Studies on Retinal and Choroidal Disorders
. Ed(s): Stratton, Robert D.; Hauswirth, William W.; Gardner, Thomas W. (Penn State University College of Medicine)
Idioma: inglés
Editorial: Humana Press Inc., 2012
Serie: Libro 8 de 25 - Oxidative Stress in Applied Basic Research and Clinical Practice
- Tapa dura
- Nuevo
Librería: Kennys Bookshop and Art Galleries Ltd., Galway, GY, IrlandaKennys Bookshop and Art Galleries Ltd.
Vendedor de IberLibro desde 27 de febrero de 2001
Condición: Nuevo
EUR 255,88
Cantidad disponible: 15 disponibles
Añadir al carritoDescripción del artículo del vendedor
This book examines the role that oxidative and nitrosative stress plays in the physiology and pathophysiology of the retina and choroid. It serves as the ideal guide to understanding the retinal and choroidal cellular mechanisms involved in aging and disease. Editor(s): Stratton, Robert D.; Hauswirth, William W.; Gardner, Thomas W. (Penn State University College of Medicine). Series: Oxidative Stress in Applied Basic Research and Clinical Practice. Num Pages: 644 pages, 8 colour tables, biography. BIC Classification: MJQ. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 41. Weight in Grams: 1148. . 2012. Hardback. . . . .
N° de ref. del artículo V9781617796050
- Título
- Studies on Retinal and Choroidal Disorders
- Autor
- . Ed(s): Stratton, Robert D.; Hauswirth, William W.; Gardner, Thomas W. (Penn State University College of Medicine)
- Editorial
- Humana Press Inc.
- Año de publicación
- 2012
- Estado
- New
- Encuadernación
- Encuadernación de tapa dura
- Idioma
- inglés
- ISBN 10
- 1617796050
- ISBN 13
- 9781617796050
- Serie
- Libro 8 de 25: Oxidative Stress in Applied Basic Research and Clinical Practice
Studies on Retinal and Choroidal Disorders examines the role that oxidative and nitrosative stress plays in the complex physiology and pathophysiology of the retina and choroid. Both the basic science researcher and the clinical practitioner can use this book as a guide to the current understanding of retinal and choroidal cellular mechanisms involved in aging and disease. Beginning with a review of oxidative stress and inflammation in the pathoetiology of AMD and a review of the complement system in the retina, the book then takes a detailed look at oxidative stress in lipid metabolism and oxidized lipoproteins in the retina. It examines the anti-apoptotic activity of α-crystallins in the presence of glutathione, oxidative stress in the mitochondria and endoplasmic reticulum, the role of iron in retinal disease, the mechanisms of pathological VEGF expression, NAPDH oxidase mechanisms, and Hepatocyte Growth Factor in oxidative stress in the retina.
A detailed look at the Ccl2-/-/Cx3cr1-/- mouse model of AMD follows. Then a detailed examination of the systemic changes in AMD is followed by a discussion of cerium oxide nanoparticle reduction of oxidative stress. Two chapters discuss progenitor cells in the cause and treatment of retinal diseases including AMD and diabetic retinopathy. Natural compounds in the prevention and treatment of retinal diseases are exhaustively presented, followed by a chapter on serotonin 5-HT1A receptor agonists in oxidative stress of the retina. The current anti-VEGF treatment strategies of neovascular AMD are then given. The volume continues with a detailed look at nitric oxide and inducible nitric oxide synthase in retinal vascular disease, an explanation of an in vivo technique of studying the effect of lipid hydroperoxides on circulating leucocytes in the retina, an excellent review of oxidative stress in retinopathy of prematurity, and a look at VEGF induced oxidative stress in the retinal ganglion cell. The book ends with a detail examination of the role of carotenoids in retinal health and disease. These 31 chapters summarize what is known about oxidative stress in retinal and choroidal disorders. All those involved with degenerative diseases of the eye will find Studies on Retinal and Choroidal Disorders to be illuminating and comprehensive.
“Sinopsis” puede pertenecer a otra edición de este título.
Acerca del autor
Robert D Stratton, MD is the Founder of Erie Retinal Surgery from 1984 to 2008 and past Head of the Division of Retinal Surgery, Department of Ophthalmology, University of Florida School of Medicine from 1980 to 1984 . He is a fellow of the American Board of Ophthalmology, the American Academy of Ophthalmology, and the American College of Surgeons. Dr. Stratton's interests include vitreous and retinal diseases and surgery, and has 30 years experience in clinical practice. He is currently Courtesy Assistant Professor in the Department of Ophthalmology, University of Florida and Adjunct Assistant Professor in the Division of Small Animal Clinical Sciences, School of Veterinary Medicine, University of Florida.
William W Hauswirth , PhD, is the Rybaczki-Bullard Professor of Ophthalmology and Molecular Genetics at the University of Florida College of Medicine. Dr. Hauswirth is, in part, responsible for determining the mechanism of replication of adeno-associated virus (AAV) DNA and the discovery of mitochondrial DNA heteroplasmy in mammals, the basis of mitochondrial disease. He collaborated on the first successful rescue of a dominant genetic disease in animals and the first restoration of vision for a recessive retinal disease. He also demonstrated that AAV mediated gene therapy could cure red-green color blindness in monkeys. Dr Hauswirth’s current interests involve the delivery and testing of potentially therapeutic genes for many eye diseases in natural and transgenic animal models of human disease.
