Getting to Good : Research Integrity in the Biomedical Sciences

This book represents the first comprehensive, gold standard reader on research integrity in the biomedical sciences. Now more than ever, the responsible conduct of research (RCR) has become critically important as new technologies affect research practices in both positive and negative ways. Since learning to do science and practicing it brings researchers into contact with a vast array of ethical issues, it is critical to know the standards and how they are evolving. Indeed, research integrity requires scientists at all levels to operate ethically in a system that supports ethical practice.   This unique, foundational text covers all the relevant areas -- subject protection, research misconduct and conflict of interest as well as newly quantified concerns about research bias and non-reproducibility, as well as other unique issues. Developed by renowned experts, this compelling title discusses the full range of practices and policies that should support research that is honestly produced and disseminated. It also specifically incorporates topics noted by the National Institutes of Health as essential and required for training in RCR. Getting to Good – Research Integrity in the Biomedical Sciences is a major contribution to the literature on bioethics and will serve as an invaluable resource for all researchers, students, administrators and professionals interested in research ethics and integrity.

Arthur L Caplan, PhD

 Currently the Drs. William F and Virginia Connolly Mitty Professor and founding head of the Division of Bioethics at New York University Langone Medical Center in New York City.  He is the head of the ethics program in the Global Institute for Public Health at NYU.

 Prior to coming to NYU he was the Sidney D. Caplan Professor of Bioethics at the University of Pennsylvania Perelman School of Medicine in Philadelphia where he created the Center for Bioethics and the Department of Medical Ethics.  Caplan has also taught at the University of Minnesota, where he founded the Center for Biomedical Ethics, the University of Pittsburgh, and Columbia University.  He received his PhD from Columbia University. Caplan is the author or editor of thirty-two books and over 600 papers in peer reviewed journals.  His most recent book is Replacement Parts: The Ethics of Procuring and Replacing Organs in Humans (GeorgetownUniversity Press, 2015).He has served on a number of national and international committees including as the Chair, National Cancer Institute Biobanking Ethics Working Group; the Chair of the Advisory Committee to the United Nations on Human Cloning; the Chair of the Advisory Committee to the Department of Health and Human Services on Blood Safety and Availability; a member of the Presidential Advisory Committee on Gulf War Illnesses; the special advisory panel to the National Institutes of Mental Health on human experimentation on vulnerable subjects, the Wellcome Trust advisory panel on research in humanitarian crises, and the Co-Director of the Joint Council of Europe/United Nations Study on Trafficking in Organs and Body Parts. 

He is currently the ethics advisor to DOD/DARPA on synthetic biology, a member of the University of Pennsylvania’s External Advisory Committee for its Orphan Disease Center and a member of the Ethics and Ebola Working Group of the World Health Organization. Dr. Caplan also serves as the Chairperson of the Compassionate Use Advisory Committee (CompAC), an independent group of internationally recognized medical experts, bioethicists and patient representatives which advises Janssen/J&J about requests for compassionate use of some of its investigational medicines.

Caplan is the recipient of many awards and honors including the McGovern Medal of the American Medical Writers Association and the Franklin Award from the City of Philadelphia.  He received the Patricia Price Browne Prize in Biomedical Ethics for 2011.  He was a person of the Year-2001 from USA Today.  He was described as one of the ten most influential people in science by Discover magazine in 2008.  He has also been honored as one of the fifty most influential people in American health care by Modern Health Care magazine, one of the ten most influential people in America in biotechnology by the National Journal, one of the ten most influential people in the ethics of biotechnology by the editors of Nature Biotechnology and one of the 100 most influential people in biotechnology by Scientific American magazine.  In 2014 he was selected to receive the Public Service Award from the National Science Foundation/National Science Board which honors individuals and groups that have made substantial contributions to increasing public understanding of science and engineering in the United States.

He holds seven honorary degrees from colleges and medical schools.  He is a fellow of the Hastings Center, the NY Academy of Medicine, the College of Physicians of Philadelphia, the American College of Legal Medicine and the American Association for the Advancement of Science.

Barbara K. Redman, PhD, MBE is Associate, Division of Medical Ethics, New York Langone Medical Center.  She is former Dean of the Wayne State University School of Nursing andover the past decade has produced an impressive record of scholarship in research misconduct/research integrity including a contracted study for the US Office of Research Integrity.  In 2014-15 she served as an Edmond J Safra Center for Ethics Network Fellow at Harvard University, studying whistleblowing in cases of research misconduct.  This book proposal reflects Dr. Redman’s experience in teaching research integrity to graduate students, faculty and international trainees.  She has expertise in philosophical foundations of bioethics, social science empirical methods, health policy and the ethics of health care.  She is the sole author of two recent books in bioethics/research ethics:  The Ethics of Patient Self-Management of Chronic Disease, Springer, 2012, and Research Misconduct Policy in Biomedicine:  Beyond the “Bad Apple”, MIT Press, 2013.

 

Dr. Redman holds a PhD from the University of Minnesota, a masters in bioethics from the University of Pennsylvania and honorary doctorates from Georgetown University and the University of Colorado.  She has held fellowships at The Johns Hopkins University School of Public Health, Georgetown University Kennedy Institute of Ethics, and Harvard Medical School Division of Medical Ethics.  Dr. Redman is a fellow of the American Academy of Nursing and a recipient of the University of Minnesota Regents Award.