springer pg dez 2011 (7 resultados)

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Rheumatology of the Upper Limbs in Clinical Practice is a comprehensive and easy-to-use training tool for practitioners to refine their strategy for clinical investigation and differential diagnosis in regional syndromes of the shoulder, elbow, forearm, wrist and hand. It combines instructive sections, providing anatomical information and various causes of particular symptoms. Case studies recreate the clinical setting by presenting the details of the case and giving an opportunity for the reader to make a diagnosis. The text is lavishly illustrated in full color, with detailed photos of patient examinations, complemented by radiographs and full color line illustrations. The text also benefits from the use of summaries using colored boxing to identify key points in diagnosis and management.Written by two of the biggest and most respected clinicians in the discipline, this book will be essential reading for rheumatologists in practice and training. 142 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph is an attempt to compile the present state of knowledge on ocean wave analysis and prediction. The emphasis of the monograph is on the development of ocean wave analysis and predic tion procedures and their utility for real-time operations and appli cations. Most of the material in the monograph is derived from journal articles, research reports and recent conference proceedings; some of the basic material is extracted from standard text books on physical oceanography and wind waves. Ocean wave analysis and prediction is becoming an important activity in the meteorological and oceanographic services of many countries. The present status of ocean wave prediction may be compar able to the status of numerical weather prediction of the mid-sixties and early seventies when a number of weather prediction models were developed for research purposes, many of which were later put into operational use by meteorological services of several countries. The increased emphasis on sea-state analysis and prediction has created a need for a ready reference material on various ocean wave analysis and modelling techniques and their utility. The present monograph is aimed at fulfilling this need. The monograph should prove useful to the ocean wave modelling community as well as to marine forecasters, coastal engineers and offshore technologists. The monograph could also be used for a senior undergraduate (or a first year graduate) level course in ocean wave modelling and marine meteorology. 214 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Estuaries, bays and contiguous coastal seas are the world's most valuable, and yet most vulnerable marine ecosystems. Fundamental to the protection and management of these important resources is an understand- ing of the physical processes involved which affect the circulation, mixing, and transport of salt, nutrients and sediment. Residual Currents and Long-Term Transport processes appear to have direct control over freshwater inflows, contaminant loadings, dispersion and transport of sediments and nutrients, and causes of declining living resources. This volume provides a comprehensive and up-to-date summary of the research results on these processes in estuaries and bays. Contributions from ten countries include results based on theoretical formulations, analyses of field data, numerical models and case studies. 544 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In recent years, large-scale advances in technology have led to greater understanding of the world on a much tinier scale: the biomolecular level. InMicro and Nano Technologies in Bioanalysis: Methods and Protocols, expert researchers from across the globe explore the technology which makes this analysis possible, investigating the worlds of microfluidics and nanotechnologies, and examining physical science techniques for the separation, detection, manipulation, and analysis of biomolecules. This volume contains innovative protocols on the application of microfluidics andthe utilization of physical science-related technologies that will prove to be invaluable in the field of molecular biology. Chapters contain cutting edge applications of emerging nanotechnologies, including quantum dots and molecular fluorescence for the imaging and tracking of biomolecules. Composed in the highly successful Methods in Molecular Biology(TM) series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.Comprehensive and groundbreaking, Micro and Nano Technologies in Bioanalysis: Methods and Protocols is a necessary tool for cellular biologists, biochemists, microbiologists, geneticists and medical researchers alike. 668 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Over the past decades, the pathogenesis, diagnosis, treatment and prevention of cardiovascular diseases have been benefited significantly from intensive research activities. In order to provide a comprehensive 'manual' in a field that has become as broad and deep as cardiovascular medicine, this volume of 'Methods in Molecular Medicine' covers a wide spectrum of in vivo and in vitro techniques encompassing biochemical, pharmacological and molecular biology disciplines which are currently used to assess vascular disease progression. Each chapter included in this volume focuses on a specific vascular biology technique and describes various applications as well as caveats of these techniques. The protocols included here are described in detail, allowing beginners with little experience in the field of vascular biology to embark on new research projects. 372 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the early years of microarray technology, efforts were directed mainly at profiling expressed genes, while recently the microarray platform has been adapted into diverse applications directed toward the investigation of the physical genome. In Microarray Analysis of the Physical Genome: Methods and Protocols, experts in the field cover DNA microarray applications for the detection and characterization of genomic DNA-associated copy number alteration, loss of heterozygosity (LOH), cytosine methylation, protein binding sites, regulatory elements, and replication timing, with an emphasis on higher eukaryote (animal) and cancer genomes. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include a brief introduction to their respective subjects, lists of the necessary materials and reagents, step-by-step protocols, and time-saving notes on troubleshooting and avoiding known pitfalls.Authoritative and easy-to-use, Microarray Analysis of the Physical Genome: Methods and Protocols is of great value to the molecular biologist or computational biologist interested in understanding the principles of these analyses or in planning future experiments using microarrays to characterize the physical genome. 224 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Target pattern recognition in innate immunity is responsible for the immediate, usually protective, responses shown against invading microorganisms, and it is the principal feature of self and non-self recognition by virtue of the recognition of structures on the microbial pathogens, which are not found on host cells. This is an area that has been very actively researched, over approximately the past 12 years, and therefore this volume provides a timely comprehensive, and up to date, summary of the types and range of cell surface, intracellular, and secreted, host proteins involved in the recognition of microbial products, and of the protective mechanisms triggered as a result of the recognition events.The Toll-like receptors, first described in Drosophila and now well-characterised on human cells, provide an excellent demonstration of the wide range of different microbial products recognised by this family of receptors and of the signalling pathways which are triggered thus leading to induction of inflammatory cytokines and the activation of genes producing antimicrobial products. In addition, several cell surface proteins involved in target pattern recognition have been described on the surfaces of macrophages (macrophage mannose receptor and macrophage scavenger receptors), and on dendritic cells (DEC205), and to be involved with the uptake and clearance of whole microorganisms and polyanioic ligands. Pattern recognition is also utilised by intracellular receptors, with NOD-like receptors in the cytosol recognizing microbial molecules and activating the production of inflammatory cytokines or pathways that induce the production of inflammatory molecules. Secreted proteins, such as the pentraxins, which includes the acute phase reacting, C-reactive protein (CRP) and serum amyloid protein (SAP), and the collectins (mannan binding lectin, lung surfactant protein A and D) and ficolins can also readily recruit killing and clearance systems. Indeed, the serum complement system, which is one of the major defence systems in the bloodstream, is efficiently activated by CR P on its binding to the phosphocholine groups of microbial phospholipids-and the subsequent interaction of the bound CR P with C1q-to give classical pathway activation, or MBL, or ficolin, binding to arrays of mannose or N-acetyl-glucosamine residues, respectively, on the surfaces of microorganisms-to give lectin pathway activation. Also, in addition to the activation and clearance events associated with complement activation by some of the secreted pattern recognition receptors, it is accepted that all these pattern recognition receptors can generally accelerate the uptake and clearance of microbes via phagocytic cells.In view of the growing interest in the cross-talk between innate and adaptive immunity, a thorough understanding of the initial recognition and triggering events, mediated via innate immune receptors, as addressed in this volume, is clearly very useful in helping to also fully understand the mechanisms of activation and control of the adaptive immune system-and to allow a full assessment of the relative roles played by innate immunity and adaptive immunity against a particular infection in higher organisms. 202 pp. Englisch.