springer basel springer basel jan 2012 (38 resultados)

Taschenbuch. Condición: Neu. Neuware -Although much of classical ergodic theory is concerned with single transformations and one-parameter flows, the subject inherits from statistical mechanics not only its name, but also an obligation to analyze spatially extended systems with multidimensional symmetry groups. However, the wealth of concrete and natural examples which has contributed so much to the appeal and development of classical dynamics, is noticeably absent in this more general theory. The purpose of this book is to help remedy this scarcity of explicit examples by introducing¿ a class of continuous Zd-actions diverse enough to exhibit many of the new phenomena encountered in the transition from Z to Zd, but which nevertheless lends itself to systematic study: the Zd-actions by automorphisms of compact, abelian groups. One aspect of these actions, not surprising in itself but quite striking in its extent and depth nonetheless, is the connection with commutative algebra and arithmetical algebraic geometry. The algebraic framework resulting from this connection allows the construction of examples with a variety of specified dynamical properties, and by combining algebraic and dynamical tools one obtains a quite detailed understanding of this class of Zd-actions.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 328 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -After Pyatetski-Shapiro[PS1] and Satake [Sa1] introduced, independent of one another, an early form of the Jacobi Theory in 1969 (while not naming it as such), this theory was given a de nite push by the book The Theory of Jacobi Forms by Eichler and Zagier in 1985. Now, there are some overview articles describing the developments in the theory of the Jacobigroupandits autom- phic forms, for instance by Skoruppa[Sk2], Berndt [Be5] and Kohnen [Ko]. We refertotheseformorehistoricaldetailsandmanymorenamesofauthorsactive inthistheory,whichstretchesnowfromnumbertheoryandalgebraicgeometry to theoretical physics. But let us only brie y indicate several¿ sometimes very closely related ¿ topics touched by Jacobi theory as we see it: ¿ eldsofmeromorphicandrationalfunctionsontheuniversalellipticcurve resp. universal abelian variety ¿ structure and projective embeddings of certain algebraic varieties and homogeneous spaces ¿ correspondences between di erent kinds of modular forms ¿ L-functions associated to di erent kinds of modular forms and autom- phic representations ¿ induced representations ¿ invariant di erential operators ¿ structure of Hecke algebras ¿ determination of generalized Kac-Moody algebras and as a nal goal related to the here rst mentioned ¿ mixed Shimura varieties and mixed motives. Now, letting completely aside the arithmetical and algebraic geometrical - proach to Jacobi forms developed and instrumentalized by Kramer [Kr], we ix x Introduction will treat here a certain representation theoretic point of view for the Jacobi theory parallel to the theory of Jacquet-Langlands [JL] for GL(2) as reported by Godement [Go2], Gelbart [Ge1] and, recently, Bump [Bu].Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 228 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -Many physical processes in fields such as mechanics, thermodynamics, electricity, magnetism or optics are described by means of partial differential equations. The aim of the present book is to demontstrate the basic methods for solving the classical linear problems in mathematical physics of elliptic, parabolic and hyperbolic type. In particular, the methods of conformal mappings, Fourier analysis and Green`s functions are considered, as well as the perturbation method and integral transformation method, among others. Every chapter contains concrete examples with a detailed analysis of their solution.The book is intended as a textbook for students in mathematical physics, but will also serve as a handbook for scientists and engineers.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 216 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -Eleven years have elapsed since the appearance of the first Volume and it is with great pleasure that the Editor is now able to present Volume 14. During these eleven years various fields of drug research have undergone important, partly revolutionary, changes. A number of these have already been dealt with, so that the series PROGRESS IN DRUG RESEARCH contains a comprehensive review of a substantial part of our current knowledge. The Editor is particularly grateful for the opportunity of transmitting to those connected with the development of drugs the extensive knowledge of the Authors, who, without exception, are themselves actively engaged in research. Drug research is currently in a state of transformation: reconsideration in the light of the past and reorientation with a view to the future. To a large extent this is due to the tumultuous developments in the last 20 years, developments which are unparalleled in the history of medicine and the consequences of which cannot yet be completely evaluated. Unfortunately, however, the current situation is not devoid of its unpleasant and even tragic aspects, aspects which fall outside the research worker's sphere or influence. Those connected with drug research, be they in industry, in universities or in clinics, are aware of these problems, and, as a result of this awareness, are all the more in need of an aid which will assist them in ascertaining the current position and in fixing future goals.