Springer netherlands jul 2018 (45 resultados)

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  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    940241388X / 9789402413885

    Serie: Libro 31 de 42 - The Springer Series on Demographic Methods and Population Analysis

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is a critical exposition of the data and analyses from a full decade of rigorous research into how age-related changes at the individual level, along with other factors, contribute to morbidity, disability and mortality risks at the broader population level. After summarizing the state of our knowledge in the field, individual chapters offer enlightening discussion on a range of key topics such as age trajectory analysis in select and general populations, incidence/age patterns of major chronic illnesses, and indices of cumulative deficits and their use in characterizing and understanding the detailed properties of individual aging.The book features comprehensive statistical analyses of unique longitudinal data sets including the unique resource of the Framingham Heart Study, with its more than 60 years of follow-up. Culminating in penetrating conclusions about the insights gained from the work involved, this book adds much to our understanding of the links between aging and human health. 484 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414207 / 9789402414202

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -NASA's Magnetospheric Multiscale (MMS) mission is a four-spacecraft Solar Terrestrial Probe mission to study magnetic reconnection, a fundamental plasma physical process in which energy stored in a magnetic field is converted into the kinetic energy of charged particles and heat. The driver of eruptive solar events such as flares and coronal mass ejections, magnetic reconnection is also the process by which energy is transferred from the solar wind to Earth's magnetosphere. Flying in a tetrahedral formation, the four identically instrumented MMS spacecraft measure the plasma, electric and magnetic fields, and energetic particles in the regions of geospace where magnetic reconnection is expected to occur. With interspacecraft distances varying from 400 km to 10 km and instruments capable of making extremely fast measurements (30 ms for electrons), MMS has the spatial and temporal resolution needed to resolve for the first time the microphysics of the electron diffusion region. Here, the magnetic field and the plasma become decoupled, allowing reconnection to occur. During the first of its two mission phases, MMS targets the dayside magnetopause, where the interplanetary and terrestrial magnetic fields reconnect. In the second phase, MMS increases its apogee from 12 RE to 25 RE and probes the nightside magnetosphere, where energy stored in the stretched field lines of the magnetotail is explosively released in magnetospheric substorms. Launched in March 2015 into a low-inclination elliptical orbit, MMS is now in Phase 1 of science operations.This volume, which describes the MMS mission design, observatories, instrumentation, and operations, is aimed at researchers and graduate students in magnetospheric physics and plasma physics. Researchers using the publicly available MMS data will find it particularly useful. Previously published in Space Science Reviews, Volume 199, Nos. 1-4, 2016. 756 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands, Springer Netherlands Jul 2018, 2018

    9402414673 / 9789402414677

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    EUR 74,89

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book offers an introduction to the physics of nonlinear phenomena through two complementary approaches: bifurcation theory and catastrophe theory. Readers will be gradually introduced to the language and formalisms of nonlinear sciences, which constitute the framework to describe complex systems. The difficulty with complex systems is that their evolution cannot be fully predicted because of the interdependence and interactions between their different components. Starting with simple examples and working toward an increasing level of universalization, the work explores diverse scenarios of bifurcations and elementary catastrophes which characterize the qualitative behavior of nonlinear systems. The study of temporal evolution is undertaken using the equations that characterize stationary or oscillatory solutions, while spatial analysis introduces the fascinating problem of morphogenesis. Accessible to undergraduate university students in any discipline concerned with nonlinear phenomena (physics, mathematics, chemistry, geology, economy, etc.), this work provides a wealth of information for teachers and researchers in these various fields. Chaouqi Misbah is a senior researcher at the CNRS (National Centre of Scientific Research in France). His work spans from pattern formation in nonlinear science to complex fluids and biophysics. In 2002 he received a major award from the French Academy of Science for his achievements and in 2003 Grenoble University honoured him with a gold medal. Leader of a group of around 40 scientists, he is a member of the editorial board of the French Academy of Science since 2013 and also holds numerous national and international responsibilities. 484 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414908 / 9789402414905

