychological Aspects of Immobilization,' by Hammer and Kenan, offers the reader considerable insight into the essentials and value of occupational and physical therapy. It should prove most valuable to physicians as well 'Asher, R. A. ]. Dangers of going to bed. Br. Med. J. 2:907, 1947. v vi FOREWORD as social workers, paramedical personnel, and the many physical therapists who come into daily contact with the nonambulatory patient. L. V. Avioli St. Louis Preface It may be a paradox that the importance of disability and immobilization has been enhanced by the very progress of medical science. 172 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Advanced Research Institute (A.R. 1.) on 'the efficiency of Manufacturing Systems' was held under the auspices of the NATO Special Programm~ Panel on Systems Science as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international co-operation. Advanced Research Institutes are organised for the purpose of bringing together experts in a particular field of interest to identify and make known the present state of knowledge in that area and, through informed debate, to make recommendations for directions for future research that would benefit the community at large. To this end two kinds of contribution were obtained by invitation. There were those papers which were about the current state of work in the area of manufacturing systems and its organisation; in addition three theme papers were presented to provide a stimulus to the discussion in terms of ways of thinking, both about the area and about the kind of research needed. 352 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume comprised the proceedings of a NATO Advanced Study Institute held in Geilo, Norway between 29 March and 9 April 1987. Al though the principal support for the meeting was provided by the NATO Cornrni ttee for Scientific Affairs, a number of additional sponsors also contributed. Additional funds were received from: Institutt for Energiteknikk (Norway) The Norwegian Research Council for Science and Humanities NORDITA (Denmark) VISTA (Norway) The organizing cornrni ttee would like to take this opportunity to thank all sponsors for their help in promoting an exciting and rewarding meeting. This Study Institute was the ninth of a series of meetings held in Geilo on subjects related to phase transitions and was a natural successor to the 1985 meeting on Scaling Phenomena in Disordered Systems. Many of the subjects discussed at the latter meeting were revisited in 1987, with time dependence as an added feature. Often the common theme was the concept of fractals first introduced into statistical physics some six years ago. However, by no means all disordered systems can be forced into a fractal framework, and many of the lectures reinforced this lesson. 524 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains all of the papers presented at the American Chemical Society Symposium on Reflectance Spectroscopy. The Symposium was presented under the sponsorship of the Division of Analytical Chemistry, and was held on September 11 and 12,1967, at the 154th National Meeting of the American Chemical Society, Chicago, Illinois. The papers presented herein represent a renaissance of interest in reflectance spectroscopy. The techni~ue of reflec tance spectroscopy is not, of course, a new techni~ue, however, it has only been applied to problems of a chemical interest in the last decade or so. The instrumentation for this techni~ue in the ultraviolet, visible, and near infrared regions of the spectrum has been available for many years. New and exciting research is being carried out at the present time to extend these techni~ues to the infrared and far infrared regions as well. It is a pleasure for the Editor to express his gratitude to Drs. John K. Taylor and E. C. Dunlop of the Division of Analytical Chemistry, ACS, for their cooperation in making the Symposium a reality. The assistance of Miss Julie Norris of the University of Houston for her typing and manuscript organi zation skill is greatly appreciated. And lastly, but certainly not the least, the Editor would like to acknowledge the coopera tion of all of the contributors to this volume. Certainly without their cooperation, this Symposium would not have been a success. 268 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -20 Years of the European Society for Neurochemistry The first meeting of the European Society for Neurochemistry (ESN), held in Bath, England, in September 1976,recognizedthe needat thattimeto bringtogetherbothbasic and clinical neurochemists from all European countries during a period ofconsiderable political uncertainty throughout the continent. The settingofthat meeting, an informal atmosphere of some 350 delegates in a small university city, set the tone for many of the future biennial meetings, which tended to alternate between Western and Eastern Europe. The development ofthe society since that time is excellently reviewed in Chapter 1in this volume by Herman Bachelard,afounding memberofthesocietyandhostat thatfirst meeting. Iattendedthatfirst meeting very much as ajuniorneurochemistand was enthusedby the science anddetermined to make my way in the discipline. However, my next appearance at an ESN meeting had to wait until the Budapest meeting in 1984, and since that time, I have been a regular contribu tor. I was fortunate to be elected to the council in 1985 and took over the role ofsecretary from George Lunt at the Goteborg meeting in 1988, assuming the position ofESN president in 1992. During my time as an officer for the society, volunteers for meeting organization were becoming increasingly thin on the ground as funding was becoming increasingly diffi cult to obtain and the work-load became more onerous! Planning was well under way for the 1994 Jerusalem ESN meeting by 1992, but a venue for 1996 was sought. 