From Enzyme Models to Model Enzymes

Idioma: inglés

Editorial: Royal Society of Chemistry, GB, 2009

0854041753 / 9780854041756

Librería: Rarewaves.com USA, London, London, Reino UnidoRarewaves.com USA

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Descripción del artículo del vendedor

Designing artificial systems with catalytic efficiencies to rival those of natural enzymes is one of the great challenges facing science today. Our current level of understanding fails the basic, practical test - designing and making artificial systems with catalytic efficiencies to rival those of natural enzymes. Chemists and bio-scientists are well aware of this problem, and "artificial enzymes" have been a "hot topic" for many years. However, until now, there has been no book devoted specifically to this subject. This is the first book to provide a critical introduction to, and overview of, this exciting area. It is aimed at students and more senior researchers with specialist or general interests in the field. The book starts with a systematic overview of the most important properties of natural enzymes, with special emphasis on mechanisms and efficiency of catalysis. This is followed by a summary of the mechanisms involved in the major classes of reaction they catalyze, and spells out the logical progression from simple mechanistic models for particular reactions to the first, rudimentary artificial enzymes catalyzing them. Catalytic efficiency is the key criterion for inclusion. An analysis of the strengths and limitations of the classical design-based approach to catalysis by enzyme mimics leads on to a discussion of recent advances which use selection methods coupled with iterative techniques for creating and improving catalysts by natural methods. The comparison of natural and artificial catalysts requires a quantitative understanding based on the interpretation of kinetic measurements. Key skills in data interpretation are introduced in a guided approach that connects the formal treatment of kinetic measurements with their chemical and biological interpretation.…

N° de ref. del artículo LU-9780854041756

Título
From Enzyme Models to Model Enzymes
Autor
Anthony J Kirby, Florian Hollfelder
Editorial
Royal Society of Chemistry, GB
Año de publicación
2009
Estado
New
Encuadernación
Hardback
Idioma
inglés
ISBN 10
0854041753
ISBN 13
9780854041756
Peso del artículo
571 gramos
Dimensiones
15.6 x 1.98 x 23.4 cm

Rarewaves.com USA

London, London, Reino Unido

Vendedor de 5 estrellas

Vendedor de IberLibro desde 11 de junio de 2025

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