Mitochondrial Dysfunction in Neurodegenerative Disorders (eng)
Idioma: inglés
Editorial: Springer, 2018
- Tapa blanda
- Nuevo

Librería: Brook Bookstore On Demand, Napoli, NA, ItaliaBrook Bookstore On Demand
Vendedor de IberLibro desde 11 de octubre de 2022
Condición: Nuevo
EUR 114,26
Cantidad disponible: Más de 20 disponibles
Añadir al carritoDescripción del artículo del vendedor
Questo è un articolo print on demand.
N° de ref. del artículo ed6a51182cd2ea41974258bc2e8190a7
- Título
- Mitochondrial Dysfunction in Neurodegenerative Disorders (eng)
- Autor
- Reeve, Amy K.
- Editorial
- Springer
- Año de publicación
- 2018
- Estado
- new
- Encuadernación
- Encuadernación de tapa blanda
- Idioma
- inglés
- ISBN 10
- 3319803948
- ISBN 13
- 9783319803944
- Edición
- 2ª Edición
- Peso del artículo
- 6,63 kilogramos
This second edition brings together up-to-date contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease and multiple sclerosis. The reader is guided through the basic functions of mitochondria and the mechanisms that lead to their dysfunction, and on to the consequences of this dysfunction for neuronal function before finishing with the modelling of these disorders and discussion of new potential therapeutic targets.
Additional chapters have been added to the book to reflect advances in the field and there are many new contributors and topics, including how mitochondria are degraded and the interaction of the mitochondria with pathologically relevant proteins.
Mitochondrial Dysfunction in Neurodegenerative Disorders provides an accessible, authoritative guide to this important area for neurologists; research and clinical neuroscientists; neuropathologists; and residents with an interest in clinical research.
“Sinopsis” puede pertenecer a otra edición de este título.
Acerca del autor
Amy K. Reeve
Amy did her undergraduate degree in Neuroscience at Edinburgh University before moving to the Mitochondrial Research Group at Newcastle University for her PhD studies. She completed her PhD in the study of the molecular mechanisms of neurodegenerative disease in 2007 and now has her own research group within the Wellcome Trust Centre for Mitochondrial Research. Her current research interests centre around understanding the mechanisms behind the neurodegeneration seen in Parkinson’s disease, and the contribution of mitochondrial dysfunction to these changes. Funded by Parkinson’s UK as a research fellow Amy’s interests lie in understanding how changes within mitochondria, mitochondrial transport and the interaction of mitochondrial with alpha-synuclein contributes to the development of Parkinson’s disease.
Eve M. Simcox
Eve did her undergraduate degree in Biomedical Science at Newcastle University and continued her studies within the Mitochondrial Research Group for her PhD. She completed her PhD in the study of the turnover and dynamics of mitochondria in neurodegenerative disease in 2014 and now works as the impact officer for the faculty of Science, Agriculture and Engineering.
Michael R. Duchen
Michael obtained his Bachelor of Medicine degree from Oxford and London Universities, and moved to UCL for his PhD studies. He has remained at UCL since, where he is now a Professor of Physiology. Michael founded and leads the UCL consortium for Mitochondrial Research and leads a successful research group. Michael's interests lie primarily in understanding the relationships between mitochondrial biology and cell signalling. His research group's main interest lies in understanding the inter-relationship between calcium signalling, mitochondria and free radical biology in cell physiology and pathophysiology. Particular contributions have been made into understanding the contribution of mitochondrial dysfunction to cell injury and death.Doug M. Turnbull
Professor Turnbull is a clinical academic who leads a basic science research programme in conjunction with developing clinical services. He has three main roles.
Director of the Wellcome Trust Centre for Mitochondrial Research. The Wellcome Trust Centre is focused on research to improve the lives of patients with mitochondrial disease. This includes research to identify the genetic defect in patients with mitochondrial disease and his work also focuses understanding the molecular mechanisms underlying the neurological features in patients. With colleagues he is searching for new therapies for patients and actively involved in clinical studies evaluating potential therapies. He has been actively involved in work to prevent the transmission of mitochondrial DNA disease using an IVF technique called mitochondrial donation.Lead for the NHS Highly Specialised Services for Rare Mitochondrial Services for Adults and Children. Professor Turnbull developed this service provides optimum care for patients with mitochondrial disease throughout the UK with Centres in Newcastle, London and Oxford. This service was built on the back of clinical and basic research and the service reviews in excess of 800 patients per year. The service has developed care pathways and patient guidance that are used worldwide of the benefit of patients.
Director MRC/BBSRC Centre for Ageing and Vitality. Professor Turnbull has a major interest in understanding the basic mechanisms involved in human ageing with particular emphasis on the role of mitochondria. The MRC Centre is focused on understanding how these mechanisms are influenced by lifestyle interventions and studies aimed at promoting healthy ageing.“Acerca de” puede pertenecer a otra edición de este título.