    Serie: Libro 37 de 46 - Vertebrate Paleobiology and Paleoanthropology

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    EUR 85,59

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book contributes to the current discussion on climate change by presenting selected studies on the ways in which past human groups responded to climatic and environmental change. In particular, the chapters show how these responses are seen in the animal remains that people left behind in their occupation sites. Many of these bones represent food remains, so the environments in which these animals lived can be identified and human use of those environments can be understood. In the case of climatic change resulting in environmental change, these animal remains can indicate that a change has occurred, in climate, environment and human adaptation, and can also indicate the specific details of those changes. 252 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands, Springer Netherlands Jul 2018, 2018

    9402414207 / 9789402414202

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    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemaniabuchversandmimpf2000

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    Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -NASA¿s Magnetospheric Multiscale (MMS) mission is a four-spacecraft Solar Terrestrial Probe mission to study magnetic reconnection, a fundamental plasma physical process in which energy stored in a magnetic field is converted into the kinetic energy of charged particles and heat. The driver of eruptive solar events such as flares and coronal mass ejections, magnetic reconnection is also the process by which energy is transferred from the solar wind to Earth¿s magnetosphere. Flying in a tetrahedral formation, the four identically instrumented MMS spacecraft measure the plasma, electric and magnetic fields, and energetic particles in the regions of geospace where magnetic reconnection is expected to occur. With interspacecraft distances varying from 400 km to 10 km and instruments capable of making extremely fast measurements (30 ms for electrons), MMS has the spatial and temporal resolution needed to resolve for the first time the microphysics of the electron diffusion region. Here,the magnetic field and the plasma become decoupled, allowing reconnection to occur. During the first of its two mission phases, MMS targets the dayside magnetopause, where the interplanetary and terrestrial magnetic fields reconnect. In the second phase, MMS increases its apogee from 12 RE to 25 RE and probes the nightside magnetosphere, where energy stored in the stretched field lines of the magnetotail is explosively released in magnetospheric substorms. Launched in March 2015 into a low-inclination elliptical orbit, MMS is now in Phase 1 of science operations.This volume, which describes the MMS mission design, observatories, instrumentation, and operations, is aimed at researchers and graduate students in magnetospheric physics and plasma physics. Researchers using the publicly available MMS data will find it particularly useful.Previously published in Space Science Reviews, Volume 199, Nos. 1-4, 2016.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 756 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    940241469X / 9789402414691

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    EUR 96,29

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides a comprehensive introduction to all aspects of enzyme engineering, from fundamental principles through to the state-of-the-art in research and industrial applications.It begins with a brief history, describing the milestones of advancement in enzyme science and technology, before going on to cover the fundamentals of enzymechemistry, the biosynthesis of enzymes and their production. Enzyme stability and the reaction kinetics during enzymatic reactions are presented to show how enzymes function during catalysis and thefactors that affect their activity. Methods to improve enzyme performance are also presented, such as cofactor regeneration and enzyme immobilization. The book emphasizes and elaborates on the performance and characteristics of enzymes at the molecular level. Finally, the book presents recent advances in enzyme engineering and some key industrial application of enzymes addressing the present needs of society.This book presents essential information not only for undergraduate and graduate students, but also for researchers in academia and industry, providing a valuable reference for the development of commercial applications of enzyme technology. 220 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414541 / 9789402414547

