iste ltd gb (Más de 1.300 resultados)

Paperback. Condición: New.

Hardback. Condición: New. Predictive microbiology primarily deals with the quantitative assessment of microbial responses at a macroscopic or microscopic level, but also involves the estimation of how likely an individual or population is to be exposed to a microbial hazard.This book provides an overview of the major literature in the area of predictive microbiology, with a special focus on food. The authors tackle issues related to modeling approaches and their applications in both microbial spoilage and safety.Food spoilage is presented through applications of best-before-date determination and commercial sterility. Food safety is presented through applications of risk-based safety management. The different modeling aspects are introduced through probabilistic and stochastic approaches, including model and data uncertainty, but also biological variability.

Paperback. Condición: New.

Hardback. Condición: New. Statistics for Bioinformatics: Methods for Multiple Sequence Alignment provides an in-depth introduction to the most widely used methods and software in the bioinformatics field. With the ever increasing flood of sequence information from genome sequencing projects, multiple sequence alignment has become one of the cornerstones of bioinformatics. Multiple sequence alignments are crucial for genome annotation, as well as the subsequent structural, functional, and evolutionary studies of genes and gene products. Consequently, there has been renewed interest in the development of novel multiple sequence alignment algorithms and more efficient programs.

Hardback. Condición: New. Traffic Anomaly Detection presents an overview of traffic anomaly detection analysis, allowing you to monitor security aspects of multimedia services. The author's approach is based on the analysis of time aggregation adjacent periods of the traffic. As traffic varies throughout the day, it is essential to consider the concrete traffic period in which the anomaly occurs. This book presents the algorithms proposed specifically for this analysis and an empirical comparative analysis of those methods and settle a new information theory based technique, named "typical day analysis".

Paperback. Condición: New.

Hardback. Condición: New. Plants and animals have evolved ever since their appearance in a largely microbial world. Their own cells are less numerous than the microorganisms that they host and with whom they interact closely. The study of these interactions, termed microbial symbioses, has benefited from the development of new conceptual and technical tools. We are gaining an increasing understanding of the functioning, evolution and central importance of symbiosis in the biosphere. Since the origin of eukaryotic cells, microscopic organisms of our planet have integrated our very existence into their ways of life. The interaction between host and symbiont brings into question the notion of the individual and the traditional representation of the evolution of species, and the manipulation of symbioses facilitates fascinating new perspectives in biotechnology and health. Recent discoveries show that association is one of the main properties of organisms, making a more integrated view of biology necessary.Microbial Symbioses provides a deliberately "symbiocentric outlook, to exhibit how the exploration of microbial symbioses enriches our understanding of life, and the potential future for this discipline.

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Hardback. Condición: New. Emergy presents the fundamentals of emergy, proposing the definition and representation of emergy diagrams and 'spreading.' Embodied energy is the energy consumed by all of the processes associated with the production of a building, from the mining and processing of natural resources to manufacturing, transport and product delivery. The authors evaluate a range of sources and the methodologies surrounding emergy analysis. Filled with real-world applied examples including wood energy, wind resources, ore and recycling, this book shows you how to adopt an approach similar to the Lagrangian approach to fluid mechanics, and establish that the intuitive notion of temporal independence of the emergy specific to materials requires nuances.

Hardback. Condición: New. Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis.Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which total synthesis has been achieved. This book presents the isolation and preparation of these two compounds and their analogues through various synthesis strategies. Details of the structural elements essential to their anti-cancer activity are presented, with the objective of explaining and optimizing their biological activities and potential development as drugs.

Paperback. Condición: New.

Hardback. Condición: New. This book presents the research that resulted from a fruitful collaboration between many CNRS research laboratories, health establishments and industrialists. This research contributes to the study and the development of logistical systems, in particular health-oriented logistical systems, in order to manage and optimize physical, informational and financial flows. The authors examine optimization and modeling methods to facilitate decision support for the management of logistics systems in the health field, including solutions to problems encountered in the management of logistics flows and the study of systems incorporating these flows. In the first chapter, logistics engineering is presented whilst the second chapter introduces the study of real cases of transport, management crisis and warehouse management logistics systems. The third chapter is devoted to the study of hospital systems and emergency services and in the fourth chapter, the authors highlight the operational aspect of the hospital system thanks to an innovative modeling approach. Finally, mathematical and algorithmic models of scheduling, and dynamic orchestration of the collaborative workflow by a multi-agent system, are introduced.

