Frontiers in Combating Antibacterial Resistance: Current Perspectives and Future Horizons

The rise of modern antimicrobial drug resistance has evolved into a pressing global health crisis, challenging the very foundation of our ability to combat infectious diseases. The overuse and accessibility of antibiotics, particularly in emerging nations, have given rise to resilient "superbugs," rendering common medications ineffective. This escalating challenge poses a significant threat to public health and leads to heightened healthcare costs, prolonged patient stays, and increased mortality rates. As communities grapple with the urgent need for a coordinated response, a comprehensive understanding of antimicrobial drug resistance and innovative strategies becomes paramount. Frontiers in Combating Antibacterial Resistance: Current Perspectives and Future Horizons is meticulously crafted for academic scholars, researchers, and healthcare professionals. It addresses this critical issue head-on and serves as a beacon of knowledge and a solution-oriented guide. With a focus on elucidating the mechanisms behind antimicrobial drug resistance and exploring emerging therapeutic targets, the book presents an in-depth analysis of the problem. It spans environmental, genetic, and climatic factors influencing resistance, delving into cutting-edge technologies and sustainable strategies for prevention. By offering a holistic view of the issue and proposing evidence-based solutions, the book is an indispensable resource for those seeking to navigate the complex landscape of antimicrobial drug resistance.

Ajmer Singh Grewal , Professor (Pharmaceutical Chemistry), Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana (India), is having academic and research experience of 13+ years in medicinal chemistry. He had completed PhD in Pharmaceutical Sciences in the subject area of Computational and Medicinal Chemistry from I.K. Gujral Punjab Technical University, Jalandhar, Punjab (India) in 2020. His present areas of research include structure-based drug design and medicinal chemistry of MMP2 and MMP9 inhibitors as anticancer agents, antibacterial drug resistance (NDM-1), GK activators as anti-diabetic agents, AR inhibitors for diabetic complications, PPAR agonists for metabolic syndrome, multi-potent anti-Alzheimer’s agents, selective PDE4 & 7 inhibitors as anti-inflammatory agents and environmental chemistry. He owns to his credit a total of more than 100 publications in national and international journals of repute, 20 book chapters, 15 books (10 edited), and 6 patents. He serves as a reviewer for reputed international journals published by Elsevier, Springer, Wiley, SAGE, and Frontiers. He is a life member of the Indian Society for Technical Education (ISTE). He had worked on various sophisticated analytical instruments including UV-Vis and FTIR spectrophotometer, Flash chromatography, and HPLC; and also, on various molecular modelling softwares including ChemSketch, ChemDraw and Marvin Sketch; Open Babel and Frog2 for structure optimization; PyMOL for molecular graphics, Glide (Schrodinger), AutoDock, AutoDock Vina, Discovery Studio (Dassault Systemes BIOVIA), Omega and Open Eye for in silico molecular docking studies.

Ashwani Kumar is presently working as Principal, Global Research Institute of Pharmacy, Yamuna Nagar. Professionally, he is a Medicinal Chemist with expertise in the design and development of synthetic methodologies dealing with various organic transformations, multistep synthesis of medicinally active heterocyclics along with bioactive natural product analogs. He has done PhD in Pharmaceutical Sciences from IKGPTU University, Jalandhar and M. Pharm in Pharmaceutical Chemistry from ISF College of Pharmacy affiliated to PTU, Jalandhar. He is an alumnus of GGSCOP, Yamuna Nagar at graduate level. He has 15+ years of teaching experience. His expertise in the Computer Aided Drug Design, Analytical Method Development and Validation; Natural Product Chemistry, Formulation Development using NDDS field enabled him to conduct research in areas of diverse nature. His research areas include like molecular docking, pharmacophore modelling, virtual screening, pharmaceutical quality control, pharmaceutical technology and synthesis of medicinally active compounds. His expertise is simply recognized by the fact that he is acting as referee for review of manuscripts for large number of international journals of repute. He has more than 90 research/review publications - most of them in international journals of repute to his credit in addition to 06 books with international Publishers, 08 patent (Design), 05 patents (Formulation) and 11 copyrights. He is a recipient of project grant (Rs. 7,00,000/-) under MSME Innovative Scheme (Incubation, Design & IPR) in 2022; Training grant (Rs. 50,000/-) from Pharmacy Council of India, New Delhi under PCI CBIT Scheme in 2021 and Conference grant (Rs. 20,000/-) from Patent Felicitation Centre, HSCST, DST, Govt. of Haryana for conducting one day national workshop on Patents filing procedure for students and small-scale industries in 2019.He is honored asLate Prof. (Dr.) M. L. Shroff “Pharma Recognition Award” by PharmaLok (NGO), New Delhi in 2022; Innovational Ambassador (Design Thinking & Innovation) by MHRD Innovational Cell, AICTE, New Delhi in 2021; Bentham Ambassador (2022-23, 2020-2021, 2019-20) by Bentham Science Publishers; e-certificate for Highly Cited Research in Fitoterapia by Elsevier in 2016.He is Life Member of the Indian Society for Technical Education (LM - 136464); Association of Pharmaceutical Teachers in India (HA/LM-153); Education Research and Development Association (ERDA/INDLM/792/1223) and Society for Research Development in Health Sciences (SRDHS/11).He has delivered more than 20 guest talks on various topics of healthcare domain in collaboration with different Government and Non-government organizations.