1272 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The risks of measuring risk.- Session I: Statistical Inference of Risks.- The proper interpretation of significance tests in risk assessment.- Remarks on sequential designs in risk assessment.- Epidemiologic studies of toxic response ¿ significance requirements.- Biological models in epidemiology: radiation carcinogenesis.- Session II: Risks of Prenatal Exposures.- Dose-response relationships for adult and prenatal exposures to methylmercury.- Risk factors for deficits in early cognitive development.- Utilization of critical periods during development to study the effects of low levels of environmental agents.- Epidemiologic studies of environmental exposures in human reproduction.- Session III: Risks of Contaminated Air and Drinking Water.- Health risks of lead as judged from autopsy material.- Use of tests of pulmonary function to measure effect of air pollutants.- Experimental evaluation of air pollutants in humans as a basis for estimating risk.- Problems and possibilities of determining the carcinogenic potency of inhalable fibrous dusts and polycyclic aromatic hydrocarbons.- Session IV: Comparative Risks of Energy Sources.- Some probabilistic aspects of safety assessment.- What is the total risk of energy systems .- Have the nuclear power risk assessors failed .- Session V: Genetic and Cancer Hazards.- Cytogenetic bases for risk inference.- Problems and solutions in the estimation of genetic risks from radiation and chemicals.- Evaluation of genetic risks.- Session VI: Extrapolation to Low Doses.- Extrapolation from long term low dose animal studies -I. Review.- Extrapolation from long term low dose animal studies -II. The ED01 study.- The shapes of the radiation dose ¿ mutation response curves in Drosophila: mechanisms and implications.- The cancer risk from low level radiation.- A simple threshold model for the classical bioassay problem.- A biological basis for the linear non-threshold dose ¿ response relationship for low-level carcinogen response.- Participants. 564 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Imagine that a young physicist would approach a granting agen cy and propose to contribute to heterogeneous catalysis by studying the heat conductivity of gases in contact with a hot filament. How would he be received now How would he have been treated sixty years ago Yet, more than sixty years ago, Irving Langmuir, through his study of heat transfer from a tungsten filament, uncovered most of the fundamental ideas which are used to-day by the scientific com munity in pure and applied heterogeneous catalysis. Through his work with what were for the first time 'clean' metal surfaces, Langmuir formulated during a period of a little over ten years un til the early thirties, the concepts of chemisorption, monolayer, adsorption sites, adsorption isotherm, sticking probability, cata lytic mechanisms by way of the interaction between chemisorbed spe cies, behavior of non-uniform surfaces and repulsion between adsor bed dipoles. It is fair to say that many of these ideas constituting the first revolution in surface chemistry have since been refined through thousands of investigations. Countless papers have been pu blished on the subject of the Langmuir adsorption isotherm, the Langmuir catalytic kinetics and the Langmuir site-exclusion adsorp tion kinetics. The refinements have been significant. ThE original concepts in their primitive or amended form are used everyday by catalytic chemists and chemical engineers allover the world in their treatment of experimental data, design of reactors or inven tion of new processes. 652 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Army Materials and Mechanics Research Center has conducted the Saga more Army Materials Research Conferences, in cooperation with the Metallurgi cal Research Laboratories of the Department of Chemical Engineering and Metallurgy of Syracuse University, since 1954. The purpose of the conferences has been to gather together scientists and engineers from academic institutions, industry, and government who are uniquely qualified to explore in depth a sub ject of importance to the Army, the Department of Defense and the scientific community. Grain size and its control is a major factor governing the behavior of materi als. Knowledge that one can obtain grain sizes in the 10 micron down to sub micron range has established the basis for a new technology. This volume, Ultrafine-Grain Ceramics, addresses itself to the broad areas of: realization of fine-grain ceramics; preparation of ultrafine particle size materials; characterization of ultrafine particles and ultrafine-grain ceramics; processing and behavior of ultra fine-grain ceramics. The technical advice provided by Dr. S. K. Dutta of the Army Materials and Mechanics Research Center during the editing of this book is acknowledged. The continued active interest and support of these conferences by Dr. E. Scala, Director, Lt. Col. Joseph B. Mason, Commanding Officer, and J. F. Sullivan, Deputy Technical Director, of the Army Materials and Mechanics Re search Center is appreciated. 