Thomas W. Gardner is Professor of Ophthalmology and Visual Sciences and Molecular and Integrative Physiology at the University of Michigan in Ann Arbor, Michigan. He was previously the Jack and Nancy Turner Professor of Ophthalmology and Cellular and Molecular Physiology at the Penn State College of Medicine. Dr. Gardner’s interests include vitreoretinal diseases and surgery, and clinical and experimental diabetic retinopathy. He currently serves as Associate Editor of Diabetes and Acta Ophthalmologica and on the editorial board of the Journal of Ocular Biology, Diseases and Informatics. He served previously on the editorial board of Diabetes, and is the former Editor-in-Chief of Current Eye Research.
“Acerca de” puede pertenecer a otra edición de este título.
Kennys Bookshop and Art Galleries Ltd.
Galway, GY, Irlanda
Vendedor de IberLibro desde 27 de febrero de 2001
Tarifas de envío de Irlanda a Estados Unidos de America
| Artículo | De 12 a 22 días hábiles | De 10 a 20 días hábiles |
|---|---|---|
| Primer artículo | EUR 9,50 | EUR 11,50 |
Métodos de pago
Descripción de la tienda
Kennys.ie is the largest exporter of books from Ireland currently exporting to approximately 100 countries around the world. Kennys Bookshop houses hundreds of thousands of books and specialises in collection development and library services, supplying booksellers and state and university libraries on a global scale including the U.S.A.,Japan and Europe. Kennys.ie is Ireland's Largest Online Bookshop.
Especialidad
Asia, All Aspects of the Irish Experience, Irish Literature, Irish History, Human Rights, International Espionage, History of Ideas and Human Thought, Labour History, Jewish Studies and the Holocaust. Gureilla Movements., Russian and Soviet History and Literature. Womens Studies and Feminism.Información empresarial del vendedor
Kennys Bookshop and Art Galleries (Holdings) Limited
Liosbán Retail Park, Tuam Road
Galway, Irlanda H91 N5P8
Condiciones de venta
Terms of Sale - Credit Cards: Visa, Master Card, American Express, Diner.
Payment can also be made by bank draft in Euros, drawn on an Irish Bank.
We regret that PO Boxes are not acceptable to the U.S. as our courier will not deliver to them.
In case of returns or queries please contact us by email books@kennys.ie or by phone +353 91 709350
VAT Registration - IE2238521A
Conor Kenny
Derecho al desistimiento
Si es un consumidor, puede rescindir el contrato de acuerdo con lo siguiente. Por consumidor se entiende cualquier persona física que actúe con fines ajenos a su actividad comercial, empresarial, oficio o profesión.
Información sobre el derecho de desistimiento
Derecho legal de desistimiento
Tiene derecho a rescindir este contrato en un plazo de 14 días sin dar ningún motivo.
El periodo de desistimiento vencerá a los 14 días desde que usted, o un tercero que no sea el transportista e indicado por usted, adquiera la posesión física del último bien o del último lote o pieza.
Para ejercer el derecho de desistimiento, complete de forma electrónica y envíe una declaración clara en nuestro sitio web, desde "Mis compras" en "Mi cuenta". Le enviaremos sin demora un acuse de recibo de dicho desistimiento a través de un soporte duradero (por ejemplo, por correo electrónico).
Para cumplir con el plazo de desistimiento, basta con que envíe su comunicación relativa al ejercicio del derecho de desistimiento antes de que venza el periodo de desistimiento.
Efectos del desistimiento
Si rescinde este contrato, le reembolsaremos todos los pagos que hayamos recibido de usted, incluidos los gastos de envío (excepto los gastos adicionales que surjan si elige un tipo de envío que no sea el tipo de envío estándar más económico que ofrecemos).
Podemos hacer una deducción del reembolso por la pérdida de valor de cualquier bien suministrado, si la pérdida es el resultado de una manipulación innecesaria por su parte.
Efectuaremos el reembolso sin demoras indebidas y, a más tardar, 14 días después de que se nos informe de su decisión de rescindir este contrato.
Efectuaremos el reembolso utilizando el mismo medio de pago que utilizó para la transacción inicial, a menos que haya acordado expresamente lo contrario; en cualquier caso, no incurrirá en ningún cargo como resultado de dicho reembolso.
Podremos retener el reembolso hasta que hayamos recibido los bienes o hasta que nos haya presentado una prueba de que los ha devuelto, lo que ocurra primero.
Deberá devolver los bienes o entregarlos a Kennys Bookshop and Art Galleries Ltd., Galway, GY, Ireland, sin demoras indebidas y, en cualquier caso, en un plazo máximo de 14 días a partir del día en que nos comunique su desistimiento del presente contrato. El plazo se cumple si devuelve la mercancía antes de que venza el periodo de 14 días. Tendrá que asumir los gastos directos de devolución de los bienes. Usted solo es responsable de la disminución del valor de los bienes como resultado de una manipulación distinta a la necesaria para establecer la naturaleza, las características y el funcionamiento de los bienes.
Excepciones al derecho de desistimiento
El derecho de desistimiento no se aplica a lo siguiente:
- La entrega de periódicos, diarios o revistas, con la excepción de los contratos de suscripción; y
- El suministro de contenido digital que no se proporcione en un soporte tangible (por ejemplo, en un CD o DVD) si, al hacer el pedido, aceptó que podíamos empezar a entregarlo y que no podría desistir una vez iniciada la entrega.
Condiciones de envío
Free Shipping