Membrane Traffic in Protozoa, Part A

Idioma: inglés

Editorial: Elsevier Science and Technology, GB, 1994

1559386282 / 9781559386289

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Membranes are highly dynamic and operate not only as inert boundaries, but the packages they carry around in a cell are well addressed fro appropriate delivery. This holds for a variety of endomembrane systems engaged in exo- and endocytosis, for organelles along the biosynthetic pathway, phagosomes, and lysosomes. It also holds for the establishment of functional surface properties. Cell pairing (conjugation) phenomena are a good model for the problem of how a cell can discriminate between "self" and "non-self". On the other hand parasitic sporozoa developed to experts in masking their molecular sur-"face"by frequent shedding of their variant antigens. The discovery of their glycosyl-phosphatidylinositol (GPI) anchor has led to the discovery, in polar epithelial cells, of a specific targeting mechanism for GPI-anchored surface glycoproteins. Over one hundred such proteins have been detected in metazoans since then.Many of these basic aspects are dealt with in this book using quite different methodical approaches. Of course, there are many more aspects previously known from metazoan systems and such aspects then had to be verified also for Protozoa systems and such aspects then had to be verified also for protozoa. In this context, it is fascinating to see how basic cellular functions are maintained - with variations of the basic theme - throughout evolution.However, sometimes cell biologists dedicated to work with protozoa have to live with a regrettable phenomenon. Colleagues working with "higher" eukaryotic cells are frequently unaware of the fact that the primary input may have come from work with protozoa. Some phenomena may even be rediscovered inadvertently. In this sense, this book should address not only colleagues working with protozoa but also many of our fellow cell biologists working with metazoan cells.…

N° de ref. del artículo LU-9781559386289

Título
Membrane Traffic in Protozoa, Part A
Autor
H. Plattner
Editorial
Elsevier Science and Technology, GB
Año de publicación
1994
Estado
New
Encuadernación
Hardback
Idioma
inglés
ISBN 10
1559386282
ISBN 13
9781559386289
Peso del artículo
720 gramos

Rarewaves.com USA

London, London, Reino Unido

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