420 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Theoretical and experimental work on solids with low-dimensi onal cooperative phenomena has been rather explosively expanded in the last few years, and it seems to be quite fashionable to con tribute to this field, especially to the problem of one-dimensional metals. On the whole, one could divide the huge amount of recent investigations into two parts although there is much overlap bet ween these regimes, namely investigations on magnetic exchange interactions constrained to mainly one or two dimensions and, secondly, work done on Id metallic solids or linear chain compounds with Id delocalized electrons. There is, of course, overlap from one extreme case to the other with these solids and in some rare cases both phenomena are studied on one and the same crystal. In fact, however, most of the scientific groups in this area could be associated roughly with one of these categories and,in addition, a separation between theoreticians and experimentalists in each of these groups leads to a further splitting of interests although many theories about these solids have been tested by experimenta lists. Nevertheless, more cooperation and understanding between scientists working on low-dimensional cooperative phenomena should appreciably stimulate further development. With a better inderdis ciplinary understanding, new ideas could possibly help chemists in synthesizing tailor-cut solids. This would in return give experi mentalists new phenomena to examine and finally would stimulate new theoretical work. 360 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Two infonnal meetings of consultants expert in hemostatic phenomena and in atherogenesis were held in Bethesda, Maryland, in December 1975 and February 1976 by the National Heart, Lung, and Blood Institute. Their purpose was to discuss the current status of knowledge concerning the thrombotic process in the pathogenesis of atherosclerosis. It was readily agreed that thrombosis often played a major role in plaque building and in plaque complication. It was also commented, however, that the data were qualitative in nature and that quantitative infonnation was remarkably sparse. The term thromboatherogenesis was thought to be appropriate for those phenomena in which the full expression of the thrombotic process is manifest. At the same time, recent research was noted in which what appears to be an important pathway for the initiation of atherogenesis arises from the reaction of platelets with injured arterial endothelium and'Subendothelium without necessarily involving the complete classical thrombotic process. A name was not coined for this circumstance, but it was held that thromboatherogenesis was not a fully appropriate one. 568 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The past decade has witnessed a vigorous growth in activities toward the development of a variety of biomedical devices ranging from the simple A-V shunt to the complex artificial heart. Re search and development teams have been created comprising engi neers, material scientists and clinicians and, perhaps for the first time, such groups are collaboratively bringing their respec tive talents to bear on problems associated with defects in the human organism. These collaborations have resulted in a prolifera tion of new information and a rapid and continuing redefinition of the frontiers of progress. It was to keep pace with these changes, and provide an updated view of the state of the art that this meeting was conceived. The present volume marks the publication of the proceedings of the Johnson & Johnson Symposium held in Morristown, New Jersey, on July 11 and 12, 1974. It surveys the applications of polymers to medical and surgical problems and contains discus sions on the biocompatibility of polymers, polymers as biomate rials, and the use of polymers in prosthetic devices and drug re lease systems. In addition, the Symposium offers recent perspec tives on the critical problems of the material-tissue interface, the design criteria for silicone-based systems, and the varied use of polymers in artificial hearts, kidneys, eyes and lungs. 348 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Author Mark S. Gold presents the latest medical information on nicotine and tobacco's neurobiological, physiological, and psychological effects. This timely monograph also discusses the latest diagnostic and treatment programs as well as model programs for use by practitioners which were developed by the National Cancer Institute and other eminent organizations. The author also includes a comprehensive history of tobacco use. 228 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The idea for this book developed as an outcome of a multidisciplinary sym posium entitled 'Pituitary Adenoma Update' that was held at Tufts-New En gland Medical Center in April 1977. The purpose of that symposium was to put together our current knowledge of the cause of pituitary tumors and discuss the diagnostic evaluation and management that was now appropriate, in light of the rapid advances that had taken place so recently in this area. Those of our colleagues who had presented papers at the symposium, as well as a number of others, were invited to contribute to this volume, which should serve as a presentation of the 'state of the art' on all aspects of pitu itary tumors. We felt that such a book would be of value to endocrinologists, neurosurgeons, neuroradiologists, and pathologists who are involved in the investigation or care of patients with pituitary disorders. For a number of reasons, a review of pituitary adenomas seems particu larly timely. Rapid advances have taken place coincidentally in the fields of neurosurgery, neuroendocrinology, neuroradiology, neuropathology, and neuropharmacology. Seven major developments in these areas have occurred independently and almost simultaneously that have virtually revolutionized our approach to pituitary adenomas. 