    Serie: Libro 17 de 27 - Globalisation, Comparative Education and Policy Research

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Globalisation and Historiography of National Leaders: Symbolic Representations in School Textbooks, the 18th book in the 24-volume book series Globalisation, Comparative Education and Policy Research, explores the interrelationship between ideology, national identity, national history and historical heroes, setting it in a global context. Based on this focus, the chapters represent hand-picked scholarly research on major discourses in the field of history textbooks and symbolic representations of national heroes, and draw upon recent studies in the areas of globalisation, history textbooks, and national leaders.A number of researchers have written on the importance of teaching national history in order to foster national identity and a sense of belonging to a certain society, state, and people among the younger generation. Some nations prefer to create national heroes out of their political leaders who are still in power, and whose lives and reputation are portrayed as being eminently spotless. Using diverse comparative education paradigms from critical theory, social semiotics, and historical-comparative research, the authors analyse the unpacking of the ideological agenda hidden behind the choice and lionization (or silencing) of the preferred national heroes. They provide an informed critique of various historical narratives depicting national leaders and national heroes.The book provides an easily accessible, practical yet scholarly source of information on international concerns in the field of globalisation, history education and policy research. Offering an essential sourcebook of ideas for researchers, history educators, practitioners and policymakers in the fields of globalisation and history education, it also provides a timely overview of current changes in politically correct history education narratives in history textbooks. 308 pp. Englisch. …

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    940241441X / 9789402414417

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    EUR 106,99

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is a collection of research articles on the subject of solar flares and flares on other cool stars, which are currently extensively studied using new ground- and space-based instruments, together with highly sophisticated numerical simulations. The collectionmemorializes the work of a pioneer in the study of solar physics,Professor Zdenek Svestka(1925 Prague - 2013 Bunschoten), a leading expert in the field of solar flares and the co-founder and Editor-in-Chief of the journal Solar Physics.The book contains many contributions to the conference 'Solar and Stellar Flares: Observations, simulations and synergies', held in Prague during 23 - 27 June 2014,organised in honor and memory of Professor Svestka.Originally published as Topical Issue ofSolar Physics, Vol. 290, Issue 12, 2015. 328 pp. Englisch. …

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414630 / 9789402414639

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    EUR 106,99

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Overall, this work identifies key points to be taken into account when drawing up guidelines that govern the use ofherbicide-tolerant (HT) crops in order to preserve the effectiveness of this innovation over time. This multidisciplinary expert report, based on an international literature review, assesses the effects of the cultivation of crops possessing HT traits. HT crops may appear to be useful complementary tools when farmers are facing certain difficult weed-management situations or in the context of a diversification of weed-control strategies. Their repeated use, however, can rapidly induce changes in the weed flora that can constitute more complex challenges in terms of weed control. Issues coming up with the development of agricultural production systems including HT crops are the objects of this expert report: what are the perceptions of these varieties by society and the reasons for their adoption by farmers Are the savings on herbicides promoted by seed companies long-lasting Can the cultivation of HT crops impact biodiversity 168 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414711 / 9789402414714

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The articles republished in this book survey and summarize recent research in helioseismology as well as studies of the interior structure, dynamics and magnetism of the solar interior that are being tested and refined using the helioseismic results.Helioseismology has in the last few decades become a highly productive technique for studying the Sun's interior from observations of the vibrations of its surface. The vibrations are manifestations of resonant modes of the Sun that are continuously excited by turbulent motions in the Sun's convection zone, and a plethora of data have been obtained from dedicated ground-based and space-based observing systems.The book will be of particular interest to researchers and graduate students in the fields of helioseismology, solar interior dynamics and the solar dynamo. It will also be of interest to researchers in solar physics, solar activity, stellar physics, astrophysical fluid dynamics and asteroseismology.Originally published in Space Science Reviews, Volume 196, Issue 1-4, December 2015 368 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414487 / 9789402414486

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book offers a ready solution for those who wish to learn more about this fascinating part of our water history and makes accessible to the wider world the traditional knowledge gained from building and maintaining qanats for more than 2,500 years. There is much more here than a summary of the nature and distribution of qanats, and a more extensive journey through the philosophy, methods, tools, and terminology of qanat design and digging than previously assembled.Where does one begin to dig to ensure that the qanat tunnel will flow with water How are practical considerations of landscape factored into the design How are water quality and discharge measured How does excavation proceed through bedrock and unconsolidated soil and how is this knowledge of geology and pedology acquired How are vertical wells and tunnels excavated to maintain proper air supply, light, and water flow How does one deal with special problems like tunnel collapse, the accumulation of gasses and vapors, and the pooling of water during construction How are tools and gauges designed, maintained, and used How have qanats been incorporated into other structures like watermills, reservoirs, ice houses, and irrigation networks And how are qanats cleaned, extended, maintained through the ages, and incorporated into modern water supplies The great contribution of this work is the story it tells of the ingenuity and practical skills of the qanat masters who for centuries and generations have cut an uncountable number of tunnels through bedrock and alluvium using hand tools and homespun solutions to problems that would vex the most experienced university-trained engineers. 200 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414347 / 9789402414349