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 588 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -This monograph brings together a collection of results on the non-vanishing of- functions.Thepresentation,thoughbasedlargelyontheoriginalpapers,issuitable forindependentstudy.Anumberofexerciseshavealsobeenprovidedtoaidinthis endeavour. The exercises are of varying di culty and those which require more e ort have been marked with an asterisk. The authors would like to thank the Institut d¿Estudis Catalans for their encouragementof thiswork throughtheFerranSunyeriBalaguerPrize.Wewould also like to thank the Institute for Advanced Study, Princeton for the excellent conditions which made this work possible, as well as NSERC, NSF and FCAR for funding. Princeton M. Ram Murty August, 1996 V. Kumar Murty xi Introduction Since the time of Dirichlet and Riemann, the analytic properties of L-functions have been used to establish theorems of a purely arithmetic nature. The dist- bution of prime numbers in arithmetic progressions is intimately connected with non-vanishing properties of various L-functions. With the subsequent advent of the Tauberian theory as developed by Wiener and Ikehara, these arithmetical t- orems have been shown to be equivalent to the non-vanishing of these L-functions on the line Re(s)=1. In the 1950¿s, a new theme was introduced by Birch and Swinnerton-Dyer. Given an elliptic curve E over a number eld K of nite degree over Q,they associated an L-function to E and conjectured that this L-function extends to an entire function and has a zero at s = 1 of order equal to the Z-rank of the group of K-rational points of E. In particular, the L-function vanishes at s=1ifand only if E has in nitely many K-rational points.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 208 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -Generalized Polygons is the first book to cover, in a coherent manner, the theory of polygons from scratch. In particular, it fills elementary gaps in the literature and gives an up-to-date account of current research in this area, including most proofs, which are often unified and streamlined in comparison to the versions generally known. Generalized Polygons will be welcomed both by the student seeking an introduction to the subject as well as the researcher who will value the work as a reference. In particular, it will be of great value for specialists working in the field of generalized polygons (which are, incidentally, the rank 2 Tits-buildings) or in fields directly related to Tits-buildings, incidence geometry and finite geometry. The approach taken in the book is of geometric nature, but algebraic results are included and proven (in a geometric way!). A noteworthy feature is that the book unifies and generalizes notions, definitions and results that exist for quadrangles, hexagons, octagons - in the literature very often considered separately - to polygons. Many alternative viewpoints given in the book heighten the sense of beauty of the subject and help to provide further insight into the matter.¿Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 520 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The tsunami from the 1960 Chilean earthquake affected the entire Pacific Ocean and motivated the international coordination of tsunami research and warning systems around the Pacific. However, the 2004 Indian Ocean tsunami affected the entire world, and reminded that tsunamis are not a local or regional problem but a global issue. This volume contains 15 papers, mostly presented at the 24th International Tsunami Symposium held on 14-16 July 2009 in Novosibirsk, Russia. They reflect the current state of tsunami science, including studies of recent tsunamis, tsunami statistics and warning, and modeling tsunami runup and inundation. 234 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -24. Marz 1994 -ein denkwiirdiges Datum: ein halbes Jahrtausend ist seit der Geburt eines Mannes vergangen, der jener Zeit in ganz besonderer Weise seinen Stempel aufdriickte und dies in der Absicht, Niitzliches, WertvoHes, Tiefgriindi ges, AuBergewohnliches zu schaffen. Goethe nannte ihn eine tilchtige und wohl um sich her schauende N atur, lobte ihn ob seiner Werke, welche den ganzen Kreis des alten und neuen Bergbaues, alter und neuer Erz-und Steinkunde umfassen und uns als ein kostliches Geschenk vorliegen. Welch schone Worte fur einen Menschen, dem das unverfalschte Erbe der Antike ebenso wichtig war wie die im Aufbruch befindliche Wissenschaft zu bereichem und in groBer Vielfalt gleichsam zu veredeln. Padagogik, lateinische und griechische Sprache, Philosophie, Medizin, Historiographie, Numismatik und Metrologie, Geologie und Mineralogie, Berg-und Hiittenwesen, Aufberei tung und Verfahrenstechnik - wer schuf in jener Zeit Vergleichbares und sol cherart Facettenreiches in wissenschaftlichem Denken und Wirken, zumal in groBem FleiBe niedergeschrieben und flir die N achwelt so auf ewig aufbewahrt In diesem Jahr steht dieser groBe sachsische Humanist und Renaissancege lehrte, dieser Riese an Denkkraft, Leidenschaft und Charakter, an Vielseitigkeit und Gelehrsamkeit, deutlicher denn je vor uns, gemahnt gleichermaBen an Gutes wie an urnfassende Bildung und Weisheit, nimmt uns auf neue Weise in die tagliche Pllicht.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 512 pp. Deutsch.

