Statistical Methods for Environmental Mixtures

Idioma: inglés

Editorial: Springer Nature Switzerland, Springer International Publishing Jan 2025, 2025

3031789865 / 9783031789861

Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides a comprehensive introduction to statistical approaches for the assessment of complex environmental exposures, such as pollutants and chemical mixtures, within the exposome framework. Environmental mixtures are defined as groups of 3 or more chemical/pollutants, simultaneously present in nature, consumer products, or in the human body. Assessing the health effects of environmental mixtures poses several methodological challenges due to the high levels of correlation that are often present between environmental chemicals, and by the need of incorporating flexible non-additive and non-linear effects that can capture and describe the complex mechanisms by which environmental exposure contribute to diseases. Several statistical approaches are proposed and discussed, including the application of regression-based approaches (e.g. penalized regression such as LASSO and elastic net, or Bayesian variable selection) for environmental exposures, and novel methods (e.g. weighted quantile sum regression, or Bayesian Kernel Machine Regression) that account for specific complexities of environmental exposures. More recent efforts included are the application of machine learning approaches (e.g. gradient boosting) for environmental data.Statistical Methods for Environmental Mixtures describes the statistical challenges that commonly arise when dealing with environmental exposures and provides an introduction to different statistical approaches for such data. Over the last decade, substantial efforts have been made to transition the statistical framework for environmental exposures in epidemiologic studies from a single-chemical/pollutant to a multi-chemicals/pollutants approach. This book provides a comprehensive introduction to this modern multi-chemicals/pollutants framework. Emphasis is given to interpretability, discussing issues with causal interpretation and translation of scientific finding when applying the discussed statistical approaches for complex environmental exposures.The target audience includes researchers in environmental epidemiology and applied statisticians working in the field. As such, while rigorously presenting the statistical methodologies, the book keeps an applied focus, discussing those settings where each method is appropriate for use and for which question it can be applied, providing examples of accurate presentation and interpretation from the literature, including a basic introduction to R packages and tutorials, as well as discussing assumptions and practical challenges when applying these techniques on real data. 112 pp. Englisch.…

N° de ref. del artículo 9783031789861

Título
Statistical Methods for Environmental Mixtures
Autor
Andrea Bellavia
Editorial
Springer Nature Switzerland, Springer International Publishing Jan 2025
Año de publicación
2025
Estado
Neu
Encuadernación
Buch
Idioma
inglés
ISBN 10
3031789865
ISBN 13
9783031789861
Peso del artículo
340 gramos
Dimensiones
241x160x12 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Alemania

Vendedor de 5 estrellas

Vendedor de AbeBooks desde el 11 de enero de 2012

Tarifas de envío de Alemania a Estados Unidos de America

ArtículoDe 5 a 15 días hábilesDe 5 a 15 días hábiles
Primer artículoEUR 23,00EUR 23,00
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BuchWeltWeit Ludwig Meier e.K.

Alemania