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    EUR 117,69

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book primarily summarizes the imaging characteristics and theory of parasitic disease, offering a clinical guide and practical approach to understanding, preventing and diagnosing parasitic disease. Through imaging diagnosis and cross-research of imaging with autopsy and pathology, it highlights the chief characteristics and evolution of imaging, which provides primary scientific data for the understanding and research of parasitic disease. Divided into 9 chapters, this volume is fully illustrated with DR, CT and MRI images of different kinds of parasitic diseases, providing a valuable resource for radiologists in this field. 268 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414606 / 9789402414608

    Serie: Libro 14 de 17 - Theory and Applications of Transport in Porous Media

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    EUR 128,39

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book offers readers a comprehensive overview, and an in-depth understanding, of suitable methods for quantifying and characterizing saline aquifers for the geological storage of CO2. It begins with a general overview of the methodology and the processes that take place when CO2 is injected and stored in deep saline-water-containing formations. It subsequently presents mathematical and numerical models used for predicting the consequences of CO2 injection. This book provides descriptions of relevant experimental methods, from laboratory experiments to field scale site characterization and techniques for monitoring spreading of the injected CO2 within the formation. Experiences from a number of important field injection projects are reviewed, as are those from CO2 natural analog sites. Lastly, the book presents relevant risk management methods.Geological storage of CO2 is widely considered to be a key technology capable of substantially reducing the amount of CO2 released into the atmosphere, thereby reducing the negative impacts of such releases on the global climate. Around the world, projects are already in full swing, while others are now being initiated and executed to demonstrate the technology. Deep saline formations are the geological formations considered to hold the highest storage potential, due to their abundance worldwide. To date, however, these formations have been relatively poorly characterized, due to their low economic value. Accordingly, the processes involved in injecting and storing CO2 in such formations still need to be better quantified and methods for characterizing, modeling and monitoring this type of CO2 storage in such formations must be rapidly developed and refined. 576 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands, Springer Jul 2018, 2018

    940241441X / 9789402414417

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    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemaniabuchversandmimpf2000

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    EUR 106,99

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    Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume is a collection of research articles on the subject of solar flares and flares on other cool stars, which are currently extensively studied using new ground- and space-based instruments, together with highly sophisticated numerical simulations. The collection memorializes the work of a pioneer in the study of solar physics, Professor Zdenek ¿vestka (1925 Prague ¿ 2013 Bunschoten), a leading expert in the field of solar flares and the co-founder and Editor-in-Chief of the journal Solar Physics. The book contains many contributions to the conference ¿Solar and Stellar Flares: Observations, simulations and synergies¿, held in Prague during 23 ¿ 27 June 2014, organised in honor and memory of Professor ¿vestka.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 328 pp. Englisch. …

  • Idioma: Inglés

    Editorial: Springer Netherlands, Springer Netherlands Jul 2018, 2018

    9402414711 / 9789402414714

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    Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemaniabuchversandmimpf2000

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    Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The articles republished in this book survey and summarize recent research in helioseismology as well as studies of the interior structure, dynamics and magnetism of the solar interior that are being tested and refined using the helioseismic results.Helioseismology has in the last few decades become a highly productive technique for studying the Sun¿s interior from observations of the vibrations of its surface. The vibrations are manifestations of resonant modes of the Sun that are continuously excited by turbulent motions in the Sun¿s convection zone, and a plethora of data have been obtained from dedicated ground-based and space-based observing systems.The book will be of particular interest to researchers and graduate students in the fields of helioseismology, solar interior dynamics and the solar dynamo. It will also be of interest to researchers in solar physics, solar activity, stellar physics, astrophysical fluid dynamics and asteroseismology.Originallypublished in Space Science Reviews, Volume 196, Issue 1-4, December 2015Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 368 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414509 / 9789402414509