Taschenbuch. Condición: Neu. Neuware -This full-colour book assembles the proceedings papers of the ¿5th International Symposium on Lithographic Limestone and Plattenkalk¿, which was held 2009 at the Natural History Museum in Basel (Switzerland). The contributions are highlights from the Symposium and they are from active researchers and research groups. They cover a wide range of topics with the main focus on vertebrate palaeontology (Mesozoic fishes, sauropterygians, pterosaurs, artiodactyls) and invertebrate palaeontology (developmental biology of crustaceans, limulid locomotion, functional morphology of Saccocoma, trace fossils). In addition to this, other papers focus on palaeoenvironments and carbonate sedimentology (terminology & classification, role of microbial mats), as well as descriptions of new occurrences of Lithographic Limestone and Plattenkalk (Cambrian of China, Eocene of Croatia). The studied material includes exceptionally well-preserved fossils, classical palaeontological approaches (history of palaeontology, taxonomy with description of several new taxa, faunal reviews, tooth histology, Relative Warp Analysis, ichnology) and new methods such as composite-fluorescence imaging microscopy. The high diversity of these up-to-date papers highlights the importance of interdisciplinary scientific congresses and studies. Furthermore, it confirms that Lithographic Limestone and Plattenkalk deposits are amongst the most important Fossil Lagerstätten in the world and remain a major source for palaeobiological data. Therefore, the present book is a must for palaeontologists, palaeobiologists, and sedimentologists alike that are involved in studies of Lithographic Limestone and Plattenkalk Fossil Lagerstätten.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 188 pp. Englisch.

Buch. Condición: Neu. Neuware -Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions.Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 328 pp. Englisch.

Buch. Condición: Neu. Neuware -This special volume focuses on optimization and control of processes governed by partial differential equations. The contributors are mostly participants of the DFG-priority program 1253: Optimization with PDE-constraints which is active since 2006. The book is organized in sections which cover almost the entire spectrum of modern research in this emerging field. Indeed, even though the field of optimal control and optimization for PDE-constrained problems has undergone a dramatic increase of interest during the last four decades, a full theory for nonlinear problems is still lacking. The contributions of this volume, some of which have the character of survey articles, therefore, aim at creating and developing further new ideas for optimization, control and corresponding numerical simulations of systems of possibly coupled nonlinear partial differential equations. The research conducted within this unique network of groups in more than fifteen German universities focuses on novel methods of optimization, control and identification for problems in infinite-dimensional spaces, shape and topology problems, model reduction and adaptivity, discretization concepts and important applications. Besides the theoretical interest, the most prominent question is about the effectiveness of model-based numerical optimization methods for PDEs versus a black-box approach that uses existing codes, often heuristic-based, for optimization.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 636 pp. Englisch.