Paperback. Condición: New.

Hardback. Condición: New. Predictive microbiology primarily deals with the quantitative assessment of microbial responses at a macroscopic or microscopic level, but also involves the estimation of how likely an individual or population is to be exposed to a microbial hazard.This book provides an overview of the major literature in the area of predictive microbiology, with a special focus on food. The authors tackle issues related to modeling approaches and their applications in both microbial spoilage and safety.Food spoilage is presented through applications of best-before-date determination and commercial sterility. Food safety is presented through applications of risk-based safety management. The different modeling aspects are introduced through probabilistic and stochastic approaches, including model and data uncertainty, but also biological variability.

Hardback. Condición: New. This book presents a crisis scenario generator with black swans, black butterflies and worst case scenarios. It is the most useful scenario generator that can be used to manage assets in a crisis-prone period, offering more reliable values for Value at Risk (VaR), Conditional Value at Risk (CVaR) and Tail Value at Risk (TVaR). Hazardous Forecasts and Crisis Scenario Generator questions how to manage assets when crisis probability increases, enabling you to adopt a process for using generators in order to be well prepared for handling crises.

Paperback. Condición: New.

Hardback. Condición: New. Cultural heritage is increasingly recognized for its contributions to the transition to climate action, and heritage education can play an important role in developing climate adaptation competencies. These can foster positive dialogs surrounding climate change, shift attitudes and inspire actions. However, achieving these goals requires bridging the gap between policy, practice and local capacity building, as well as integrating a multi- and transdisciplinary approach into traditional higher education curricula and models. Bringing together knowledge, practice and experiences from different disciplinary silos, this book provides a wide set of innovative teaching and learning methods, tools and pedagogical models that can be adapted to heritage education in order to address climate issues. Organized into four parts, Heritage Education for Climate Action covers a wide array of international experiences, real-life cases and practices, focusing on heritage and resilience building, vulnerability and risk assessment, climate change adaptation, mitigation and policymaking. This book is therefore a source of suggestions and ideas for scholars, educators and professionals who want to develop future climate leadership and contribute to the transition of heritage education toward sustainable development and climate action.

Hardback. Condición: New. Statistics for Bioinformatics: Methods for Multiple Sequence Alignment provides an in-depth introduction to the most widely used methods and software in the bioinformatics field. With the ever increasing flood of sequence information from genome sequencing projects, multiple sequence alignment has become one of the cornerstones of bioinformatics. Multiple sequence alignments are crucial for genome annotation, as well as the subsequent structural, functional, and evolutionary studies of genes and gene products. Consequently, there has been renewed interest in the development of novel multiple sequence alignment algorithms and more efficient programs.

Hardback. Condición: New. This book presents a short introduction to continuous-time financial models. An overview of the basics of stochastic analysis precedes a focus on the Black-Scholes and interest rate models. Other topics covered include self-financing strategies, option pricing, exotic options and risk-neutral probabilities. Vasicek, Cox?Ingersoll?Ross, and Heath-Jarrow-Morton interest rate models are also explored.The author presents practitioners with a basic introduction, with more rigorous information provided for mathematicians. The reader is assumed to be familiar with the basics of probability theory. Some basic knowledge of stochastic integration and differential equations theory is preferable, although all preliminary information is given in the first part of the book. Some relatively simple theoretical exercises are also provided.

Hardback. Condición: New. Traffic Anomaly Detection presents an overview of traffic anomaly detection analysis, allowing you to monitor security aspects of multimedia services. The author's approach is based on the analysis of time aggregation adjacent periods of the traffic. As traffic varies throughout the day, it is essential to consider the concrete traffic period in which the anomaly occurs. This book presents the algorithms proposed specifically for this analysis and an empirical comparative analysis of those methods and settle a new information theory based technique, named "typical day analysis".

Hardback. Condición: New. This book addresses the high performance computing of the Discrete Element Model (DEM). It is a comprehensive presentation of parallel implementation of the DEM on three popular parallel computing platforms; the multi-core PC, the GPU computer, and the cluster supercomputer. Featuring accompanying MatLab source this book helps you implement the DEM model for use with high performing technology, for particular implementation of the dynamic failure of solids, granular flow and stress wave propagation through solids.