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    EUR 160,49

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The sirtuin family of proteins (SIRT1-7) received a lot of attention in recent years as they serve as metabolic sensors that control not only metabolism, but also aging and lifespan regulation. As such, sirtuins are strong targets for the treatment of age-related metabolic diseases, including obesity, diabetes, and cancer. Indeed, many research groups as well as pharmaceutical companies discovered food components and/or drugs that target the sirtuins and provide significant health benefits. This book focuses on various aspects of sirtuin biology, from basic biochemistry, via molecular function, to its role in (fighting) human disease. 296 pp. Englisch. …

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    940241407X / 9789402414073

    Serie: Libro 27 de 33 - Topics in Geobiology

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume addresses major evolutionary changes that took place during the Ediacaran and the Paleozoic. These include discussions on the nature of Ediacaran ecosystems, as well as the ichnologic signature of evolutionary radiations, such as the Cambrian explosion and the Great Ordovician biodiversification event, the invasion of the land, and the end-Permian mass extinction.This volume set provides innovative reviews of the major evolutionary events in the history of life from an ichnologic perspective. Because the long temporal range of trace fossils has been commonly emphasized, biogenic structures have been traditionally overlooked in macroevolution. However, comparisons of ichnofaunas through geologic time do reveal the changing ecology of organism-substrate interactions. The use of trace fossils in evolutionary paleoecology represents a new trend that is opening a window for our understanding of major evolutionary radiations and mass extinctions. Trace fossils provide crucial evidence for the recognition of spatial and temporal patterns and processes associated with paleoecologic breakthroughs. 376 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414002 / 9789402414004

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book focuses on early diagnosis and multidisciplinary treatment, which is the key to preventing the occurrence of the liver metastases in colorectal cancer, and to increasing the resection rate of the liver metastasis foci and the 5-year survival after surgery. This book is divided into five parts: the introduction, basics, diagnosis, treatment and prevention. It has 20 chapters in total, covering the latest advances in colorectal cancer liver metastases epidemiology, pathogenesis, molecular diagnostics, marker screening, imaging technology, surgery, chemotherapy and prevention, etc. It provides professionals with up-to-date and comprehensive information on colorectal liver metastases. This book is relevant for senior surgeons and physicians working in oncology, general surgery, chemotherapy, digestive medicine, liver medicine and hepatic surgery. 296 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414851 / 9789402414851

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This edited volume is about novel targeted therapies for the treatment of advanced neoplasms of the head and neck (HNSCC) with particular reference to oral squamous cell carcinomas and covers specific fields of cancer genetics and genomics for personalized medicine.The landmark studies from the HNSCC Cancer Genome Anatomy (TCGA) and the cancer Genome Atlas 2015 have revealed the multiplicity and diversity of genetic alterations in HNSCC. This remarkable body of information has elucidated novel druggable targets (eg. EGFR, mTOR, p53, survivin and aberrant microRNA) for therapeutic interventions in head and neck cancer.Readers will discover the importance of the biology and pathology of squamous cell carcinomas, the role of cancer stem cells and other factors that contribute to resistance to curative therapies such as hypoxia. We present an in-depth analysis of the HNSCC oncogenome describing the distinct molecular alterations in squamous cell carcinomas, which participate in specific molecular pathways whose dysregulation may contribute to most HNSCC cases. Final chapters of the book elucidate how these important cancer-driving molecular events and molecular pathways could be targeted to treat head and neck cancers and their therapeutic applications for targeted therapies based on clinical trials reported worldwide.This book is aimed at a broad audience, including scientists, physicians, surgeons, and post graduate students engaged in oncology and provide the readers with an up-to-date, interdisciplinary knowledge and tools to better understand the evolving areas of targeted gene therapy and the key concept of personalized medicine in head and neck cancer. 296 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414665 / 9789402414660