Buch. Condición: Neu. Neuware -Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. Development of recombinant human G-CSF has had a profound impact on the treatment of many diseases, including severe chronic neutropenia and cancer, and has enabled peripheral stem cell transplantation to supplant bone marrow transplantation in the autologous setting.This Milestones in Drug Therapy volume describes the experience of the last 20 years of treatment with recombinant human G-CSF, including the basic science, the use of recombinant human G-CSF in both the oncology and nononcology settings, and the safety and economics of its use. Many of the authors were the original investigators of recombinant human G-CSF and other authors are key researchers who provide their outlook for the next 20 years for use of and research with recombinant human G-CSF.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 500 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -Unter den Gattungen der antiken Literatur ist nach Jahren der Ver nachUissigung in der letzten Zeit ein besonderes Interesse am griechisch romischen Roman festzustellen. Die vom 27. -31. Marz 1995 im Centro Stefano Franscini von den beiden Unterzeichnenden organisierte Tagung wollte diesem neu erwachten Interesse in zweifacher Weise gerecht wer den: Einerseits wollten wir ein Forum bieten, urn die oft kontroversen Forschungsstandpunkte zu diskutieren und dadurch eventuell neue Mog lichkeiten des Zugangs zu den erzahlenden Texten der Antike zu erOff nen, andrerseits sollten die vielfaltigen Beziehungen zwischen den antiken und mittelalterlichen Erzahlformen in interdisziplinarer Zusammenarbeit von Klassischen Philologen, Byzantinisten, Mediavisten und Romanisten erhellt werden. Die in dem vorliegenden Band publizierten Beitrage, die Uberarbeiteten Fassungen der auf dem Monte Verita gehaltenen Vortrage, belegen, so hoffen wir, die auBerst ertragreiche und anregende Zusam menarbeit der verschiedenen an der Tagung beteiligten literaturwissen schaftlichen Disziplinen. An dieser Stelle seien einige Worte des Dankes gestattet: Dem Centro Stefano Franscini und der ETH ZUrieh sei gedankt flir die Gastfreund schaft, die uns auf dem Monte Verita zuteil wurde, und fUr die Uberaus groBzUgige finanzielle UnterstUtzung, ohne die die Tagung nie hatte statt finden konnen. Frau Katia Bastianelli hat durch ihren nie ermUdenden Einsatz den reibungslosen Ablauf der Tagung moglich gemacht. Die ZUr cher Mitarbeiter, Tatiana Crivelli und Johannes Bartuschat, haben sich sowohl im Vorfeld der Tagung als auch in der redaktionellen Arbeit am vorliegenden Tagungsband selbstlos eingesetzt.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 364 pp. Deutsch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Diese Einführung in die algebraische Geometrie richtet sich an Studierende mittlere und höhere Semester. Vorausgesetzt werden lediglich die im ersten Studienjahr erworbenen Grundkenntnisse. Ausgehend von den affinen Hyperflächen werden beliebige affine und schliesslich projektive Varietäten untersucht. Die benötigte Algebra wird dabei laufend entwickelt. Schwerpunkte des Buches sind die Dimensions- und Morphismentheorie, die Multiplizitätstheorie sowie der Gradbegriff. Zahlreiche Beispiele sollen dem Leser helfen, sich über die konkrete Bedeutung des Stoffes klarzuwerden. 470 pp. Deutsch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volumes 18 and 19 of 'Progress in Drug Research' differed from the earlier volumes insofar as they were concerned almost exclusively with problems in the field of Tropical Medicine. The editor and publishers believed that in this way some contribution could be made to the solution of some of the many problems with which the developing countries are burdened. The 20th volume, however, is in the customary form; it contains 17 contributions from various areas of drug research and therapy. Whereas the articles concentrate on a short representation of the progress which has already been made, nevertheless reference is also made to the many unsolved problems within the particular areas. The editor hopes that the 20th volume will not only represent a comprehensive review but will also be of some use in focusing further investigations on problems of medicine that have still not been overcome. The editor would also like to take this opportunity of expressing his gratitude to Dr. A. Naffor carefully working over the manuscripts and correcting proofs. Thanks are also due to the publishers and the printers, Druckerei Birkhauser, especially Dr. A. Birkhauser, Th. Birkhauser and C. Einsele, for their painstaking work on the printing and lay-out of the volume. August 1976 Dr. E. JUCKER Sandoz AG, Basel Vorwort Die Bande 18 und 19 der 'Fortschritte der Arzneimitte1forschung' wichen insofern von den vorhergehenden Banden ab, a1s sie fast ausschliess1ich Prob1eme der Tropenkninkheiten behandelten. 