Neuware -Protein pharmaceuticals form a fast-growing category in the arsenal of drugs. In the coming years, the patents on a number of the first-generation protein pharmaceuticals will expire, opening the door for the development of biogenerics into the market. However, it is very difficult to characterize these compounds so that the results can be replicated in a generic form. This volume details the nature of the different analytical techniques and how they are relevant for characterizing pharmaceutical proteins. In addition to serving the analytical chemist, this book is needed by the formulation scientist who is responsible for design and formulation of a pharmaceutical protein that can be monitored during production and over time. It also will be useful for students, fellows, and research scientists who are working in the academic world and in the pharmaceutical/biotechnology industry on basic aspects of proteins.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 692 pp. Englisch.

N� de ref. del art�culo 9780971176720

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Detalles bibliogr�ficos

T�tulo

Methods for Structural Analysis of Protein Pharmaceuticals

Editor

American Assoc. Of Pharm. Scientists Dez 2005

Fecha de publicaci�n

2005

Idioma

Ingl�s

ISBN 10

0971176728

ISBN 13

9780971176720

Encuadernaci�n

Buch

Estado

Neu

Cat�logos de vendedores

Acerca de

Sinopsis

Ultraviolet Absorption Spectroscopy.- Pluorescence Spectroscopy.- Circular Dichroism Spectroscopy.- Fourier Transform Infrared Spectroscopy.- Raman Spectroscopy.- Nuclear Magnetic Resonance Spectroscopy.- Light Scattering.- Liquid Chromatography.- Capillary Electrophoresis.- Analytical Ultracentrifugation.- Field-Flow Fractionation.- Mass Spectrometery: Protein Conformational Analysus and Molecular Recognition.- Mass Spectrometry: Proteomics.- Immunoassays.- Surface Plasmon Resonance.- Microarray-Based Methods.- Calorimetry.- Atomic Force Microscopy.- Molecular Modeling.- Concluding Remarks: Analytical Methods of Protein Formulations.

Rese�a del editor

Protein pharmaceuticals form a fast-growing category in the arsenal of drugs. This book explores the nature of different analytical techniques and the way in which they are related to pharmaceutical proteins. In addition to serving the analytical chemist, this book is needed by the formulation scientist who is responsible for design and formulation of a pharmaceutical protein that can be monitored during production and over time.

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Descripci�n de la librer�a

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