Microfluidics and Multi Organs on Chip

P. V. Mohanan

ISBN 10: 9811913811 ISBN 13: 9789811913815

Editorial: Springer Singapore, 2023

Idioma: Ingl�s

Condici�n: Nuevo Encuadernaci�n de tapa blanda

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Detalles bibliogr�ficos

T�tulo

Microfluidics and Multi Organs on Chip

Editor

Springer Singapore

Fecha de publicaci�n

2023

Idioma

Ingl�s

ISBN 10

9811913811

ISBN 13

9789811913815

Encuadernaci�n

Taschenbuch

Estado

Neu

Dimensiones

Peso

1216 gramos

Cat�logos de vendedores

B�cher

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Sinopsis

This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation,ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.

Acerca del autor

Dr. PV. Mohanan is a Fellow of the National Academy of Science and Royal Society of Biologists, UK. He was a JSPS Post-Doctoral Fellow at the University of Tsukuba, Japan, in the field of Neurotoxicity. He joined Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Govt. of India, in 1989. As a toxicologist, he has been intimately associated with all the medical devices/technologies developed at SCTIMST. Currently, he heads the Division of Toxicology and a visiting professor and visiting researcher at Toyo University, Japan, and a Certified Biological Safety Specialist. He received a lifetime achievement award from the Society of Toxicology India for the outstanding contribution to toxicology research. Dr. Mohanan made significant contributions to the development of medical device regulations in India. He received a certificate of appreciation from the Hon. Minister of Science and Technology, Govt. of India, contributed to getting full adherent status on GLP from the OECD. He has authored more than 250 publications and edited 4 books. Presently, he is the Secretary-General of Society of Toxicology, India, and General Secretary of Indian JSPS Alumni Association.

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