536 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In July 1972, the U.S. Office of Naval Research identified several areas that it interpreted as being of interest to the U.S. Navy. Four of these research areas were then selected for their special importance in understanding physical processes on the ocean floor. In some of these, a great wealth of data has accumulated over the past two or three decades, but controversy exists in the interpretation of the results. In others, new techniques have re cently been devised that could lead to the collection and synthesis of new information. There was yet a third area in which little study had been undertaken and the results available appeared of great potential importance. The latter subject constitutes the title of this volume. To assess the information available and to facilitate plans for further research in the fields of interest that had been identified, the U.S. Office of Naval Research sponsored four symposia. The first was held in November 1972 at the University of California Con ference Center, Lake Arrowhead. The title of the symposium was 'Natural Gases in Marine Sediments and Their Mode of Distribution'. Twenty lectures were presented over a three-day period. All but two participants at this symposium subsequently submitted papers, which are published in this volume. In addition, Dr. K.O. Emery, who did not attend the symposium, supplied a manuscript on a topic most re levant to the subject matter discussed. 336 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the early 1980s capillary liquid chromatography was being established; it was a period in which only a few research groups published a relatively small number of papers on the subject. In terest has since taken off, and a period of intense development, to which no end is yet in sight, is now upon us. More investiga tors and instrument-making firms are now entering the field. This greater interest has resulted in the rapid appearance of two collec tions [1, 2] and a series of topical reviews [3-6]. However, it could hardly be said that all the problems in this area have been formulated, let alone solved. The preparation of very efficient - open tubular or packed - microbore columns, for example, remains more an art than a science, while the relation ship between radial and longitudinal mass transfer, and the effect of transcolumn velocity profiles on chromatographic efficiency, have been very poorly studied. Indeed, recent publications on these subjects have sometimes, far from clarifying matters, only muddied them further. Many instrument-making firms are trying to unify their equip ment so that it is suitable for microbore, conventional (analytical), and preparative liquid chromatography. This approach has not real ized the full potential of capillary chromatography, and there also remains room for improving the performance of capillary columns. 264 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Advanced Study Institute on 'Photoionization and Other Probes of Many-Electron Interactions' was held at the Centre 'Les Cigales' in Carry-Ie-Rouet (France), from August 31st till September 13th 1975. The Institute was sponsored by the Scienti fic Affairs Division of NATO. The 'Centre National de la Recher che Scientifique' (France) gave also partial support to the French participants and the National Science Foundation (U. S . A. ) to the American participants. A total of 18 lecturers, and 54 students selected among more than 120 applicants, attended the Institute. Over the last few years, substantial progress has been made in the experimental study of photon- or electron interactions with atoms. In particular, the g. rowing number of facilities created to use the synchrotron radiation makes now possible the realization of new types of experiments. The accumulation of new results showed clearly it was necessary to introduce electron correlations in the theoretical models in order to explain the existence and the probability of a large number of processes, in particular multiple processes. Thus large progress has also been made in the theore tical description of the excitation of the electronic systems and their interactions. It was the purpose of this Institute to bring together theoreticians and experimentalists in order to provide an opportunity to present in details the state of the art, in experiment as well as in theory, and to favor discussions on future experimen tal and theoretical studies. 