Volume 25, entitled Modern Avenues in Metal-Nucleic Acid Chemistry, of the series Metal Ions in Life Sciences (MILS), provides a timely overview of selected relevant developments in a field which previously had a pronounced focus on fundamental chemistry aspects such as coordination principles, structural chemistry, and consequences for biological processes and disease-related medicinal issues. More recently, also as a consequence of the advent of supramolecular chemistry, advancements in nanochemistry, and new bio-analytical methods, novel aspects of this field have emerged. MILS-25 gives a state-of-the-art account on the present state of research in this field, addressing, among others, porous materials, non-covalent interactions, stimuli-responsive bioconjugates, DNA-templated metal arrays and nanoclusters, genotyping, guanine quadruplexes, and riboswitches. It consists of 15 comprehensive chapters with over 1600 citations, 160 figures (90 of them in color), with key contributions from 40 international experts from Europe, Asia, and America. It is an essential resource for scientists from numerous disciplines, ranging from materials science to biochemistry, by way of classical chemistry and physics.

It offers an update on nucleic acid – metal complex bioconjugates and their applications
It provides an insight into coordination polymers involving nucleic acid components
It covers a wide range of nucleic acids, from DNA duplexes, triplexes and quadruplexes to RNA

Acerca del autor

Jens M�ller holds a Chair of Inorganic Chemistry (2018) at the Department of Chemistry and Pharmacy, Westf�lische Wilhelms-Universit�t M�nster, Germany. He obtained his doctoral degree (1999, summa cum laude) from the Technische Universit�t Dortmund, working with Bernhard Lippert. After a postdoctoral stay in the groups of Stephen J. Lippard (MIT) and Gerhard Wagner (Harvard Medical School), he started his independent career at the Technische Universit�t Dortmund in 2002, funded by the prestigious Emmy Noether Programme. After having received his Habilitation in 2008, he became Professor of Inorganic Chemistry at the Westf�lische Wilhelms-Universit�t M�nster. His research focuses on the bioinorganic chemistry of nucleic acids, with a particular interest in metal-mediated base pairing. He was Dean of Student Affairs from 2011–2014, Chair of the European research initiative COST Action CM1105 ("Functional metal complexes that bind to biomolecules"), and guest Editor of several themed issues of chemistry journals. Since 2018, he has served as the Editor of Inorganica Chimica Acta. He is the Chair of EuroBIC-17 (2024 in M�nster, Germany).

Bernhard Lippert retired in 2011 from Chair of Bioinorganic Chemistry at the Technische Universit�t Dortmund, Germany. He received his Ph.D. degree from Technische Universit�t M�nchen (TUM), Germany, in 1974. Following a postdoctoral stay with Barnett Rosenberg at the Biophysics Department of Michigan State University, USA, he started his independent research at TUM, which was focused on fundamental aspects of interactions of metal species, notably of Pt, with nucleobases, as well as supramolecular constructs derived from these components. During his career at TUM, the University of Freiburg, Germany, and TU Dortmund, he has trained 70 PhD students and in addition numerous Bachelor and Master students as well as postdoctoral fellows, a fair number of whom eventually earned academic positions. Results of his group’s work are documented in over 400 refereed scientific articles and have been communicated at many international conferences and lectureships. He served the community as Editorial Board member of several journals (Inorg. Chem., Dalton Trans., Inorg. Chim. Acta, J. Biol. Inorg. Chem., Biometals), and was the Editor of Inorg. Chim. Acta from 2008 to 2019. He was (Co)-Editor of a number of themed issues in chemistry journals, and Editor of the book Cisplatin: Chemistry and Biochemistry of a Leading Anticancer Drug, which reviewed the knowledge on Pt antitumor complexes at the turn of the century. He has been involved in the management of European research activities in the COST frame, has been the Secretary of EuroBIC conferences for 11 years and has organized numerous scientific meetings such as the "EURESCO Research conference on the Inorganic Side of Molecular Architecture" (2002), EuroBIC-7 (2004), and "4th EuCheMS Conference on Nitrogen Ligands" (2008), among others. Since 2014 he has been an Honorary Member of the Society of Biological Inorganic Chemistry (SBIC).

"Sobre este t�tulo" puede pertenecer a otra edici�n de este libro.

Descripci�n de la librer�a

Ver la p�gina web de la librer�a

Informaci�n empresarial del vendedor

Speedy Hen
Unit 1 Falcon Park, Neasden Lane, London, NW10 1RZ, United Kingdom

Condiciones de venta y env�o

Condiciones de venta

Orders usually ship within 2 business days. Shipping costs are based on books weighing 2.2 LB, or 1 KG. If your book order is heavy or oversized, we may contact you to let you know extra shipping is required.

Derecho a cancelaci�n

Si eres un consumidor puedes cancelar el presente contrato de acuerdo con lo indicado a continuaci�n. Son consumidores las personas f�sicas que act�en con un prop�sito ajeno a su actividad comercial, empresarial, oficio o profesi�n.

Documento de informaci�n al consumidor y usuario sobre el desistimiento

Derecho de desistimiento:

Tienes derecho a desistir del presente contrato en un plazo de 14 d�as naturales sin necesidad de justificaci�n.