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book links tropical agri-chain dynamics - with which CIRAD and AFD have been involved for decades - to that of sustainable development. Increased environmental and social concerns urge agri-chain actors and development practitioners to design innovations, and public and private actors to invent regulations in connection with agri-chains to improve sustainability.With a view to contributing towards implementing the Sustainable Development Goals (SDGs), this book examines the different roles of agri-chains: as vectors of development, as spaces of innovation, as objects of evaluation, and as arenas of regulation. It builds upon the findings and experiences of CIRAD and its researchers together with their Southern partners, and of AFD and its officers.Linking agricultural production with the other economic sectors, agri- chains are key spaces where local and global challenges to sustainability meet and where local and global actors experiment interlinked or common solutions. 384 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414150 / 9789402414158

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book comprises26 articles on the EChO science cases, mission pre-assessment and assessment, phase-studies, the payload, the instrumentation and software. They arereprints of articles published in a special issue on EChO - Exoplanet Characterisation Observatory of the journal Experimental Astronomy.Originally published in Experimental Astronomy, Volume 40, Nos. 2-3 (2015) 524 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414177 / 9789402414172

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The reader will discover a comprehensive and multifaceted overview of the history of the development of anticancer drugs deeply influenced by the cell concept of cancer and future directions for the development of new anticancer drugs. First, this book documents the scientific progress in biological science over the last 70 years and the influence this progress had in cancer research. Summaries and charts of important discoveries complete this overview. Furthermore, this book outlines the process of anticancer drug development with a focus on the characteristic drug groups of each era, related to advancements of chemistry and biological sciences. This book also provides brief mechanism of action of drugs, illustrated by comprehensive timelines and conceptual cartoons. This book finally sums up the limitations of the current anticancer drug development and seeks new directions for anticancer drug discovery, considering under the systemic view of cancer. 296 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402415408 / 9789402415407

    Serie: Libro 133 de 151 - Solid Mechanics and Its Applications

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book covers both classical and modern analytical methods in nonlinear systems. A wide range of applications from fundamental research to engineering problems are addressed. The book contains seven chapters, each with miscellaneous problems and their detailed solutions. More than 100 practice problems are illustrated, which might be useful for students and researchers in the areas of nonlinear oscillations and applied mathematics. With providing real world examples, this book shows the multidisciplinary emergence of nonlinear dynamical systems in a wide range of applications including mechanical and electrical oscillators, micro/nano resonators and sensors, and also modelling of global warming, epidemic diseases, sociology, chemical reactions, biology and ecology. 304 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402413065 / 9789402413069

    Serie: Libro 25 de 28 - NATO Science for Peace and Security Series A: Chemistry and Biology

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book includes topics in nanophysics, nanotechnology, nanomaterials, sensors, biosensors, security systems, and CBRN agents detection. There have been many significant advances in the past two years and some entirely new directions of research are just opening up. Recent developments in nanotechnology and measurement techniques now allow experimental investigation of the physical properties of nanostructured materials. The book presents new methods for the detection of chemical, biological, radiological and nuclear (CBRN) agents using chemical and biochemical sensors. Identification, protection and decontamination are the main scientific and technological responses for the modern challenges of CBRN agents. 372 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402413030 / 9789402413038

    Serie: Libro 25 de 28 - NATO Science for Peace and Security Series A: Chemistry and Biology

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book includes topics in nanophysics, nanotechnology, nanomaterials, sensors, biosensors, security systems, and CBRN agents detection. There have been many significant advances in the past two years and some entirely new directions of research are just opening up. Recent developments in nanotechnology and measurement techniques now allow experimental investigation of the physical properties of nanostructured materials. The book presents new methods for the detection of chemical, biological, radiological and nuclear (CBRN) agents using chemical and biochemical sensors. Identification, protection and decontamination are the main scientific and technological responses for the modern challenges of CBRN agents. 372 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402413855 / 9789402413854

