Digital Information Methods of Polarization, Mueller-Matrix and Fluorescent Microscopy (eng)

This book highlights the effectiveness of differential diagnosis in the degree of severity of joint pathology from a clinical, biophysical, and informational point of view. It includes the following information blocks:

• Two-dimensional digital polarization microscopy of polycrystalline films of synovial fluid and determination of the coordinate distributions of the orientation and phase parameters of the microscopic image from a set of parameters of the Stokes vector.

• Mueller-matrix mapping of polycrystalline films of synovial fluid and determination of a set of coordinate distributions (Mueller-matrix images (MMI)) of azimuthal-invariant elements that characterize manifestations of optical activity and linear birefringence.

• Development of algorithms for polarization reproduction of distributions of linear and circular birefringence of polycrystalline films of synovial fluid.

• Identification of digital statistical, correlation and wavelet criteria of polarization and Mueller-matrix differential diagnosis of the degree of severity of joint pathology.

• Determination of maps of laser-induced fluorescence of synovial fluid polycrystalline films.

• Identification of statistical and correlational criteria for fluorescent differential diagnosis of the degree of severity of joint pathology.

• Operational characteristics of the power of the methods of azimuth-invariant polarization, Mueller-matrix and laser autofluorescence microscopy of polycrystalline films of synovial fluid.

Dr. Vasyuk V.L.- Orthopedic surgeon of the highest category, Ph. D., Doctor of medicine, professor, Head of the Department of Traumatology and Orthopedics at Bukovinian State Medical University, Supervisor at Regional center "Traumatology, endoprosthetics, joint and spine pathology". Author of 372 publications, 6 monographs, 220 articles, 25 Patents of USSR, 8 Patents of Ukraine.

Dr. Kalashnikov A.V. – MD, professor, head of the department of Trauma Injuries to Locomotion System and Problems of Osteosynthesis at the SI “The Institute of Traumatology and Orthopedics, NAMS of Ukraine”, 

Dr. Protsyuk Victor V.- Orthopedic surgeon of the highest category, Ph. D., Supervisor at Regional center "Traumatology, endoprosthetics, joint and spine pathology".

Dr. Yuriy A. Ushenko obtained his Ph.D. in optics and laser physics in 2006, and D.Sc. in optics and laser physics from the Taras Shevchenko National University of Kyiv in 2015. He is currently Professor and Head of the Computer Science Department at Chernivtsi National University, Ukraine. His current research interests include laser polarimetry, holography, and application of AI in life sciences.

Dr. Alexander Dubolazov is an Associate Professor at the Chernivtsi National University. He received his BS and MS degrees in optics from the Chernivtsi National University in 2006 and 2007, respectively, and his PhD degree in optics, laser physics from the Chernivtsi National University in 2010.  He is the author of more than 100 journal papers and has written five book chapters. His current research interests include laser polarimetry, holography etc.

Dr. Alexander G. Ushenko  is Head of Optics and Publishing Department at the Chernivtsi National University, Ukraine. He received his BS and MS degrees in optics from the Chernivtsi State University in 1975 and 1977, respectively, and his Ph.D. degree inoptics and laser physics from the Chernivtsi State University in 1983.  In 2000, he obtained D.Sc. in optics and laser physics. His current research interests include laser polarimetry, polarization interferometry, and digital holography.

Dr. Zheng Jun is an associate research fellow in Research Institute of Zhejiang University-Taizhou. He obtained the Ph.D. degree in Control Theory and Control Engineering from Zhejiang University, China in 2005. He has been engaged in the application research of industrial automation system and its advanced control, photoelectric detection and intelligent perception for a long time. In recent years, Zheng Jun has presided over two major cooperation research projects with China Railway Construction Electrification Bureau Group and participated in two national key research and development projects.