Multifunctional Nanoparticles for Cancer Therapeutic Applications: Design and Challenges describes the use of multifunctional nanoparticles for cancer treatment, highlighting their toxicological evaluation and opportunities for prospective clinical therapeutic development. Besides significant research and clinical success, cancer nanomedicines currently face challenges towards clinical translation and this book aims to shed a light on complex issues. Sections discuss synthetic strategies and functionalization of nanoparticles, routes of administration, biological barriers and how to overcome them, nanoparticles for cancer treatment available in the market, active targeting approach, non-viral gene-based therapy with multifunctional nanoparticles, and the use of nanoparticles in immunotherapy. In addition, the book covers image guided cancer therapy, stem cell targeted therapy, and toxicity. This is a valuable resource for cancer researchers, oncologists, clinicians, and members of the biomedical field who need to understand the potential of multifunctional nanoparticles in cancer drug delivery, diagnosis, and treatment.
Professor Oluwafemi is a fully-fledged academic that is involved in Teaching & Learning, Research, Community Engagement, staff and student mentorship among many other activities. His research interest is in the synthesis of binary, ternary and quaternary semiconductor nanomaterial and nanostructures such as quantum dots, metal nanomaterials, core-shells, doped nanostructures and polymer nanocomposites for different applications which includes biological, (basically for cancer treatment ie imaging, labelling, drug delivery photodynamic therapy and photothermal therapy), optical (development of optical devices), environmental (sensing and determination of environmental pollutants), nanotoxicology and water treatment. He is also involved in the indigenous knowledge system (IKS) for value added chain using different South African medicinal plants. This involves isolation, extraction, biological activity testing, and synthesis of nanomaterial using the plant extract and packaging for pharmaceutical purposes.
Jose Varghese R is a PhD researcher in Department of Chemical Science, University of Johannesburg, South Africa. He has received an integrated master’s degree in Nanoscience and Nanotechnology from Karunya University, Tamil Nadu, India. He has attended various internships and training including from Denmark Technical University. He is currently pursuing his research on designing of multifunctional nanoparticles for cancer imaging and drug delivery. He has published in international journals regarding drug delivery and imaging using nanoparticles and mesoporous silica with book chapter relating to the same.
Prof. Sabu Thomas is a Professor of Polymer Science and Engineering and the Director of the School of Energy Materials at Mahatma Gandhi University, India. Additionally, he is the Chairman of the Trivandrum Engineering Science & Technology Research Park (TrEST Research Park) in Thiruvananthapuram, India. He is the founder director of the International and Inter-university Centre for Nanoscience and Nanotechnology at Mahatma Gandhi University and the former Vice-Chancellor of the same institution.
Prof. Thomas is internationally recognized for his contributions to polymer science and engineering, with his research interests encompassing polymer nanocomposites, elastomers, polymer blends, interpenetrating polymer networks, polymer membranes, green composites, nanocomposites, nanomedicine, and green nanotechnology. His groundbreaking inventions in polymer nanocomposites, polymer blends, green bionanotechnology, and nano-biomedical sciences have significantly advanced the development of new materials for the automotive, space, housing, and biomedical fields. Dr. Thomas has been conferred with Honoris Causa (DSc) by the University of South Brittany, France.