632 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The 19th volume deals, as did its predecessor, with current problems of tropical medicine. Both volumes are based on various international Symposia which were held in Bombay on the occasion of the 75-year Platinum Jubilee of the Haffkine Institute in the Spring of 1974. The contributions in the 19th volume are based on lectures at thetast three Symposia which dealt with Helminthiasis, Diphtheria, Pertussis, Tetanus and Cholera. The 70 articles provide the reader with an impressive cross-section of the current state of specialized knowledge on the subject and the outstanding problems. Even today, researchers from various disciplines are still confronted with numerous unsolved problems in tropical medicine, and it is to be hoped that the 18th and 19th volumes will provide a stimulus for intensified research in the area of tropical medicine. The editor further hopes that, in the future, a still more fruitful co-operation between developed and developing countries will come about. The editor owes special thanks to Dr. Rafiq Zakaria, Minister, Dr. Gaitonde, as well as Dr. Anand and Dr. Chadha, who were responsible for the organisa tion of the Symposia on which the 19th volume is based. Thanks are also extended to Dr. A. Niif for his conscientious revision of the manuscripts and correction of the galley proofs. In addition, thanks are due to the publishers and the printers, Birkhiiuser, especially to Dr. A. Birkhiiuser, Th. Birkhauser and C. Einsele for their accurate printing and fine presentation of the volume. 656 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 24 includes six contributions, the author and paper index of volumes 1-24 and the key-word index. Since volume 23 included an index for volumes 16-23 the reader has the possibility to use these monographs as an encyclopedia and is in the position to find references to almost all fields of drug research. The editor hopes that the articles of the present volume will prove interesting and useful to many scientists and would be grateful to receive suggestions and opinions from readers, as in the past case over the 20 years in which this series of monographs has existed. In this respect, thanks are due to all colleagues who have provided helpful criticism of past volumes, thereby helping the editor in his work. Dr. A. Naf again has assisted the editor and has carefully reviewed all manuscripts, formulae and references, and has corrected the proofs. Thanks are due to him for this immense work. At the same time, the editor would like to thank the publishers and printers, Verlag Birkhliu ser, in particular Messrs. Th. Birkhliuser and C. Einsele, for the excellent cooperation and the work they have accomplished. 412 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 480 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present 18th volume differs from previous volumes insofar as, with the exception of two contributions, it is exclusively concerned with problems of a single field, namely Tropical Medicine. This was occasioned by the Internatio nal Symposium on the investigation and treatment of infectious tropical diseases held in Bombay in January 1974 and organized by the editor in collaboration with the Minister of Health of the State of Maharashtra, Dr. Rafiq Zakaria, the Director of the Hafl'kine Institute, Dr. B. Gaitonde, and with Dr. J. N. Banerjee, Dr. S. K. Bhattacharya and Mr. P. D'Souza. The Hafl'kine Institute celebrated on this occasion the 75th year of its existence and everyone entrusted with the organisation of the Symposium considered themselves fortunate to have been able to help in strengthening the contacts between Indian and foreign research workers, in the hope of, in this way, making a contribution to the fight against infectious tropical diseases. The editor hopes that the present 18th volume will represent comprehensive information on the topics treated at the Symposium; the 19th volume, which will soon appear, is concerned with the same area, so that the two volumes together should give a good picture of the many still unsolved problems. The editor would also like to take this opportunity of expressing his gratitude to his collaborator, Dr. A. Niif, who, as usual, performed valuable services in working over the manuscripts. 498 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 22 of 'Progress in Drug Research' contains 8 contributions from vari ous areas of drug research and therapy. As in previous volumes, in the present volume the authors have also tried not only to summarize the current status of particular fields of drug research, but also to provide leads for future research activity. The various contributions in this volume will be of especial value not only to those actively concerned in resolving the diverse problems in drug research, but also to those who wish to keep abreast of the latest developments influencing modem therapy. In addition, it is believed that volume 22 and the previous 21 volumes of 'Progress in Drug Research' so far published represent a useful reference work of an encyclopaedic character. The editor would also like to take this opportunity of expressing his gratitude to those who reviewed the previous volumes of this series of monographs