492 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During October 18-30, 1981, the second course of the International School of Pure and Applied Biostructure, a NATO Advanced Study Institute, was held at the Ettore Majorana Center for Scientific Culture in Erice, Italy, co-sponsored by the International Union Against Cancer, the Italian League Against Cancer, the Italian Ministry of Public Education, the Italian Ministry of Scientific and Technological Research, the North Atlantic Treaty Organization, the Italian National Research Council, the Sicilian Regional Government and two pharmaceutical Companies (Zambeletti and Farmitalia). The subject of the course was 'Chemical Carcino genesis' with participants selected world-wide from 18 different countries. It is now eminently clear that.the bulk of human cancers are related to one of several types of environmental exposure. Of the environmental hazards, chemicals are among the best characterized carcinogens. However, how chemicals induce cancer is still poorly understood. Because of the magnitude of the problem and the ob vious need for a much more critical scientific analysis of the process by which cancer is induced (carcinogenesis), it was highly desirable to expose a greater number of scientists with varying background to some of the latest thinking in chemical carcino genesis. The course had this as its major objective and the re sulting book does reflect it. 516 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the course of the development of surface science, advances have been identified with the introduction of new diagnostic probes for analytical characterization of the adsorbates and microscopic structure of surfaces and interfaces. Among the most recently de veloped techniques, and one around which a storm of controversy has developed, is what has now been earmarked as surface enhanced Raman scattering (SERS). Within this phenomenon, molecules adsorbed onto metal surfaces under certain conditions exhibit an anomalously large interaction cross section for the Raman effect. This makes it possible to observe the detailed vibrational signature of the adsorbate in the ambient phase with an energy resolution much higher than that which is presently available in electron energy loss spectroscopy and when the surface is in contact with a much larger amount of material than that which can be tolerated in infrared absorption experiments. The ability to perform vibrational spectroscopy under these conditions would lead to a new understanding about the chemical identity, geome try, and bonding of adsorbed material at a level previously unacces sible. It is for these reasons that the last few years have brought an explosion of activity surrounding the exploitation of SERS. The search for the origines) of the anomalous enhancement has given rise to a research sub-activity of its own. Efforts to explain the en hancement have led to an increased understanding of the whole range of phenomena associated with the interaction of photons with adsor bates and metal surfaces. 436 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -''An exciting glance at key issues in contemporary hematopoiesis.'' -The Quarterly Review of Biology 260 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In 1897, Ehrlich suggested that natural preformed receptors from the surface of cells provided immunity to various chemical substances. Many years later, in 1940, Pauling proffered the concept that antibodies comprised a single poly peptide chain and that each end of the protein could form an antigen-binding site. Burnet tried to explain the diversity of antibody specificity by hypothesizing that it was cell-derived. These hypotheses probably have led to as much or more experimentation and discussion than any other of the many conjectures set forth to explain immunity on a molecular and cellular basis. Extensive investigations, initially stimulated by these propositions, proved Pauling's notion incorrect. In its demise, however, the multichain structure of the immunoglobulins was realized. In retrospect it be comes obvious that Ehrlich's idea, though not correct, was borne of amazing logic and cognition. Expansion of Burnet's theory seems to be occurring presently; much excitement is engendered by the finding of cell-bound immunoglobulin receptors. Ouring the preceding dozen years, immunochemists have accumulated enormous quantities of data. Though there is so much yet to be done, as a result of this research one may now discuss antigen-binding sites in relation to the protein's primary structure. There is even considerable understanding of the cellular assembly of some immunoglobulins. Entire books can be written about the chemistry of antigens and of complement. 200 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the last decade, the evolution of electrochemistry away from concern with the physical chemistry of solutions to its more fruitful goal in the study of the widespread consequences of the transfer of electric charges across interphases has come to fruition. The turning of technology away from an onward rush, regardless, to progress which takes into account repercussions of techno logical activity on the environment, and the consequent need for a reduction and then termination of the injection of CO into 2 the atmosphere (greenhouse effect), together with a reckoning with air and water pollution in general, ensures a long-term need for advances in a basic knowledge of electrochemical systems, an increased technological use of which seems to arise from the environmental necessities. But a mighty change in attitude needs to spread among electro chemists (indeed, among all surface chemists) concerning the terms and level in which their field is discussed. The treatment of charge transfer reactions has often been made too vaguely, in terms, it seemed, of atom transfer, with the electron-transfer step, the essence of electrochemistry, an implied accompaniment to the transfer of ions across electrical double layers. The treatment has been in terms of classical mechanics, only tenable while inadequate questions were asked concerning the behavior of the electron in the interfacial transfer. No process demands a more exclusively quantal discussion than does electron transfer. 