Kunal Nepali is an Associate Professor in the School of Pharmacy, Taipei Medical University, Taiwan. Dr. Kunal joined the School of Pharmacy, Taipei Medical University as an Assistant Professor on 17.01.2019 and is currently handling independent research projects funded by the Ministry of Science and Technology (MOST) as well as Taipei Medical University. He has expertise spanning medicinal chemistry and organic synthesis with ten years of experience in a broad range of drug development projects. He obtained his PhD degree in Pharmaceutical Chemistry in the year 2012 from ISF College of Pharmacy, Moga, Punjab. During his doctoral studies, he worked under the supervision of Dr. K.L Dhar, a pioneer organic and medicinal chemist of India and systematically explored various areas of rational drug design and natural product chemistry. Along with the teaching assignments, he was actively involved in research projects and explored various areas of Catalytic Chemistry and Medicinal Chemistry. With an overwhelming stint as a teacher and a researcher, he was determined to expand the horizon of his expertise by gaining international exposure. To accomplish this, he moved to Taipei Medical University, Taiwan in October 2014 as a post-doctoral fellow in the laboratories of Professor Jing Ping Liou. His research work at the post-doctoral level involved the design of new chemical entities with desired biological activities and the development/optimization of synthetic procedures for the preparation of compounds along with structure-activity relationship studies. It was his exemplary research work at the post-doctoral level that earned him a highly competitive faculty position at the School of Pharmacy, Taipei Medical University. He made a significant contribution to the field of Medicinal Chemistry throughout his post-doctoral tenure and earned the outstanding Post-Doctoral Researcher award, Taipei Medical University for five consecutive times from 2014 to 2018. He is the author of a good number of research/review articles and is an ad-hoc reviewer of various reputed journals in the field of biomedical sciences. He has also received various recognitions as a reviewer for Medicinal Research Reviews, European Journal of Medicinal Chemistry, Bioorganic Chemistry, Bioorganic and Medicinal Chemistry Letter, and others.

Geeta Deswal is presently working as Professor (Pharmacognosy) at Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana (India). She has obtained PhD from M.M. Deemed to be University, Mullana, Haryana (India) in Quality Audit of Herbal Formulations in 2017. She is an expert in bioactivity-guided extraction and isolation of phytoconstituents, standardization of drugs and herbal formulations, and phytochemical screening of medicinal plants and plant tissue culture. She is also working on the formulation and evaluation of herbal products as antimicrobial agents. She has worked on UV-Visible spectrophotometer, HPLC, Soxhlet Apparatus, Clevenger Apparatus, Sonicator, Rota evaporator, and Thin Layer Chromatography and Column Chromatography. She owns to her credit 40 publications in national and international journals of repute, 12 book chapters and 10 books. She is also a Life member of the Association of Pharmaceutical Teachers of India (APTI), the Indian Society for Technical Education (ISTE) the Indian Pharmacy Graduates Association (IPGA). She received the “Young Achiever Award” by Shree Balaji Books and Innovational Ambassador by the Innovational Cell, MHRD, AICTE, New Delhi.

Arun Lal Srivastav works as an Associate Professor at Chitkara University, Himachal Pradesh, India. He obtained Ph.D. degree from the Indian Institute of Technology (BHU), Varanasi, India. He has done post-doctoral research at National Chung Hsing University, Taiwan. He is currently involved in teaching Environmental Science, Environmental Engineering, Disaster Management, and Design Thinking to undergraduate engineering students. His research interests include Water Quality Surveillance, Climate Change, Water Treatment, River Ecosystems, Soil Health, Phytoremediation and Waste Management. He has published over 80 research papers in various prestigious journals (Elsevier, Springer Nature, IWA, Wiley, etc.), including book chapters and conference papers. He is the editor of 17 books with Elsevier, Nova, Springer, IGI Global, and Wiley.