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This handbook is a valuable resource for scientists, engineers, graduate students, managers, decision makers, and those who are interested in ionic liquids. Many industrial applications rely on the use of Ionic Liquid Mixtures, as in solar energy storage, waste recycling or batteries.Physicochemical Properties of Ionic Liquid Mixtures is a useful handbook that contains the following features: - the physicochemical properties and property models of mixtures containing ionic liquids - supplemented by a comprehensive database of properties listing ionic liquid systems collected from more than 800 dependable literature sources - over 60,000 data entries on 39 types of physicochemical properties for 1388 mixtures, including binary, ternary, quaternary and other mixtures. 1132 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands, Springer Netherlands Jul 2018, 2018

    9402414045 / 9789402414042

    Serie: Libro 12 de 26 - World Soils Book

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    EUR 171,19

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The main objective of this book is to present the distribution and diversity of major soil types in Serbia. It focuses on giving a detailed description of the physical, chemical and biological properties of soil and their geomorphological forms, as well as the geological characteristics of parent material. An integrative approach is used to study the interaction between climate, vegetation and geology in soil formation. Special attention is paid to human-induced soil degradation due to the erosion and contamination of soils in Serbia. The book includes a harmonization of national soil classification systems, with the FAO, WBR and ESD systems. 244 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414371 / 9789402414370

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    EUR 181,89

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is an edited book with chapters written by multi-disciplinary specialists in their specific subject areas. It covers development of IPM components and packaging them for individual vegetable crops specifically targeted to tropical countries. Scientific background for IPM components or tactics will be included. There will be case studies of IPM packages developed and implemented in different countries. The concept of IPM has been in existence for the past six decades; however, a practical holistic program has not been developed and implemented for vegetable crops, in the developing countries. Currently the IPM adoption rate in the tropics is minimal and there is a need for implementation of IPM technologies that are environmentally safe, economical, and socially acceptable. We believe that adoption and implementation of IPM provided in this book will lead to significant reduction in crop losses and mitigate adverse impacts of pesticide use in the tropics. This book is an outcome 20 years of research, development and implementation of the IPM CRSP, a project supported by USAID and administered by Virginia Tech in several developing countries along the tropical belt in Africa, Asia, Latin America and the Caribbean. 324 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414746 / 9789402414745

    Serie: Libro 2 de 6 - Translational Medicine Research

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    EUR 181,89

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book offers a detailed overview of translational bioinformatics together with real-case applications. Translational bioinformatics integrates the areas of basic bioinformatics, clinical informatics, statistical genetics and informatics in order to further our understanding of the molecular basis of diseases. By analyzing voluminous amounts of molecular and clinical data, it also provides clinical information, which can then be applied. Filling the gap between clinic research and informatics, the book is a valuable resource for human geneticists, clinicians, health educators and policy makers, as well as graduate students majoring in biology, biostatistics, and bioinformatics. 448 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer Netherlands Jul 2018, 2018

    9402414703 / 9789402414707

    Serie: Libro 23 de 36 - RILEM State-of-the-Art Reports

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    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The work of the RILEM Technical Committee (TC -236 BBM) was dedicated to the study of construction materials made from plant particles. Itconsidered the question whether building materials containing as main raw material recyclable and easily available plant particles are renewable. This book includes a state-of-the-art report and an appendix. The state-of-the-art report relates to the description of vegetal aggregates. Then, hygrothermal properties, fire resistance, durability and finally the impact of the variability of the method of production of bio-based concrete are assessed. The appendix is a TC report which presents the experience of a working group. The goal was to define testing methods for the measurement of water absorption, bulk density, particle size distribution, and thermal conductivity of bio aggregates. The work is based on a first round robin test of the TC-BBM where the protocols in use by the different laboratories (labs) are compared.p> 300 pp. Englisch.…