Studies on Retinal and Choroidal Disorders

Idioma: inglés

Editorial: Humana Press, Humana Press Apr 2014, 2014

1627039600 / 9781627039604

Serie: Libro 8 de 25 - Oxidative Stress in Applied Basic Research and Clinical Practice

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This item is printed on demand - Print on Demand Titel. Neuware -Studies on Retinal and Choroidal Disorders examines the role that oxidative and nitrosative stress plays in the complex physiology and pathophysiology of the retina and choroid. Both the basic science researcher and the clinical practitioner can use this book as a guide to the current understanding of retinal and choroidal cellular mechanisms involved in aging and disease. Beginning with a review of oxidative stress and inflammation in the pathoetiology of AMD and a review of the complement system in the retina, the book then takes a detailed look at oxidative stress in lipid metabolism and oxidized lipoproteins in the retina. It examines the anti-apoptotic activity of ¿-crystallins in the presence of glutathione, oxidative stress in the mitochondria and endoplasmic reticulum, the role of iron in retinal disease, the mechanisms of pathological VEGF expression, NAPDH oxidase mechanisms, and Hepatocyte Growth Factor in oxidative stress in the retina.A detailed look at the Ccl2-/-/Cx3cr1-/- mouse model of AMD follows. Then a detailed examination of the systemic changes in AMD is followed by a discussion of cerium oxide nanoparticle reduction of oxidative stress. Two chapters discuss progenitor cells in the cause and treatment of retinal diseases including AMD and diabetic retinopathy. Natural compounds in the prevention and treatment of retinal diseases are exhaustively presented, followed by a chapter on serotonin 5-HT1A receptor agonists in oxidative stress of the retina. The current anti-VEGF treatment strategies of neovascular AMD are then given. The volume continues with a detailed look at nitric oxide and inducible nitric oxide synthase in retinal vascular disease, an explanation of an in vivo technique of studying the effect of lipid hydroperoxides on circulating leucocytes in the retina, an excellent review of oxidative stress in retinopathy of prematurity, and a look at VEGFinduced oxidative stress in the retinal ganglion cell. The book ends with a detail examination of the role of carotenoids in retinal health and disease. These 31 chapters summarize what is known about oxidative stress in retinal and choroidal disorders. All those involved with degenerative diseases of the eye will find Studies on Retinal and Choroidal Disorders to be illuminating and comprehensive.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 660 pp. Englisch.…

N° de ref. del artículo 9781627039604

Título
Studies on Retinal and Choroidal Disorders
Autor
Robert D. Stratton
Editorial
Humana Press, Humana Press Apr 2014
Año de publicación
2014
Estado
Neu
Encuadernación
Taschenbuch
Idioma
inglés
ISBN 10
1627039600
ISBN 13
9781627039604
Peso del artículo
984 gramos
Dimensiones
235x155x36 mm
Serie
Libro 8 de 25: Oxidative Stress in Applied Basic Research and Clinical Practice

buchversandmimpf2000

Emtmannsberg, BAYE, Alemania

Vendedor de 5 estrellas

Vendedor de IberLibro desde 23 de enero de 2017

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