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Chronic Heart Failure: Pathophysiology, Risk Factors, and Mechanisms aims to provide an inclusive overview on Chronic Heart Failure (CHF). This book is focused on the epidemiology, classification, molecular mechanisms, pathophysiology, causes, identification and interactions of heart failure. It will explain the uncertainties and issues in Heart Failure by helping readers understand the physiopathology of CHF in the light of behavioural risk factors. 2D and 3D speckle tracking echocardiography have been used to quantify regional alterations of longitudinal strain and area strain, through their polar projection, which allows a further evaluation of both the site and extent of myocardial damage. The analysis of strain can identify subclinical cardiac failure (myocyte remodelling) which is a major issue in CHF. Myocardial Strain, measure by speckle tracking echocardiography, is frequently attenuated in these conditions and can be utilized for the evaluation of disease progression and the effect of therapeutic interventions as well as prevention because it could be a manifestation of behavioural risk factors. This title will function as an essential reference to both researchers and practicing clinicians, proposing novel methods of research by using behavioural and environmental risk factors as intervention agents, as well as discussing deficiency in the present approaches in management of HF and proposing new methods of early diagnosis and therapies for the clinical management of CHF.

Dr. Ram B Singh is president of the Tsim Tsoum Insitutute in Krakow, Poland. He's an honorary fellow of the Halberg Chronobiology Centre, a member of the Russian Academy of Medical Sciences, a fellow of the International Academy of Cardiovascular Sciences, and former president and founder of the Indian Society of Hypertension, International College of Cardiology, and International College of Nutrition. He is the editor of the World Heart Journal and former professor of medicine at Subharti Medical College. He has contributed over 500 research papers to peer reviewed journals and has edited seven books.

Jan Fedacko, MD, PhD, FICC, FICN is Assistant Professor at Department of Medicine and Centre of Excellency for Atherosclerosis Research at Louis Pasteur University Hospital and Pavol Jozef Safarik University in Kosice, Slovak Republic. After obtaining a diploma in General Medicine of Pavol Jozef Safarik University in Kosice, Slovak Republic (2005) the Ph.D. study (negative pleiotropic effect of the statins and possibilities of its treatment) was completed in year 2010. He is member of executive board of International College of Cardiology, member of International College of Clinical Nutrition, Slovak Association of Cardiology, Slovak Association of Atherosclerosis and member of Editorial Advisory Board of several journals. In the clinical and research area he is focused on preventive cardiology, prevention and treatment of the atherosclerosis deseases, as well as in cardiac imagineg techniques. He has published several papers in domestic and international journals, including several international lectures.

Assoc. Prof. Dr. Krasimira Hristova is specialist cardiologist, expert of echocardiography at University National Heart Hospital, Sofia, Bulgaria and consulting cardiologist at Nadezhda Women’s Hospital , Sofia, Bulgaria . She earned a PhD in applying the newest echocardiographic methods for evaluating the myocardial deformation in patients, following acute myocardial infarction. Assoc. Prof. Hristova specialized in top-ranked universities in Austria and Belgium. She has earned a master’s degree in Advance Medical Imaging in cardiology at Catholic University Leuven, Belgium in 2009. She took part in the development and clinical implementation of the first software for 3D myocardial deformation, working in an international team with colleagues from Belgium and Norway. Authored many scientific papers, holder of the Young Researcher award of the International Society of Hypertension in 2006, she has received honors from multiple national and international organizations.

Dr. Galal Eldin Nagib Elkilany received his BSc and MSc degrees from Tanta University, Egypt and his PhD & MD from the Post-Graduate Institute of Cardiology Department, Tanta University School of Medicine, Egypt. He was a Research Fellow in Thorax Center, Rotterdam, Holland, Erasmus University in Stress Echocardiography Department on 2000/2001. He is a Cardiology Specialist and Faculty in Tanta University Hospital from 1991 until 1998. He also worked as Consultant Cardiologist -degree of Professor of Cardiology 1998-2015, Cairo, Egypt- law No. 115. He is a Clinical Fellow in Milano-Majore Policlinico, Milan, Italy 2007 in cardiac cath. He is a Lab and Partner clinical Fellowship and visitor physician at University of Alabama, Birmingham, USA in 2011. He received a price of Young Investigator Award from Egyptian Society of Cardiology on 1999 & 2001. He has many famous international publications to his credit.