Transient Receptor Potential Channels (Advances in Experimental Medicine and Biology)

Oversized hardcover, xxiii + 1095 pages, colour illustrations in text, NOT ex-library. Yellow highlighting on 40 pages. A short pen line in side margin of one page, two lines on p.857. Other pages are clean. 6 straightened page corner folds. Binding is loosened but secure and stable. Boards show storage wear: scratches, two small areas of surface damage (rear panel), a couple of scuff-marks on lower edges, shelfwear. Published without a dust jacket. -- Contents: Structural Biology of TRP Channels; Functional and Structural Studies of TRP Channels Heterologously Expressed in Budding Yeast; Natural Product Ligands of TRP Channels; Synthetic Modulators of TRP Channel Activity; Study of TRP Channels by Automated Patch Clamp Systems; TRPC2: Of Mice But Not Men; TRPM1: New Trends for an Old TRP; Non-selective Monovalent Cationic Channels TRPm4 and TRPM5; TRPM7, the Mg2+ Inhibited Channel and Kinase; TRPM8 in Health and Disease: Cold Sensing and Beyond; TRPML1; TRPML2 and the Evolution of Mucolipins; TRPML3 Channel: From Gene to Function; TRPV5 and TRPV6 in Transcellular Ca2+ Transport: Regulation, Gene Duplication, and Polymorphisms in African Populations; TRPV5 Promoter as a Tool for Generation of Transgenic Mouse Models; TRPP Channels and Polycystins; TRP Channels in Yeast; C. elegans TRP Channels; Investigations of the In Vivo Requirements of Transient Receptor Potential Ion Channels Using Frog and Zebrafish Model Systems; TRP Channels in Parasites; Receptor Signaling Integration by TRP Channelsomes; Gating Mechanisms of Canonical Transient Receptor Potential Channel Proteins: Role of Phosphoinositols and Diacylglycerol; TRPC Ion Channels: Association with Orail and STIMI1 Proteins and Participation in Capacitative and Non-capacitative Calcium Entry; Contribution of TRPc1 and Orail to Ca2+ Entry Activated by Store Depletion; Primary Thermosensory Events in Cells; Thermo-TRP Channels: Biophysics of Polymodal Receptors; Complex Regulation of TRPv1 and Related Thermo-TRPs: Implications for Therapeutic Intervention; Voltage Sensing in Thermo-TRP Channels; TRP Channels as Mediators of Oxidative Stress; Regulation of TRP Signalling by Ion Channel Translocation Between Cell Compartments; Emerging Roles of Canonical TRP Channels in Neuronal Function; TRP Channels and Neural Persistent Activity; Role of TRP Channels in Pain Sensation; TRPV1: A Therapy Target That Attracts the Pharmaceutical Interests; Expression and Function of TRP Channels in Liver Cells; Expression and Physiological Roles of TRP Channels in Smooth Muscle Cells; TRPM Channels in the Vasculature; Molecular Expression and Functional Role of Canonical Transient Receptor Potential Channels in Airway Smooth Muscle Cells; TRP Channels in Skeletal Muscle: Gene Expression, function and Implications for Disease; TRP Channels in Vascular Endothelial Cells; TRP Channels in the Cardiopulmonary Vasculature; TRP Channels of Islets; Multiple Roles for TRPs in the Taste System: Not Your Typical TRPs; Roles of Transient Receptor Potential Proteins (TRPs) in Epidermal Keratinocytes; TRP Channels in Urinary Bladder Mechanosensation; Role of TRP Ion Channels in Testicular Function; TRP Channels in Female Reproductive Organs and Placenta; Oncogenic TRP Channels; TRPV Channels in Tumor Growth and Progression; Role of Transient Receptor Potential Channels in Respiratory Symptoms and Pathophysiology; TRP Channels and Psychiatric Disorders; Transient Receptor Potential Genes and Human Inherited Disease; Index.…