elsevier science jan 2000 (8 resultados)

Taschenbuch. Condición: Neu. Neuware - In 1999, the IFAC/IFIP Workshop on Real Time Programming (WRTP) joined forces with the Workshop on Active and Real-Time Database Systems (ARTDB). Both series of workshops provide a forum for exchanging information on recent scientific and technological advances and practices in real time computing.

Taschenbuch. Condición: Neu. Neuware - This practical guide for managers addresses the rationale of a drug- free workplace, policy requirements, drug testing, and treatment. It includes step-by-step guidance for establishing programs and includes checklists, sample policies and program aids, and numerous resource listings. Fay was a special agent of the U.S Army Criminal Investigation Division (CID) and later the Director of the National Crime Prevention Institute at the University of Louisville.

Buch. Condición: Neu. Neuware - Genetic Aberrancies and Neurodegenerative Disorders presents critical reviews and emerging findings concerning the roles of genetic mutations and polymorphisms in the pathogenesis of a range of neurological disorders including Alzheimer's and Parkinson's diseases, trinucleotide repeat disorders, stroke, epilepsy and others. This volume, written by leading experts, brings together fundamental information concerning the roles of inherited traits in the pathogenesis of different neurodegenerative disorders. In addition to providing a catalogue of the known genetic alterations that are linked to specific neurodegenerative disorders, the chapters detail the current state of understanding of the cellular and biochemical mechanisms whereby the genetic aberrancies lead to neuronal dysfunction and degeneration. The emerging picture of each disorder, painted by pathological, biochemical and molecular brushes, suggests that they share key mechanisms including increased levels of oxidative stress, perturbed ion homeostasis, mitochondrial dysfunction and apoptotic proteolytic cascades. The existence of specific molecular defects provides the opportunity to design experiments that can establish the precise pathogenic mechanism of a specific mutation or genetic risk factor. The value of this approach is exemplified by recent studies of how mutations in Cu/Zn-superoxide dismutase cause amyotrophic lateral sclerosis and how presenilin mutations result in early-onset Alzheimer's disease. A theme developed among the different chapters is that events that occur during aging predispose neurons to genetic aberrancies that promote degenerative cascades, and that specific genetic defects exert their influenceon particular populations of neurons in a disorder-specific manner. The chapters in this volume will stimulate readers to generate new hypotheses concerning the pathogenic mechanisms of genetic aberrancies that can be experimentally tested.

Buch. Condición: Neu. Neuware - The present volume focuses on microbial invasion strategies of pathogen uptake. An accompanying volume (Vol. 5) in the series presents the phagocytic process from the viewpiont of the host cell. This field of study is growing rapidly after a somewhat slow start over recent decades. This collection of invited chapters attempts to reflect current research and brings together cell biologists, microbiologists, and immunologists wiht disthemes, hopefully like a symphony rather than a boring catalogue. It will be evident that editorial bias favors intracellular parasitism and medically important organisms. The neutrophil is far more than a supporting player to the macrophage and some attempt is made to remind the reader of some of its unique skills. To retain a manageable size, the emphasis is on relatively early events such as mutual recognition, cell entry, and response, rather than on longterm changes in gene expression by either host cell or pahtogen. Viruses are excluded not because of lack of importance but because of somewhat different research approaches, although it is becoming increasingly clear that large viruses (e.g. Vaccinia) and Listeria monocytogenes, share common strategies in invasion and intercellular spread.

Buch. Condición: Neu. Neuware - This volume presents work from six different groups working on various aspects of cycloaddition chemistry. Jose Mascarenas gives us a very interesting account of the chemistry of &Bgr;-alkoxy-&ggr;-pyrones and related species. Al Padwa and Chris Staub discuss further advances in rhodium carbenoid chemistry and the unusual cycloaddition processes possible with these intermediates. Higher order cycloadditions mediated by transition metals highlight Jim Rigby's update on his group's efforts in this area. Lily Lee and John Snyder present us with a detailed account of the indole ring as a dienophile, challenging us to consider the untapped potential in this area. Brian Keay and Ian Hunt discuss the intramolecular Diels-Alder reactions of furan; a report that is both top-notch science, and what could be a great learning tool for students who need to see how fundamental chemical principles can and should be applied to synthetic problems. Finally, Kay Brummond introduces us to a new version of the Pauson-Khand reactions, one that will no doubt be further exploited in productive ways by her group well into the future.

Buch. Condición: Neu. Neuware - Trent (University of Birmingham) and Wright (University of California, Berkeley) introduce the essential features of metal cutting, and the roles played by forces and stresses, heat, materials, and coolants and lubricants. The fourth edition adds four chapters that reflect the trend towards high speed machining of aerospace and other difficult-to-machine alloys, and the use of the computer to support analytical and computer modeling of cutting.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The field of statistical physics has undergone a spectacular development in recent years. The fundamentals of the subject have advanced dynamically with multidisciplinary approaches involving physicists, chemists and mathematicians. Equally spectacular has been the development of applications of statistical mechanics to shed light on a wide range of problems, many of them arising in fields quite distant from traditional physics disciplines. Recent applications range from such topics as oil recovery from porous rock to protein folding, DNA structure, morphogenesis and the cooperative behavior of living creatures. Concepts and methods of statistical physics have been applied successfully to 'exotic' problems that seem to be far from physics, such as vehicular and pedestrial traffic, or economy and finance. This book presents not only the keynote invited talks, but a number of high quality, interesting, contributed communications from senior scientists and young students active in the field. Topics covered include DNA migration, wetting, chemical waves, granular media, molecular motors, biological pattern formation and motion, as well as practical problems such as heart diagnosis, internet traffic jamming, oil recovery and econophysics. 400 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Elsevier's Dictionary of Mathematics contains 11,652 entries with more than 4,750 cross-references. Selection of the terms was based either on their significance or on their frequency of use according to authoritative encyclopedias, dictionaries and textbooks. Included are both modern developments and contemporary changes in terminology as well as recently established terms. The terminology covers all the major branches from elementary to advanced subjects: arithmetic, algebra, geometry, set theory, discrete mathematics, logic, Boolean algebra, linear algebra, matrix algebra, calculus, differential equations, vector algebra, field theory, probability theory and statistics, optimization, numerical methods, mathematical programming, modern algebra, algebraic structures, computer algebra, category theory, applied mathematics, theory of automata and formal languages, theory of games, theory of graphs, as well as some commonly used entries in computer architecture, hardware, communications, system and application software, microprogramming, etc. This work will provide readers, writers and translators with a guide of the most widely used terms and collections in the area, and will prove to be a useful tool for all professionals exploring the multilingual scientific terminology. 1008 pp. Englisch.