and, by doing so gave useful advice for the future volumes. At the same time, thanks are expressed to Dr. A. Naf for carefully working over the manuscripts and correcting proofs. Thanks are also due to the publishers and the printers, Druckerei Birkhauser, especially to Messrs. Th. Birkhauser and C. Einsele. Unfortunately, this is the last volume which went into ptess during Dr. A. Birkhauser's lifetime; he passed away on March 4, 1978 and the editor would like to stress the fact'tl;tat. 412 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 41 of 'Progress in Orug Research' contains eight reviews and the various indexes which facilitate its use and establish the con nection with the previous volumes. The articles in this volume deal with teratogenesis; nephrotoxicity; bacterial resistance to P. lactam antibiotics; eradication of diseases by vaccination; chirality and drug design; endogenous digitalis-like factors; erythropoietin; and sero tonin (5HT)-antagonists. 3 All these articles give an excellent overview of the respective fields of research. In the 33 years that POR has existed, the Editor has enjoyed the valu able help and advice of many colleagues. Readers, the authors of the reviews, and last but not least, the reviewers have all contributed greatly to the success of this series. Although the comments received so far have generally been favorable, it is nevertheless necessary to analyze and to reassess the current position and the future direction of such a review series. So far, it has been the Editors intention to help disseminate informa tion on the vast domain of drug research, and to provide the reader with a tool with which to keep abreast of the latest developments and trends. The reviews in POR are useful to the non-specialists, who can obtain an overview of a particular field of research in a relatively short time. The specialist readers of POR will appreciate the reviews' comprehensive bibliographies, and, in addition, they may even get fresh impulses for their own research. 406 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 21 of 'Progress in Drug Research' contains 5 contributions from various areas of drug research and therapy. As in previous volumes, in the present volume the authors have also tried not only to summarise the current status of particular fields of drug research, but also to provide leads for future research activity. The various contributions in this volume will be of especial value not only to those actively concerned in resolving the diverse problems in drug research, but also to those who wish to keep abreast ofthe latest developments in fluencing modem therapy. In addition, it is believed that volume 21 and the previous 20 volumes of 'Progress in Drug Research' so far published represent a useful reference work of an encyclopaedic character. The editor would also like to take this opportunity of expressing his gratitude to Dr. A. Naffor carefully working over the manuscripts and correcting proofs. Thanks are also due to the publishers and the printers, Druckerei Birkhauser, especially to Dr. A. Birkhauser, Th. Birkhiiuser and C. Einsele, for their painstaking work on the printing and lay-out of the volume. August 1977 Dr. E. JUCKER Sandoz AG, Basel Vorwort Der 21. Band der 'F ortschritte der Arzneimittelforschung' umfasst 5 Beitriige aus verschiedenen Gebieten der Arzneimittelforschung und der Therapie. 500 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 40 of 'Progress in Drug Research' contains six reviews and the various indexes which facilitate its use and establish the connec tion with the previous volumes. The articles in this volume deal with phosphodiesterase inhibitors and their therapeutic potential in asthma; peptide receptor ligand drugs; aldose reductase inhibitors; the design and discovery of new drugs by stepping-down and stepping-up approaches; new synthetic ligands for L-type voltage gated calcium channels and with luteolytic agents in fertility regula tion. III the 33 years that 'Progress in Drug Research' has existed, the Edi tor has enjoyed the valuable help and advice of many colleagues. Readers, the authors of the reviews, and last but not least, the review ers have all contributed greatly to the success of this series. Although the comments received so far have generally been favorable, it is nevertheless necessary to analyze and to reassess the current position and the future direction of such a review series. 