El plazo de desistimiento expirar� a los 14 d�as naturales del d�a en que t� o un tercero que hayas indicado, distinto del transportista, adquiera la posesi�n material del �ltimo bien, componente o pieza.

Para ejercer el derecho de desistimiento, deber�s notificarnos a Speedy Hen, 100 Chiltern Court, 188 Baker Street, NW1 5SX, London, United Kingdom, 44 08452419973, de tu decisi�n de desistir del contrato a trav�s de una declaraci�n inequ�voca (por ejemplo, una carta enviada por correo postal, fax o correo electr�nico). Podr�s utilizar el modelo de formulario de desistimiento que figura a continuaci�n, aunque su uso no es obligatorio. Tienes asimismo la opci�n de cumplimentar y enviar electr�nicamente el modelo de formulario de desistimiento o cualquier otra declaraci�n inequ�voca a trav�s de nuestro sitio web a "Mis pedidos" en "Mi cuenta". Si recurres a esta opci�n, te comunicaremos sin demora en un soporte duradero (por ejemplo, por correo electr�nico) la recepci�n de dicho desistimiento.

Para cumplir el plazo de desistimiento, basta con que la comunicaci�n relativa al ejercicio por tu parte de este derecho sea enviada antes de que venza el plazo correspondiente.

Consecuencias del desistimiento:

En caso de desistimiento por tu parte, te devolveremos todos los pagos recibidos de ti, incluidos los gastos de entrega (con la excepci�n de los gastos adicionales resultantes de la elecci�n por tu parte de una modalidad de entrega diferente a la modalidad menos costosa de entrega ordinaria que ofrezcamos) sin ninguna demora indebida y, en todo caso, a m�s tardar 14 d�as naturales a partir de la fecha en la que se nos informes de tu decisi�n de desistir del presente contrato. Procederemos a efectuar dicho reembolso utilizando el mismo medio de pago empleado por ti para la transacci�n inicial, a no ser que hayas dispuesto expresamente lo contrario; en todo caso, no incurrir�s en ning�n gasto como consecuencia del reembolso.

Podremos retenerte el reembolso hasta haber recibido los bienes, o hasta que hayas presentado una prueba de la devoluci�n de los mismos, seg�n qu� condici�n se cumpla primero. Deber�s devolvernos o entregarnos directamente los bienes a Speedy Hen, SpeedyHen Returns, Po Box 48, BN23 6WB, Westham, United Kingdom, 44 08452419973, sin ninguna demora indebida y, en cualquier caso, a m�s tardar en el plazo de 14 d�as naturales a partir de la fecha en que nos comuniques tu decisi�n de desistimiento del contrato. Se considerar� cumplido el plazo si efect�as la devoluci�n de los bienes antes de que haya concluido dicho plazo. Deber�s asumir el coste directo de devoluci�n de los bienes. Solo ser�s responsable de la disminuci�n de valor de los bienes resultante de una manipulaci�n distinta a la necesaria para establecer la naturaleza, las caracter�sticas y el funcionamiento de los bienes.

Excepciones al derecho de desistimiento:

La entrega de peri�dicos, publicaciones especializadas o revistas con la excepci�n de contratos de suscripci�n; y
La entrega de contenido digital (incluyendo apps, software digital e-books, MP3, etc.) que no hubiera sido entregado en un medio tangible (por ejemplo: CD o DVD), si al realizar tu pedido has aceptado que podemos proceder al env�o del producto y que no resulta posible su cancelaci�n una vez comienza la entrega.

Modelo de formulario de desistimiento

(S�lo debe cumplimentar y enviar el presente formulario si desea desistir del contrato)

A la atenci�n de: (Speedy Hen, 100 Chiltern Court, 188 Baker Street, NW1 5SX, London, United Kingdom, 44 08452419973)

Por la presente le comunico/comunicamos* que desisto de mi/desistimos de nuestro* contrato de venta del siguiente bien/prestaci�n del siguiente servicio*

Pedido el/recibido el*:

Nombre del consumidor y usuario o de los consumidores y usuarios:

Domicilio del consumidor y usuario o de los consumidores y usuarios:

Firma del consumidor y usuario o de los consumidores y usuarios (solo si el presente formulario se presenta en papel):

Fecha:

* Eliminar en su caso

Condiciones de env�o

Shipping costs are based on books weighing 2.2 LB, or 1 KG. If your book order is heavy or oversized, we may contact you to let you know extra shipping is required.

Tarifas de env�o de Reino Unido a Estados Unidos de America

Tarifas de env�o de Reino Unido a Estados Unidos de America
Cantidad del pedido	De 60 a 60 d�as h�biles	De 60 a 60 d�as h�biles
Primer art�culo	EUR 47.43	EUR 49.74

Los plazos de entrega los establecen los vendedores y var�an seg�n el transportista y la ubicaci�n. Los pedidos que pasan por la aduana pueden sufrir retrasos y los compradores son responsables de los aranceles o tarifas asociadas. Los vendedores pueden ponerse en contacto con usted en relaci�n con cargos adicionales para cubrir cualquier aumento en los costes de env�o de los art�culos.