High-Throughput Screening Methods in Toxicity Testing

Idioma: inglés

Editorial: John Wiley and Sons Inc, US, 2013

1118065638 / 9781118065631

Librería: Rarewaves.com USA, London, London, Reino UnidoRarewaves.com USA

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Explores the benefits and limitations of the latest high-throughput screening methods With its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity. Moreover, it enables them to comply with the latest standards set forth by the U.S. National Research Council's "Toxicity Testing in the 21st Century: A Vision and Strategy" and the E.U.'s REACH legislation. Readers will discover a variety of state-of-the-science, high-throughput screening methods presented by a group of leading authorities in toxicology and toxicity testing. High-Throughput Screening Methods in Toxicity Testing is divided into five parts: General aspects, including predicting the toxicity potential of chemicals and drugs via high-throughput bioactivity profilingAssessing different cytotoxicity endpointsAssessing DNA damage and carcinogenesisAssessing reproductive toxicity, cardiotoxicity, and haematotoxicityAssessing drug metabolism and receptor-related toxicity Each chapter describes method principles and includes detailed information about data generation, data analysis, and applications in risk assessment. The authors not only enumerate the advantages of each high-throughput method over comparable conventional methods, but also point out the high-throughput method's limitations and potential pitfalls. In addition, the authors describe current research efforts to make high-throughput toxicity screening even more cost effective and streamlined. Throughout the book, readers will find plenty of figures and illustrations to help them understand and perform the latest high-throughput toxicity screening methods. This book is ideal for toxicologists and other researchers who need to implement high-throughput screening methods for toxicity testing in their laboratories as well as for researchers who need to evaluate the data generated by these methods.

N° de ref. del artículo LU-9781118065631

Título
High-Throughput Screening Methods in Toxicity Testing
Autor
Pablo Steinberg
Editorial
John Wiley and Sons Inc, US
Año de publicación
2013
Estado
New
Encuadernación
Hardback
Idioma
inglés
ISBN 10
1118065638
ISBN 13
9781118065631
Peso del artículo
939 gramos

Rarewaves.com USA

London, London, Reino Unido

Vendedor de 5 estrellas

Vendedor de AbeBooks desde 11 de junio de 2025

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