Pathogenesis and Treatment of Solar Radiation Induced Skin Cancer

This book presents a detailed exploration of the genetic, molecular, and environmental variables in the progression of solar radiation induced skin cancer, or photocarcinoma. The pathogenesis of various types of photocarcinoma, such as melanoma, basal cell carcinoma, actinic keratosis, squamous cell carcinoma, etc. have been addressed.

The book begins with a discussion on the biological mechanisms of UV-induced DNA damage and disruption of DNA repair for comprehensive understanding of the recurrence of photocarcinoma. Numerous biomarkers have been discussed to ascertain how they contribute to the development of photocarcinoma. Following this, the latest advances in the treatment and diagnosis of photocarcinoma have been discussed in detail. The book also explores pharmaceutical development, ethical considerations, surgical and non-surgical approaches, and the role of immunotherapy and targeted therapies in advanced cases. In addition to the clinical and therapeutic perspectives, the book emphasizes patient education, aiming to bridge the gap between clinical practice and public awareness.

Thus this book addresses interdisciplinary subjects within dermatology, photobiology, oncology, pharmaceutical sciences, and life sciences. This book serves as a comprehensive resource on the molecular biology, diagnosis and management of photocarcinoma and is primarily targeted at healthcare professionals, researchers, and pharmaceutical scientists.

Prof. Swarnlata Saraf graduated from the Indian Institute of Technology, BHU, Varanasi, and received her Ph.D. from Dr. H. S. Gour University Sagar, India. She guided 40 Master’s Degrees and 19 Ph.D. students. She wrote 6 books & numerous chapters in edited books, filed patents, and contributed over 200 scientific publications. She served as an editorial board member and reviewer of research journals & books. She served as an expert on national and international research projects & screening committees. According to Google Scholar, she has 12030 citations, an H-index of 51, and an i-10 index of 137, and has received national awards from various professional bodies. She handled research projects funded by national public agencies (India). As per a recently released database by Stanford University, she is among the top 2% of World Scientists. Her area of interest is pharmaceutics, nanotechnology, herbal drug delivery, and cosmetic technology. She has widely travelled abroad, the USA, UK, CONFIDENTIAL MATERIAL Springer India Pvt Ltd Switzerland, Singapore, UAE, and many more for official, professional, and academic activities.

Dr. Ram Kumar Sahu is Associate Professor at the Department of Pharmaceutical Sciences, Hemvati Nandan Bahuguna Garhwal University (A Central University), Chauras Campus, Tehri Garhwal, Uttarakhand. He had more than 19 years of teaching and research experience. He delivered guest lectures at various Universities in Malaysia, Thailand, Philippines, and Indonesia. Dr. Sahu's research highlights the Isolation and characterization of active constituents, novel drug delivery systems, formulation and standardization of herbal drugs, screening and evaluation of various Pharmacological activities of samples. He has received different awards from international and national organizations. Under his supervision & Cosupervision twenty-six PG scholars and three PhD scholars were awarded. He is the author of over 100 scientific publications in Pharmaceutical Science, and contributed 10 books and 08 chapters for Pharmacy books. He has been granted four patents. He received six International and five National awards.