Proteomics Today: Protein Assessment and Biomarkers Using Mass Spectrometry, 2D Electrophoresis, and Microarray Technology

Proteomics Today (Hardcover)

Hardcover. Condición: new. Hardcover. The last few years have seen an unprecedented drive toward the application of proteomics to resolving challenging biomedical and biochemical tasks. Separation techniques combined with modern mass spectrometry are playing a central role in this drive. This book discusses the increasingly important role of mass spectrometry in proteomic research, and emphasizes recent advances in the existing technology and describes the advantages and pitfalls as well. * Provides a scientifically valid method for analyzing the approximatey 500,000 proteins that are encoded in the human genome * Explains the hows and whys of using mass spectrometry in proteomic analysis * Brings together the latest approaches combining separation techniques and mass spectrometry and their application in proteome analysis * Comments on future challenges and how they may be addressed * Includes sections on troubleshooting The latest and most effective uses of mass spectrometry, 2D electrophoresis, and microarray technology for protein analysis The first step in analyzing complex biochemical systems involves determining the molecular masses of interacting proteins, peptides, and other components. Proteomics, the study of all proteins expressed by a genome, calls for a powerful tool—mass spectrometry—to identify these proteins. A full understanding of the vital role of mass spectrometry in proteomic research necessitates an illuminating text like "Proteomics Today," Over the last several years, new emphasis has been placed on the application of proteomics to perform demanding biomedical and biochemical tasks. "Proteomics Today" clearly describes the contributions of the latest approaches—separation techniques, modern mass spectrometry, two-dimensional electrophoresis, and microarray technology—in meeting these challenges. The emerging roles of imaging mass spectrometry and protein interaction maps are also addressed. In this single comprehensive source, you will find an invaluable examination of all the newest technologies related to: Instrumentation Current strategies for protein quantification SDS-gel electrophoresis Conventional isoelectric focusing in gel matrices, capillaries, and immobilized pH gradients Two-dimensional maps Proteomics in cancer research A must-have guide for scientists and laboratory technicians who study proteins in the pharmaceutical and biotechnology industries, "Proteomics Today" includes helpful introductions to chapters, complete references, plus insights into future challenges. More than any other resource, "Proteomics Today" explains how mass spectrometry andits associated tools can turn today's proteomic research challenges into tomorrow's biomedical opportunities. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Nº de ref. del artículo: 9780471648178

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