Proteases: Structure and Function

Idioma: inglés

Editorial: Springer Vienna Feb 2014, 2014

3709108845 / 9783709108840

Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

Vendedor de 5 estrellas

Vendedor de IberLibro desde 11 de enero de 2012

Tapa dura

Condición: Nuevo

EUR 213,99

Envío por EUR 23,00 
Se envía de Alemania a Estados Unidos de America

Cantidad disponible: 2 disponibles

Añadir al carrito
Devoluciones gratuitas de 30 días

Descripción del artículo del vendedor

This item is printed on demand - it takes 3-4 days longer - Neuware -Proteolysis is an irreversible posttranslational modification affecting each and every protein from its biosynthesis to its degradation. Limited proteolysis regulates targeting and activity throughout the lifetime of proteins. Balancing proteolysis is therefore crucial for physiological homeostasis. Control mechanisms include proteolytic maturation of zymogens resulting in active proteases and the shut down of proteolysis by counteracting endogenous protease inhibitors. Beyond the protein level, proteolytic enzymes are involved in key decisions during development that determine life and death from single cells to adult individuals. In particular, we are becoming aware of the subtle role that proteases play in signaling events within proteolysis networks, in which the enzymes act synergistically and form alliances in a web-like fashion. Proteases come in different flavors. At least five families of mechanistically distinct enzymes and even more inhibitor families are known to date, many family members are still to be studied in detail. We have learned a lot about the diversity of the about 600 proteases in the human genome and begin to understand their physiological roles in the degradome. However, there are still many open questions regarding their actions in pathophysiology. It is in this area where the development of small molecule inhibitors as therapeutic agents is extremely promising. Approaching proteolysis as the most important, irreversible post-translational protein modification essentially requires an integrated effort of complementary research disciplines. In fact, proteolytic enzymes seem as diverse as the scientists working with these intriguing proteins. This book reflects the efforts of many in this exciting field of research where team and network formations are essential to move ahead. 576 pp. Englisch.…

N° de ref. del artículo 9783709108840

Título
Proteases: Structure and Function
Autor
Walter Stöcker
Editorial
Springer Vienna Feb 2014
Año de publicación
2014
Estado
Neu
Encuadernación
Buch
Idioma
inglés
ISBN 10
3709108845
ISBN 13
9783709108840
Peso del artículo
1021 gramos
Dimensiones
241x160x37 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Alemania

Vendedor de 5 estrellas

Vendedor de IberLibro desde 11 de enero de 2012

Tarifas de envío de Alemania a Estados Unidos de America

ArtículoDe 5 a 15 días hábilesDe 5 a 15 días hábiles
Primer artículoEUR 23,00EUR 23,00
Los plazos de entrega los establecen los vendedores y varían según el transportista y la ubicación. Los pedidos que pasan por la aduana pueden sufrir retrasos y los compradores son responsables de los aranceles o tarifas asociadas. Los vendedores pueden ponerse en contacto con usted en relación con cargos adicionales para cubrir cualquier aumento en los costes de envío de los artículos.

Métodos de pago

  • Visa
  • Mastercard
  • American Express
  • Carte Bleue
  • Apple Pay
  • Google Pay
  • Cheque
  • Giro bancario
  • PayPal

Información empresarial del vendedor

BuchWeltWeit Ludwig Meier e.K.

Alemania