400 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 364 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume covers the latest scientific developments in the real world applications of pollution modeling. Topics covered include: the role of atmospheric models in air pollution policy and abatement strategies; integrated regional modelling; global and long-range transport; aerosols as atmospheric contaminants; model assessment and verification; and application of new concepts in different regions of the world. 688 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the invited papers presented as a symposium of The Phytochemical Society of North America which met for its annual meeting at the Asilomar Conference Center, Pacific Grove, California on June 12-16, 1985. The topic of the symposium, 'The Shikimic Acid Pathway - Recent Advances', was especially appropriate for this, the Silver Anniversary of the Society because of the many natural products derived from that pathway. The organizers of the symposium recognized that it would not be possible to cover all groups of compounds derived from shikimic acid and therefore decided to omit any detailed discussion of flavonoid compounds and lignin. Research in these two areas has been the subject of several recent symposiums and/or published volumes. By omitting these topics, it was possible to devote more attention to other, equally interesting products derived from the shikimate pathway. Each chapter in the volume authoritat~vely speaks for itself on an important topic. However, the reader is invited to enjoy the lead chapter by Ulrich Weiss who describes his role in the research on the shikimate pathway during 1952/53. We are grateful to Dr. Weiss for this charming account of his work carried out in the laboratory of Dr. B. D. Davis during that period. Those who attended the Silver Anniversary Meeting were privileged to hear Dr. Gestur Johnson reminisce about the founding of the Society, initially called the Plant Phenolics Group of North America. At the annual banquet R. Horwitz also shared with us some recollections of Dr. 356 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The International Symposium on the Immunoglobulin A System was organized in observance of the twenty-fifth anni versary of the School of Dentistry of the University of Ala bama in Birmingham. Immunoglobulin A was chosen as the sub ject of the Symposium because of its broad scope in relation to all biologic sciences, as well as for its particular rele vance to prevention of the most common human disease--dental caries. More than 500 scientists, from 13 countries, met in Birmingham, Alabama to review critically past and current research on IgA and to outline goals for integrating future investigations of the many facets of the IgA system. It is our pleasure to express sincere appreciation to the following, whose efforts made the Symposium possible: to Dr. Sidney B. Finn, Chairman, and all members of the Twenty fifth Anniversary Planning Committee for their advice and assistance; to Dr. Charles A. McCallum, Dean of the School of Dentistry, for his enthusiastic approval and support; to Dr. Frederick W. Kraus, Symposium Chairman, for the countless hours of meticulous planning that ensured the smooth execution of the Symposium; to Ms. Tonnia C. Maddox whose unstinting dedication was indispensable to the organizational success of the meeting; to those who assisted with the transcription of manuscripts and discussions: Ms. Shirley Snow, Ms. Jan Allen, Ms. Janice Buchanan, Ms. Joy Fisher, Ms. Pam Honeycutt, Ms. Mary Huckabee, Ms. Charlotte Hughes, Mr. Stephen Miles, Ms. 572 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is based on the Proceedings of the International Conference on 'Microbial Infections: Role of Biological Response Modifiers' held in Tampa, FL, May 29-31, 1991. The major purpose of this conference was to bring together in one forum prominent investigators from around the world studying a variety of microbial pathogens, including bacteria, viruses, and fungi, and the effects of biological response modifiers (BRM) on the immune response to these microorganisms. BRM have been widely utilized in the area of antitumor resistance and include not only experimental tumor cell vaccines, but also biologically active substances such as cytokines, i. e. , interferons, tumor necrosis factor, and interleukins, as well as products from bacteria which influence host resistance mechanisms. It is the belief of the organizers of this Conference that it was very timely to discuss in detail BRMs as they impact on microbial infections per se. It is now widely accepted that immunocompromised individuals, including those exposed to immunosuppressive substances such as antimetabolites used for chemothera py of malignancies, or infectious agents, such as the human immunodeficiency virus and other viruses which depress the immune response and, in turn, affect a host so as to become highly susceptible to opportunistic microorganisms, benefit from BRM stimulation of their immune system. A wide variety of immunomodulators are now being studied in terms of treating infectious diseases, as well as malignancy and autoimmune diseases. 