Protein-Nucleic Acid Interactions

Idioma: inglés

Editorial: Royal Society of Chemistry, GB, 2008

0854042725 / 9780854042722

Librería: Rarewaves USA United, HEBRON, KY, Estados Unidos de AmericaRarewaves USA United

Vendedor de 5 estrellas

Vendedor de IberLibro desde 20 de junio de 2025

Tapa dura

Condición: Nuevo

EUR 193,10

Envío por EUR 44,63 
Se envía dentro de Estados Unidos de America

Cantidad disponible: Más de 20 disponibles

Añadir al carrito
Devoluciones gratuitas de 30 días

Descripción del artículo del vendedor

The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy. High-resolution structures of protein-DNA complexes have been studied since the mid 1980s and a vast array of such structures has now been determined, but surprising and novel structures still appear quite frequently. High-resolution structures of protein-RNA complexes were relatively rare until the last decade. Propelled by advances in technology as well as the realization of RNA's importance to biology, the number of example structures has ballooned in recent years. New insights are now being gained from comparative studies only recently made possible due to the size of the database, as well as from careful biochemical and biophysical studies. As a result of the explosion of research in this area, it is no longer possible to write a comprehensive review. Instead, current review articles tend to focus on particular subtopics of interest. This makes it difficult for newcomers to the field to attain a solid understanding of the basics. One goal of this book is therefore to provide in-depth discussions of the fundamental principles of protein-nucleic acid interactions as well as to illustrate those fundamentals with up-to-date and fascinating examples for those who already possess some familiarity with the field. The book also aims to bridge the gap between the DNA- and the RNA- views of nucleic acid - protein recognition, which are often treated as separate fields. However, this is a false dichotomy because protein - DNA and protein - RNA interactions share many general principles. This book therefore includes relevant examples from both sides, and frames discussions of the fundamentals in terms that are relevant to both. The monograph approaches the study of protein-nucleic acid interactions in two distinctive ways. First, DNA-protein and RNA-protein interactions are presented together. Second, the first half of the book develops the principles of protein-nucleic acid recognition, whereas the second half applies these to more specialized topics. Both halves are illustrated with important real life examples. The first half of the book develops fundamental principles necessary to understand function. An introductory chapter by the editors reviews the basics of nucleic acid structure. Jen-Jacobsen and Jacobsen discuss how solvent interactions play an important role in recognition, illustrated with extensive thermodynamic data on restriction enzymes. Marmorstein and Hong introduce the zoology of the DNA binding domains found in transcription factors, and describe the combinational recognition strategies used by many multiprotein eukaryotic complexes. Two chapters discuss indirect readout of DNA sequence in detail: Berman and Lawson explain the basic principles and illustrate them with in-depth studies of CAP, while in their chapter on DNA bending and compaction Johnson, Stella and Heiss highlight the intrinsic connections between D.…

N° de ref. del artículo LU-9780854042722

Título
Protein-Nucleic Acid Interactions
Autor
Carl C Correll
Editorial
Royal Society of Chemistry, GB
Año de publicación
2008
Estado
New
Encuadernación
Hardback
Idioma
inglés
ISBN 10
0854042725
ISBN 13
9780854042722
Peso del artículo
790 gramos

Rarewaves USA United

HEBRON, KY, Estados Unidos de America

Vendedor de 5 estrellas

Vendedor de IberLibro desde 20 de junio de 2025

Tarifas de envío en Estados Unidos de America

ArtículoDe 30 a 30 días hábilesDe 14 a 14 días hábiles
Primer artículoEUR 44,63EUR 59,81
Los plazos de entrega los establecen los vendedores y varían según el transportista y la ubicación. Los pedidos que pasan por la aduana pueden sufrir retrasos y los compradores son responsables de los aranceles o tarifas asociadas. Los vendedores pueden ponerse en contacto con usted en relación con cargos adicionales para cubrir cualquier aumento en los costes de envío de los artículos.

Métodos de pago

  • Visa
  • Mastercard
  • American Express
  • Carte Bleue
  • Apple Pay
  • Google Pay

Información empresarial del vendedor

Rarewaves USA

10100 West Sample Road, Ste 101
Coral Springs, FL Estados Unidos de America 33065