Genomics in the Cloud : Using Docker, GATK, and WDL in Terra

Dr. Geraldine A. Van der Auwera is the Director of Outreach and Communication for the Data Sciences Platform (DSP) at the Broad Institute of MIT and Harvard. As part of her outreach role, she serves as an educator and advocate for researchers who use DSP software and services including GATK, the Broad's industry-leading toolkit for variant discovery analysis; the Cromwell/WDL workflow management system; and Terra.bio, a cloud-based analysis platform that integrates computational resources, methods repository and data management in a user-friendly environment. Van der Auwera was originally trained as a microbiologist, earning her Ph.D. in Biological Engineering from the Universite catholique de Louvain (UCL) in Belgium in 2007, then surviving a 4-year postdoctoral stint at Harvard Medical School. She joined the Broad Institute in 2012 to become Benevolent Dictator For Life of the GATK user community, leaving behind the bench and pipette work forever. Dr. Brian O'Connor is the Director of the Computational Genomics Platform at the University of California Santa Cruz (UCSC) Genomics Institute. There, he focuses on the development and deployment of large-scale, cloud-based systems for analyzing genomic data. These include the NHGRI AnVIL and NHLBI Bio Data Catalyst platforms as well as the Dockstore site for workflow and tool sharing. Brian is active in standards efforts and is the cochair of the Global Alliance for Genomics and Health Cloud Work Stream where he works on API standards for cloud interoperability. Brian joined UCSC from the Ontario Institute for Cancer Research where his previous projects included leading the technical implementation of worldwide, cloud-based analysis systems for the PanCancer Analysis of Whole Genomes project, creating the Dockstore, and managing a successful rebuild of the International Cancer Genome Consortium's Data Portal.