Brook Bookstore On Demand
Napoli, NA, Italia
Vendedor de IberLibro desde 11 de octubre de 2022
Tarifas de envío de Italia a Estados Unidos de America
| Artículo | De 25 a 40 días hábiles | De 60 a 60 días hábiles |
|---|---|---|
| Primer artículo | EUR 42,00 | EUR 511,00 |
Métodos de pago
Descripción de la tienda
Account dedicated to Print on Demand titles. Brook Bookstore offers a wide selection of books with a continuously updated catalog and fast shipments all over the world. We hold distribution rights with all of the publishers we promote and are in continuous search of new interesting titles to propose to our customers. We are part of Brandon Group SRL (an Italian company) and all of the orders are shipped from Europe. Depending on availability orders will be picked from our different warehouses. CONTACT US If you have any questions please do not hesitate to contact us sending a message to our store. We have a well prepared customer service team who will be happy to assist you. Our working hours are from Monday to Friday from 9:30 to 18:30 (CET, UTC +1) so messages received during the weekends might be responded with a slight delay but we guarantee you will get back to you as soon as possible. RETURNS If you want to return your order, please submit your request through Abebooks platform. Returns requests are managed case by case by our team and always in line with Abebooks policies: AbeBooks’ Return Policy guarantees that you can return any book for a refund within 30 days, when the return is due to an error on the bookseller’s part. When the motive of the return is not due to an error of the seller it is up to Brook Bookstore to accept the return or else after studying the case. CANCELLATION You can send a cancellation request to our customer service team while the package has not yet been shipped. After that we cannot ensure we can retrieve the parcel but we suggest you to get in touch with us in order to verify the case. INVOICE You can request the invoice to be issued together with the shipment of the order or, at the latest, in the same month of the shipment. …
Especialidad
Print on DemandInformación empresarial del vendedor
Brandon Group S.R.L.
Via Vannella Gaetani 27, Brandon Group
Napoli, NA Italia 80121
Condiciones de venta
Brook Bookstore On Demand ofrece una amplia selección de libros con un catálogo continuamente actualizado y envíos rápidos a todo el mundo. Tenemos los derechos de distribución con todas las editoriales que promocionamos y estamos en continua búsqueda de nuevos títulos interesantes para proponer a nuestros clientes. Somos parte de Brandon Group SRL (una compañía italiana) y todos los pedidos se envían desde Europa. Dependiendo de la disponibilidad los pedidos se recogerán de nuestros diferentes centros de distribución.
Derecho al desistimiento
Si es un consumidor, puede rescindir el contrato de acuerdo con lo siguiente. Por consumidor se entiende cualquier persona física que actúe con fines ajenos a su actividad comercial, empresarial, oficio o profesión.
Información sobre el derecho de desistimiento
Derecho legal de desistimiento
Tiene derecho a rescindir este contrato en un plazo de 14 días sin dar ningún motivo.
El periodo de desistimiento vencerá a los 14 días desde que usted, o un tercero que no sea el transportista e indicado por usted, adquiera la posesión física del último bien o del último lote o pieza.
Para ejercer el derecho de desistimiento, complete de forma electrónica y envíe una declaración clara en nuestro sitio web, desde "Mis compras" en "Mi cuenta". Le enviaremos sin demora un acuse de recibo de dicho desistimiento a través de un soporte duradero (por ejemplo, por correo electrónico).
Para cumplir con el plazo de desistimiento, basta con que envíe su comunicación relativa al ejercicio del derecho de desistimiento antes de que venza el periodo de desistimiento.
Efectos del desistimiento
Si rescinde este contrato, le reembolsaremos todos los pagos que hayamos recibido de usted, incluidos los gastos de envío (excepto los gastos adicionales que surjan si elige un tipo de envío que no sea el tipo de envío estándar más económico que ofrecemos).
Podemos hacer una deducción del reembolso por la pérdida de valor de cualquier bien suministrado, si la pérdida es el resultado de una manipulación innecesaria por su parte.
Efectuaremos el reembolso sin demoras indebidas y, a más tardar, 14 días después de que se nos informe de su decisión de rescindir este contrato.
Efectuaremos el reembolso utilizando el mismo medio de pago que utilizó para la transacción inicial, a menos que haya acordado expresamente lo contrario; en cualquier caso, no incurrirá en ningún cargo como resultado de dicho reembolso.
Podremos retener el reembolso hasta que hayamos recibido los bienes o hasta que nos haya presentado una prueba de que los ha devuelto, lo que ocurra primero.
Deberá devolver los bienes o entregarlos a Brook Bookstore On Demand, Bristol, United Kingdom, +39 3485885209, sin demoras indebidas y, en cualquier caso, en un plazo máximo de 14 días a partir del día en que nos comunique su desistimiento del presente contrato. El plazo se cumple si devuelve la mercancía antes de que venza el periodo de 14 días. Tendrá que asumir los gastos directos de devolución de los bienes. Usted solo es responsable de la disminución del valor de los bienes como resultado de una manipulación distinta a la necesaria para establecer la naturaleza, las características y el funcionamiento de los bienes.
Excepciones al derecho de desistimiento
El derecho de desistimiento no se aplica a lo siguiente:
- La entrega de periódicos, diarios o revistas, con la excepción de los contratos de suscripción; y
- El suministro de contenido digital que no se proporcione en un soporte tangible (por ejemplo, en un CD o DVD) si, al hacer el pedido, aceptó que podíamos empezar a entregarlo y que no podría desistir una vez iniciada la entrega.