312 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 27 of 'Progress in Drug Research' contains 5 articles, a subject index for this volume, an alphabetic subject 4ldex for volumes 1-27, and an author and subject index for altthe volumes which have so far been published. The contributions of volume 27 are particularly concerned with fungal disease, with benzimidazole anthelmintics and with the chemistry and pharmacology of quinuclidines, azoles, and nitroimida zoles. The authors have tried, not only to summarize the current status of particular fields of drug research, but also to provide leads for future research activity. The articles of this volume will be of special value to those actively engaged in drug research, and to those who wish to keep abrest of the latest developments influencing modem therapy. In addi tion, it is believed that the 27 volumes of 'Progress in Drug Research' now available represent a useful reference work of encyclopedic charac ter. The editor would like to take the occasion of the publication of this volume to express his gratitude both to the authors and to the readers. The authors have willingly1undertaken'the great labor of writing signifi cant topical contributions, hnd many readers have helped the editor with criticism and advise. With these thanks, the editor would like also to express his gratitude to the publisher, Birkhauser Verlag Basel, particu larly to Messrs. Th. Birkhauser and C. Einsele, and their associates for the excellent cooperation. 426 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 28 of 'Progress in Drug Research' contains 8 articles, a subject index for this volume, an alphabetic subject index for volumes 1-28, and an author and subject index for all the volumes which have so far been published. The contributions of volume 28 are particularly con cerned with biogenic amines, with immunology and the pharmacology of the immune system, with antiviral agents, with amino-quinoline an timalarials, with the axoplasmic transport, with drug treatment of asthma and with the role of adipose tissue in the distribution and stor age of drugs. The authors have tried, and I think they have succeded, not only to summarize the current status of particular fields of drug research, but also to provide leads for future research activity. The articles of this volume will be of special value to those actively engaged in drug re search, and to those who wish to keep abrest ofthe latest developments influencing modern therapy. In addition, it is believed that the 28 volu mes of 'Progress in Drug Research' now available represent a useful reference work of encyclopedic character. l The editor would like to take the bccasion of the publication of this volume to express his gratitude both to ,the authors and to the readers. 346 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 26 of 'Progress in Drug Research' contains 10 articles, a subject index for this volume, an alphabetic subject index for volumes 1-26, and an author and subject index for all the volumes which have so far been published. The contributions of volume 26 cover a wide field of drug research and therapy, and some are directed towards tropical deseases. As in previous volumes, the authors have also tried not only to summa rise the current status of particular fields of drug research, but also to provide leads for future research activity. The articles in this volume will be of special value not only to those actively engaged in resolving the diverse problems in drug research, but also to those who wish to keep abrest of the latest developments influencing modern therapy. In addition, it is believed that the 26 volumes of 'Progress in Drug Research' now available represent a useful reference work of an encyclo paedic character. 412 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Tiergerechte Haltungsformen gewinnen erfreulicherweise und aus vielerlei Grunden zu nehmend an Gewicht. Die Entwicklung wird von sehr unterschiedlichen Menschen und Gruppen vorangetrieben. Verhaltensforscher erarbeiten deren Grundlagen. Es gilt namIich herauszufinden, welche Haltungssysteme im Sinne der darin lebenden Tiere als tiergerecht bezeichnet werden konnen, wo Kompromisse moglich sind und welche Haltungsformen abgelehnt werden miissen. Es gilt aber auch herausZufinden wie Stane beschaffen sein soll ten, in denen Menschen im Rahmen ihrer taglichen Arbeit mit den Nutztieren umgehen. Zu fragen sind daher die Tiere und die Tierhalter. Die vorliegende Schrift ist aus einer am Fachbereich Landwirtschaft der Gesamthochschule Kassel in Witzenhausen angefertigten Diplomarbeit hervorgegangen. Am Anfang stand das Engagement des Autors fUr die Belange der Milchkiihe. Es ~eIang das Niitzliche mit dem Angenehmen zu verbinden und das Interesse an ethologlschen Fragen in eine Diplomarbeit als AbschluB des landwirtschaftlichen Studiums einzubringen. Gediingt wurde die Pflanze mit dem Humus der Kenntnisse, die sich auf den verschiedenen Gebieten der landwirschaftlichen Tierhaltung angesammelt hatten. Die berechtigten Forderungen der Praxis sorgten schlieBlich dafiir, daB die Baume nicht in den Himmel wuchsen. So ist ein Leitfaden entstanden, der mithelfen kann, den Wunsch nach tiergerechter Milchviehhaltung etwas besser zu erfiillen. Wer Verbesserungen, Umbauten oder gar einen Neubau plant, wird zahlreiche Anregun gen finden. Wer sich, aus welchen Grunden auch immer, informieren will, kann dies mit Gewinn tun. Der Leser wird schnell gewahr werden, wie vielschichtig die Synthese aus dem Verhalten von Milchkiihen, den daraus abgeleiteten Grundre~eln des Stallbaus und den Beurteilungskriterieen der Tierschutzgesetzgebung in der Wirkllchkeit ist. 108 pp. Deutsch, Englisch.