Presents the basic principles of time-of-flight mass spectrometry with an emphasis on applications in biological research. It describes many innovative techniques including orthogonal extraction, post-source decay, and delayed extraction. It also surveys ionization techniques used on TOF mass spectrometers such as electron impact, plasma desorption, SIMS, FAB, laser desorption, MALDI, and electrospray. The book features two timely chapters on the applications of TOF mass spectrometry to peptides/proteins, oligonucleotides, and other biological macromolecules, and covers how the techniques might be used in sequencing the human genome. Annotation c. by Book News, Inc., Portland, Or.

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This book presents the basic principles of time-of-flight (TOF) mass spectrometry with a strong emphasis on applications in biological research. It describes many innovative techniques, including orthogonal extraction, post source decay, and delayed extraction, and surveys ionization techniques used on TOF mass spectrometers such as electron impact, plasma desorption, SIMS, FAB, laser desorption, MALDI, and electrospray. The book features chapters on applications to peptides/proteins, oligonucleotides, and other biological macromolecules, and examines how techniques might be used in sequencing the human genome.

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