360 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The study of cultured human tumor cells is a most obvious approach in experimental human cancer research. For many techniques in virology, immunology, biochemistry, and biophysics, for example, large amounts of cells may be required and such quantities are usually provided only when the cultures develop into established cell lines; when this happens, thorough characterization also becomes possible. The development of cell lines, therefore, is of prime importance. Recent major advances in research with animal cell systems see m to be a prologue for present and future efforts directed toward work with human tumor cells in culture. Conceivably, the most significant results in cancer research may develop from work with such cells, and so the time seemed right to define the present state of our knowledge. This is the first book dedicated exclusively to the subject: human tumor cells in vitro. Although so me of the fundamental aspects in the cultivation of human tumor ceIls, and the extent to which they represent human cancer in vivo are still unclear, I asked a number of the leading investigators in this area of research to collect and evaluate previous and present contributions, and to offer their thoughts on the questions to which answers are not yet available. Many of the chapters are concerned with techniques of cultivation. Cultures from some types of tumors have grown weIl; in many cases they have given rise to established cell lines. 580 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The last quarter-century has been marked by the extremely rapid growth of the solid-state sciences. They include what is now the largest subfield of physics, and the materials engineering sciences have likewise flourished. And, playing an active role throughout this vast area of science and engineer ing have been very large numbers of chemists. Yet, even though the role of chemistry in the solid-state sciences has been a vital one and the solid-state sciences have, in turn, made enormous contributions to chemical thought, solid-state chemistry has not been recognized by the general body of chemists as a major subfield of chemistry. Solid-state chemistry is not even well defined as to content. Some, for example, would have it include only the quantum chemistry of solids and would reject thermodynamics and phase equilibria; this is nonsense. Solid-state chemistry has many facets, and one of the purposes of this Treatise is to help define the field. Perhaps the most general characteristic of solid-state chemistry, and one which helps differentiate it from solid-state physics, is its focus on the chemical composition and atomic configuration of real solids and on the relationship of composition and structure to the chemical and physical properties of the solid. Real solids are usually extremely complex and exhibit almost infinite variety in their compositional and structural features. 620 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The rapid expansion of research activity in all disciplines of science and technology and the concomitant growth in the number of scientific publications have caused a con siderable strain on library budgets. Even well-endowed libraries find it too expensive to collect all scientific journals. Research workers therefore often find it difficult to discover the extent and nature of work done on a particular molecule. Moreover, liter ature searches, even in a well-equipped li brary, take a great deal of time and effort. In recent years the need for a comprehensive bibliography of the spectroscopy of poly atomic organic molecules, particularly the derivatives of benzene, naphthalene, and diazine, has been keenly felt. This volume has therefore been prepared to provide easy access to information on infrared, Raman, absorption, emission, fluorescence, and phosphorescence spectroscopy, and also re lated calculations. It covers about 900 or ganic ring compounds. These compounds are arranged in alphabetic order; references are given in chronological sequence for each molecule, each characterized as to the tech nique and conditions covered. Thus, much library time may be saved and, in particular, even researchers who do not have convenient access to a really good library will be able to locate pertinent references in a matter of seconds. 7 Vibrational Analysis - C.R. Acad. Sci. 132 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The progress in protein and nucleic acid chemistry together with improvements of the previously employed tissue culture techniques have led to the solution of problems such as that of the generation of antibody diversity or of the molecular structure of T and B cell membrane receptor for antigen which had challenged the past generations of immunologists. Thanks to this progress an impressive amount of knowledge has been accumulated on certain cell types that were relatively 'mysterious' until recently. The B lymphocyte represents a typical example of such a cell. With these considerations in mind, we have started to organize a NATO summer school on 'The molecular basis of B cell differentation and function' that had the specific aim of bringing up to date a selected number of young investigators. During the course, held in Santa Margheri ta Ligure, October 1-11, 1985 it became apparent that rather than a formal school we had organized an informal series of Workshops where both the Faculty members and the participants were discussing their own data in addition to reviewing the general progress in the field. The deep commi ttment of everyone to his research subj ect and the enthusiasm had caused this very successful change in the shape of the course. At the end we asked the members of the Faculty and the participants to write a summary of their data and of their point of view on selected subj ect s. 184 pp. Englisch.