Parallel Single Cell Electrophoresis in a Microchip Platform

Descripción:

Parallel Single Cell Electrophoresis in a Microchip Platform | Nigel Munce (u. a.) | Taschenbuch | 140 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838304489 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. N° de ref. del artículo 101501885

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Sinopsis:

Reseña del editor: Single cell analysis has typically been difficult and challenging to perform in such a way that meaningful statistical information can be extracted. This thesis documents the development of a microchip or lab-on-a-chip platform to perform single cell electrophoresis in parallel separation channels. It describes the use of optical tweezers to select a cell and transport it to a desired separation channel. It also describes the use of electromechanical shearing to lyse a cell. These two techniques are combined with laser-micromachined separation channels to perform simple electrohoresis on the fluorescently labeled cellular contents.