Sleep Disorders Part 1 offers a glimpse of developments that focus on diagnostic techniques in the field of neurobiology of sleep. This part discusses the models of the rapid eye movement (REM) sleep mechanism; issues regarding sleep states, stages, and memory consolidation; and advances in the understanding of the sleep-wake genes, gene products, the circadian clock, and the role of sleep duration. This book explains noninvasive neuroimaging studies, particularly positron emission tomographic and single photon emission computed tomographic scans. It further discusses advances in clinical science, including concepts about neurobiology of sleep, narcolepsy-cataplexy, therapy, and laboratory techniques. The significant advances in therapy have led to the addition of new drugs for the treatment of different sleeping disorders, as described in this book. Sleep is essential to humans. Awareness of its true importance leads to the development and acceptance of sleep medicines in the market.
Since the late 90 s, a renewed interest in the neurobiology of sleep has provided new advancements in the understanding of basic sleep science and the clinical aspects of sleep disorders, with particular interest given to the role of genetics.
From laboratory techniques and therapies, groundbreaking research in sleep-wakefulness, new models of rapid eye movement (REM) sleep mechanisms, to bright light therapy for circadian rhythm sleep disorders, this handbook will provide clinicians and researchers with a state-of-the-art reference that summarizes the clinical features and management of the many neurological manifestations of sleep disorders.
Practitioners will find invaluable research, information, and laboratory techniques on such topics as sleep-wake-dependent genes, the role of sleep duration in mortality and morbidity, and advancements in the understanding of the neurobiology of sleep disorders, including narcolepsy-cataplexy, restless legs syndrome, REM behavior disorders, fatal familiar insomnia, sleep apnea and heart failure, and nocturnal paroxysmal dystonia, amongst others. In addition, significant advancements in therapies and drug protocols are presented.