Molecular Aspects of Innate and Adaptive Immunity

Idioma: inglés

Editorial: Royal Society of Chemistry, GB, 2008

0854046984 / 9780854046980

Librería: Rarewaves USA United, HEBRON, KY, Estados Unidos de AmericaRarewaves USA United

Vendedor de 5 estrellas

Vendedor de AbeBooks desde 20 de junio de 2025

Ver los artículos de este vendedor
Tapa dura

Condición: Nuevo

EUR 157,71

Envío por EUR 43,34 
Se envía dentro de Estados Unidos de America

Cantidad disponible: Más de 20 disponibles

Añadir al carrito
Devoluciones gratuitas de 30 días

Descripción del artículo del vendedor

The understanding, at the molecular level, of the interactions between innate and adaptive arms of the immune system is currently a hot topic, particularly to those interested in immunology - especially susceptibility to infectious diseases. This book provides a survey of topics, in the area of innate and adaptive immunity, which have been researched within the MRC Immunochemistry Unit, at Oxford University, over a period of forty years. The topics include: "antibody structure - for which the first Director of the Immunochemistry Unit, Professor RR Porter, was awarded a Nobel prize in 1972 "the characterization of membrane proteins on lymphoid cells - leading to the concept of these molecules belonging to an immunoglobulin super family "the proteins of the human serum complement system - one of the body's major defences against microbial infection "the human cell -surface integrins and the hyaluronan- binding proteins, which are involved in regulation of inflammation at cell surfaces and within the extracellular matrix "the family of collectin molecules - containing distinct globular carbohydrate -binding domains linked to collagen-like regions - which play important roles in innate immunity in the lungs and bloodstream by immediate recognition and clearance of microbial pathogens Each chapter in the book gives a brief historical background to a topic and then provides a survey of recent advances in the field and are written by internationally recognised renowned experts. The theme running through the chapters is that of protein structure-function relationships - including, amongst others, descriptions of quaternary structures of large oligomeric proteins, of Factor H and C1q binding to specific ligands, and of the chemistry of the mechanism of catalysis of covalent binding of activated C3 and C4 proteins to nucleophilic groups on microbial surfaces. In several chapters excellent descriptions are given with respect to how the immune system can be recruited to combat microbial infection - via proteins of both the innate and adaptive immune systems. The book also includes notable chapters which are excellent examples of the importance of how the isolation, characterisation, protein engineering and crystallisation has resulted in a full understanding of complex protein-protein interactions involved in the recognition and triggering events of important sections of the immune system: -Structure and Function of the C1 Complex - GÚrard J. Arlaud -Chemical Engineering of Therapeutic Antibodies - George T Stevenson -Leukocyte surface proteins - purification and characterisation - A. Neil Barclay -Cell Surface Integrins - Suet-Mien Tan and S.K. Alex Law This book is aimed primarily at established senior research scientists, postdoctoral research scientists and PhD students who have an interest in proteins of the immune system. However, the wide range of immunity system topics, while staying broadly within innate/adaptive immunity will also appeal to a wide.

N° de ref. del artículo LU-9780854046980

Título
Molecular Aspects of Innate and Adaptive Immunity
Autor
Kenneth B M Reid
Editorial
Royal Society of Chemistry, GB
Año de publicación
2008
Estado
New
Encuadernación
Hardback
Idioma
inglés
ISBN 10
0854046984
ISBN 13
9780854046980
Peso del artículo
631 gramos

Rarewaves USA United

HEBRON, KY, Estados Unidos de America

Vendedor de 5 estrellas

Vendedor de AbeBooks desde 20 de junio de 2025

Tarifas de envío en Estados Unidos de America

ArtículoDe 30 a 30 días hábilesDe 14 a 14 días hábiles
Primer artículoEUR 43,34EUR 58,08
Los plazos de entrega los establecen los vendedores y varían según el transportista y la ubicación. Los pedidos que pasan por la aduana pueden sufrir retrasos y los compradores son responsables de los aranceles o tarifas asociadas. Los vendedores pueden ponerse en contacto con usted en relación con cargos adicionales para cubrir cualquier aumento en los costes de envío de los artículos.

Métodos de pago

  • Visa
  • Mastercard
  • American Express
  • Carte Bleue
  • Apple Pay
  • Google Pay

Información empresarial del vendedor

Rarewaves USA

10100 West Sample Road, Ste 101
Coral Springs, FL Estados Unidos de America 33065