Theranostic Applications of Nanotechnology in Neurological Disorders

This book comprehensively reviews the theranostic applications of nanomaterials against various neurological disorders. The initial chapters briefly introduce various neurological disorders, their molecular mechanism, available treatments, and the latest research. It further reviews the challenges associated with the current theranostics strategies, including blood-brain-barrier. This book examines the synthesis of nanoparticles, development of efficient biosensors, fabrication of nanomaterials, diagnosis through nano-chips, and their interaction with neuronal cells. The chapter also discusses the various nanoformulations or nanocarriers of natural therapeutics, including herbal products, peptides, nootropics, and dietary supplements used to prevent and delay neurological disorders. Additionally, the book provides information on the commonly used molecular imaging tools and biosensors, using different nanomaterials for the early detection of neurological disorders. Towards the end,the book covers the imaging techniques like gold nanocages and photoacoustic imaging for diagnosing and targeted drug delivery for neurological disorders. The chapter presents the current challenges in using nanotechnology for neurological disorders and their potential solutions.

Dr. Akash Gautam is an assistant professor at the Centre for Neural and Cognitive sciences, School of Medical Sciences, University of Hyderabad, India, since 2013. He earned his PhD from department of zoology, Banaras Hindu University, India. His research interest is in neuroscience with a specialization in the neurobiology of learning and memory, molecular mechanisms of neurodegenerative disorders, synthesis of nanoformulations and herbal therapeutics for neurological disorders. He has been conferred several awards, including the International Brain Research Organization, the International Society for Neurochemistry, and the Department of Science and Technology, India. He has more than ten years of teaching experience for inter-disciplinary courses like cognitive science, biochemistry, research methodology & statistics, and molecular neuroscience. He has also published various research articles in the peer-reviewed international journal, a few book and book chapters. He is a member of many international scientific societies and organizations, notably the Indian Science Congress Association, Indian Academy of Neurosciences, Society of Biological Chemists, India, Society for Neurosciences, Molecular and Cellular Cognition Society, International Society for Neurochemistry, Society for Neurochemistry, India.

Dr. Vishal Chaudhary is an assistant professor of physics at the University of Delhi since 2015, and a visiting associate professor at chemical engineering department, University of Johannesburg, South Africa. He has obtained his doctorate in condensed nano-matter physics from the department of physics and astrophysics, University of Delhi, New Delhi, India. His research interests include nanomaterials, green nanotechnology, sensors, environmental remediation, one health and non-invasive diagnosis. He has published various research articles, and a few books and and book chapters. He has been listed in top 2% scientist in world and awarded with many prestigious awards including Agents of Change Award 2023 and SDG Service Award 2021. He is a member of various scientific advisory committees, associate editor/editorial board member of prestigious journals, and served as convenor of the research cell of the institution for two consecutive years.