Prusa CORE One+ (Gen 2) User Guide: Complete Beginner-to-Advanced Manual for Setup, Printing, Calibration, and Maintenance

Prusa CORE One+ (Gen 2) User Guide

Complete Beginner-to-Advanced Manual for Setup, Printing, Calibration, and Maintenance

Ready to get more from your Prusa CORE One+ (Gen 2)?

Whether you are setting up your printer for the first time, learning how to achieve reliable first layers, experimenting with advanced materials, or building a repeatable 3D-printing workflow, this practical user guide is designed to take you from the fundamentals to more advanced techniques.

The Prusa CORE One+ (Gen 2) User Guide provides a clear, practical approach to understanding the printer, preparing materials, configuring PrusaSlicer, calibrating your machine, improving print quality, troubleshooting common problems, and maintaining the printer for long-term use.

Inside This Guide, You’ll Learn How To:

Understand the CORE One+ (Gen 2) architecture, CoreXY motion system, Nextruder, heated bed, enclosure, and major components

Unbox, assemble, configure, and perform essential initial checks

Navigate the printer interface and configure basic settings

Update firmware and connect the printer through available network options

Perform automatic calibration and optimize first-layer performance

Choose and prepare PLA, PETG, ASA, ABS, and other commonly used filaments

Load, unload, and change filament correctly

Set up PrusaSlicer and select appropriate printer and material profiles

Import, position, orient, and prepare 3D models for printing

Understand layer height, infill, supports, brims, speed, temperature, and other important print settings

Slice, preview, and send projects to the printer

Create your first successful print and evaluate the finished result

Improve calibration, layer consistency, adhesion, cooling, and surface quality

Optimize enclosed-chamber printing for temperature-sensitive materials

Improve results with ABS and ASA

Balance printing speed, strength, reliability, and surface quality

Understand advanced multi-material workflows and the INDX system

Manage multiple filaments and material changes

Prevent common multi-material printing problems

Establish practical cleaning and preventive-maintenance routines

Maintain the Nextruder, nozzle, nozzle wiper, belts, fans, and motion components

Diagnose common problems such as poor adhesion, stringing, warping, layer shifting, and extrusion issues

Build reliable personal print profiles for different applications

Organize filaments, projects, and PrusaSlicer profiles

Prepare the CORE One+ (Gen 2) for long prints and consistent production

Develop a repeatable workflow for dependable, professional-looking results

Designed for Practical Learning

This is not intended to be a collection of complicated technical explanations. The information is organized around the actual workflow of using a modern 3D printer—from preparing the machine and filament to slicing a model, starting a print, evaluating the result, and maintaining the equipment afterward.

Beginners can use the early chapters to establish a solid foundation, while experienced makers can use the calibration, advanced-material, multi-material, troubleshooting, and optimization sections as a practical reference.

Whether you are interested in 3D printing, rapid prototyping, functional parts, product development, engineering models, custom designs, or everyday maker projects, this guide can help you build a more organized and reliable printing workflow.