Hardback. Condición: New. Health Industrialization discusses the way healthcare professionals distinguish between medicine, surgery, and diet and lifestyle guidelines. In other words, the ways that medicine aims to provide quantity of life. Men and women would rather remain in good health as long as possible and compensate for the deficiencies that crop up to the best of their abilities. Hence, they are looking for quality of life that results in tensions brought on by different objectives. This book hypothesizes that this tension is the cause of an industrialization of medicine or health that depends to a degree on the point-of-view we choose.

Hardback. Condición: New. Qualitative Analysis of Nonsmooth Dynamics: A Simple Discrete System with Unilateral Contact and Coulomb Friction explores the effects of small and large deformations to understand how shocks, sliding, and stick phases affect the trajectories of mechanical systems. By analyzing these non-regularities successively this work explores the set of equilibria and properties of periodic solutions of elementary mechanical systems, where no classical results issued from the theory of ordinary differential equations are readily available, such as stability, continuation or approximation of solutions. The authors focus on unilateral contact in presence of Coulomb friction and show, in particular, how any regularization would greatly simplify the mathematics but lead to unacceptable physical responses.

Paperback. Condición: New.

Hardback. Condición: New. Divided Solids Mechanics, part of the Industrial Equipment for Chemical Engineering set, defines how to perform the selection and calculation of equipment needed in the basic operations of process engineering, offering reliable and simple methods, with this volume providing a comprehensive focus divided solids mechanics. Throughout these concise and easy-to-use books, the author uses his vast practical experience and precision knowledge of global research to present an in-depth study of a variety of aspects within the field of chemical engineering.

Hardback. Condición: New. Faced with the exponential development of Big Data and both its legal and economic repercussions, we are still slightly in the dark concerning the use of digital information. In the perpetual balance between confidentiality and transparency, this data will lead us to call into question how we understand certain paradigms, such as the Hippocratic Oath in medicine. As a consequence, a reflection on the study of the risks associated with the ethical issues surrounding the design and manipulation of this "massive data seems to be essential.This book provides a direction and ethical value to these significant volumes of data. It proposes an ethical analysis model and recommendations to better keep this data in check. This empirical and ethico-technical approach brings together the first aspects of a moral framework directed toward thought, conscience and the responsibility of citizens concerned by the use of data of a personal nature.

Hardback. Condición: New. Our world overwhelms us with more and more data everyday. Yet we need to face many challenges in order to deal with its complexity - notably to discern the essential from the accessory, to exploit quality and not quantity, to explore the depth of our knowledge and to produce from it, in a reasoned way, effective ideas to be put into action. A synthesis of a triple experience in industry, pedagogy and academia, Knowledge and Ideation presents numerous concepts, such as the dematerialized knowledge object, inventive intellectual heritage, inventive potential, and knowledge-based ideation. This book develops and describes applications in the form of case studies while proposing prospects.

Hardback. Condición: New. It took nearly four billion years for the Earth to become a hospitable planet. Archean and Proterozoic Earth traces the geodynamic, biological, climatic and environmental upheavals that accompanied this evolution. This book looks at the planet's secular cooling and its implications for the dynamics of the Earth's mantle and the development of plate tectonics, as well as the evolution of magma composition and the formation of a differentiated continental crust. It shows how variations in the intensity of the Earth's magnetic field have proved useful in reconstructing the movement of continents across the surface of the globe. The book also documents the origin of the oceans and the appearance of the first traces of life, and describes the evolution of the major biogeochemical cycles that led to the oxygenation of the atmosphere, the diversification of living organisms and the concentration of substances of economic interest, particularly metals.

Hardback. Condición: New. Among the many forms of cancer treatment, chemotherapy remains an important part of the arsenal in which Navelbine and Taxotere play a major role.These medicines result from molecules discovered by French researchers of the Institut de Chimie des Substances Naturelles (ICSN) of the CNRS, directed by Pierre Potier. By recounting this history, the authors of this book attempt to illustrate how the work of themselves and others, united in a community, has helped obtain these results. After having explained the strategy of the French policy makers to promote the French chemistry of natural substances, the authors explore how the academic efforts in this field have evolved, and the alignment between science and its applications has become increasingly present. The contributions of the CNRS to the industry, and vice versa, offer an alternative image of public research relationships and industrial research, where CNRS researchers are able to extend the limits of freedom and creativity. It is to account for this complexity that the authors here have chosen to write this history together, which is in a sense exemplary.Due to an association between history and chemistry, this book explains these discoveries by placing them in their specific politic, economic and scientific contexts.

Paperback. Condición: New.